ID Q5YXU0_NOCFA Unreviewed; 681 AA.
AC Q5YXU0;
DT 23-NOV-2004, integrated into UniProtKB/TrEMBL.
DT 23-NOV-2004, sequence version 1.
DT 27-MAR-2024, entry version 104.
DE SubName: Full=Putative dehydrogenase {ECO:0000313|EMBL:BAD57001.1};
GN OrderedLocusNames=NFA_21550 {ECO:0000313|EMBL:BAD57001.1};
OS Nocardia farcinica (strain IFM 10152).
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Nocardiaceae;
OC Nocardia.
OX NCBI_TaxID=247156 {ECO:0000313|EMBL:BAD57001.1, ECO:0000313|Proteomes:UP000006820};
RN [1] {ECO:0000313|EMBL:BAD57001.1, ECO:0000313|Proteomes:UP000006820}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=IFM 10152 {ECO:0000313|EMBL:BAD57001.1,
RC ECO:0000313|Proteomes:UP000006820};
RX PubMed=15466710; DOI=10.1073/pnas.0406410101;
RA Ishikawa J., Yamashita A., Mikami Y., Hoshino Y., Kurita H., Hotta K.,
RA Shiba T., Hattori M.;
RT "The complete genomic sequence of Nocardia farcinica IFM 10152.";
RL Proc. Natl. Acad. Sci. U.S.A. 101:14925-14930(2004).
CC -!- SIMILARITY: Belongs to the enoyl-CoA hydratase/isomerase family.
CC {ECO:0000256|ARBA:ARBA00005254}.
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DR EMBL; AP006618; BAD57001.1; -; Genomic_DNA.
DR RefSeq; WP_011208686.1; NC_006361.1.
DR AlphaFoldDB; Q5YXU0; -.
DR STRING; 247156.NFA_21550; -.
DR GeneID; 61132916; -.
DR KEGG; nfa:NFA_21550; -.
DR eggNOG; COG1012; Bacteria.
DR eggNOG; COG2030; Bacteria.
DR HOGENOM; CLU_025047_0_0_11; -.
DR OrthoDB; 9759612at2; -.
DR Proteomes; UP000006820; Chromosome.
DR GO; GO:0016620; F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor; IEA:InterPro.
DR CDD; cd07128; ALDH_MaoC-N; 1.
DR Gene3D; 3.10.129.10; Hotdog Thioesterase; 1.
DR InterPro; IPR016161; Ald_DH/histidinol_DH.
DR InterPro; IPR016163; Ald_DH_C.
DR InterPro; IPR016162; Ald_DH_N.
DR InterPro; IPR015590; Aldehyde_DH_dom.
DR InterPro; IPR029069; HotDog_dom_sf.
DR InterPro; IPR002539; MaoC-like_dom.
DR InterPro; IPR011966; PaaN-DH.
DR NCBIfam; TIGR02278; PaaN-DH; 1.
DR PANTHER; PTHR43111; ALDEHYDE DEHYDROGENASE B-RELATED; 1.
DR PANTHER; PTHR43111:SF1; ALDEHYDE DEHYDROGENASE B-RELATED; 1.
DR Pfam; PF00171; Aldedh; 1.
DR Pfam; PF01575; MaoC_dehydratas; 1.
DR SUPFAM; SSF53720; ALDH-like; 1.
DR SUPFAM; SSF54637; Thioesterase/thiol ester dehydrase-isomerase; 1.
PE 3: Inferred from homology;
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000006820}.
FT DOMAIN 14..447
FT /note="Aldehyde dehydrogenase"
FT /evidence="ECO:0000259|Pfam:PF00171"
FT DOMAIN 548..653
FT /note="MaoC-like"
FT /evidence="ECO:0000259|Pfam:PF01575"
SQ SEQUENCE 681 AA; 71134 MW; 0C0E3FC37572BFC9 CRC64;
MSELLQSYVG GRWVTPPDEG TPLLSAVDGS VVARLSSTGV DRAHMVDHAR TVGGPALAAL
TFHERAARLK ALGKYLLEHK AELYAISAHT GATERDSAVD IDGGAGTLLS YASKATRELP
NDTVYLDGGV ERLGRKGTFA GQHIYTARRG VAVQINAFNF PVWGFLEKLA PAFIAGVPSL
VKPAGQTAYL TEAAFRLIIE SGLLPEGSVQ LLCGSAGDLL DHLGGQDSVA FTGSAETAAL
LRAHPVVVRE AVRFTAEADS LNASILGADV TPGSPEFELF VGQLVTEMTV KAGQKCTAIR
RALVPEPMVD AVVDAVRERL ARVVVGAPGA DGVTMGALAG IDQREEVRKA VRALTKSAQI
VFGDPESVTV VGADAATGAF LSPILLRCDD REAVEPHEVE AFGPVSTVLG YRDTADAIAL
AARGKGSLVA SVVTGDTAVA REIALGLAPY HGRVLVLDTV DARESTGHGS PLPTLVHGGP
GRAGGGEELG GIRGVLHHMQ RTAVQGSPAV LTAVGRRWVT GADQVRGDVH PFRKDLGQLK
LGDTIVAGPR RVTLDDIGHF AEFTGDTFYA HTDPEAAAAN PLFGGIVAHG YLVVSLAAGL
FVDPAPGPVL ANFGVDNLRF LTPVKAEDEL TVTLTAKQIT PRTSAAYGEV RWDATVTNQN
DEAVATYDVL TLVAKPEGET K
//
