ID   Q5Z170_NOCFA            Unreviewed;      1584 AA.
AC   Q5Z170;
DT   23-NOV-2004, integrated into UniProtKB/TrEMBL.
DT   23-NOV-2004, sequence version 1.
DT   27-MAR-2024, entry version 123.
DE   SubName: Full=Putative ATP-dependent DNA helicase {ECO:0000313|EMBL:BAD55821.1};
GN   OrderedLocusNames=NFA_9760 {ECO:0000313|EMBL:BAD55821.1};
OS   Nocardia farcinica (strain IFM 10152).
OC   Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Nocardiaceae;
OC   Nocardia.
OX   NCBI_TaxID=247156 {ECO:0000313|EMBL:BAD55821.1, ECO:0000313|Proteomes:UP000006820};
RN   [1] {ECO:0000313|EMBL:BAD55821.1, ECO:0000313|Proteomes:UP000006820}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=IFM 10152 {ECO:0000313|EMBL:BAD55821.1,
RC   ECO:0000313|Proteomes:UP000006820};
RX   PubMed=15466710; DOI=10.1073/pnas.0406410101;
RA   Ishikawa J., Yamashita A., Mikami Y., Hoshino Y., Kurita H., Hotta K.,
RA   Shiba T., Hattori M.;
RT   "The complete genomic sequence of Nocardia farcinica IFM 10152.";
RL   Proc. Natl. Acad. Sci. U.S.A. 101:14925-14930(2004).
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DR   EMBL; AP006618; BAD55821.1; -; Genomic_DNA.
DR   RefSeq; WP_011207506.1; NC_006361.1.
DR   STRING; 247156.NFA_9760; -.
DR   GeneID; 61131797; -.
DR   KEGG; nfa:NFA_9760; -.
DR   eggNOG; COG1201; Bacteria.
DR   HOGENOM; CLU_002025_3_1_11; -.
DR   OrthoDB; 9815222at2; -.
DR   Proteomes; UP000006820; Chromosome.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR   GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   CDD; cd17922; DEXHc_LHR-like; 1.
DR   CDD; cd18796; SF2_C_LHR; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR013701; DEAD/DEAH_assoc.
DR   InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR   InterPro; IPR014001; Helicase_ATP-bd.
DR   InterPro; IPR001650; Helicase_C.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   PANTHER; PTHR47962:SF5; ATP-DEPENDENT HELICASE LHR-RELATED; 1.
DR   PANTHER; PTHR47962; ATP-DEPENDENT HELICASE LHR-RELATED-RELATED; 1.
DR   Pfam; PF00270; DEAD; 1.
DR   Pfam; PF08494; DEAD_assoc; 1.
DR   Pfam; PF00271; Helicase_C; 1.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM00487; DEXDc; 1.
DR   SMART; SM00490; HELICc; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR   PROSITE; PS51194; HELICASE_CTER; 1.
PE   4: Predicted;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW   Helicase {ECO:0000313|EMBL:BAD55821.1};
KW   Hydrolase {ECO:0000313|EMBL:BAD55821.1};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW   Reference proteome {ECO:0000313|Proteomes:UP000006820}.
FT   DOMAIN          32..225
FT                   /note="Helicase ATP-binding"
FT                   /evidence="ECO:0000259|PROSITE:PS51192"
FT   DOMAIN          264..446
FT                   /note="Helicase C-terminal"
FT                   /evidence="ECO:0000259|PROSITE:PS51194"
FT   REGION          952..996
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1323..1355
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1584 AA;  169675 MW;  A6BB2D2D0C3E1FBF CRC64;
     MVSFSTAVFS RATQEWFDGA FPAPTSAQLG AWQAIAAGEH TLVVAPTGSG KTLSAFLWAI
     DELAATAPDP DAPRGTTVLY ISPLKALAVD VERNLRAPLV GITQTAKRLG LDPPEITVGV
     RSGDTPAAAR RSMQRTPPDI LITTPESLFL MLTSAARETL RTVRTVIVDE VHAIAGSKRG
     AHLALSLARL DMLTERPVQR IGLSATVRPA EEVGRFLVGA APITIVSPPA PKTFDLTVRV
     PVPDMTEPGE SDQPGSIWPH VDEAIVDLVL AHRSSIVFAN SRRLAERLTA RLNEAYAARV
     GDPVSTSHAP PAQLGPSTEV IHGAEQLLAR AHHGSVSKEQ RALIEDDLKS GRLRCVVATS
     SLELGIDMGA VDLVVQVEAP PSVASGLQRI GRAGHQVGEI SRGVLFPKHR TDVIHCAVAA
     ERMVTGRIEA LRIPAHPLDI LAQQTVAVCA LEPIDVDAWF DAVRATGSFA TLPRSAYESV
     LDLLSGRYPS DEFAELRPRL VWDRDAGTLT GRPGAQRLAV TSGGAIPDRG MFAVYMVGEK
     NTRVGELDEE MVYESRVGDV FALGATSWRI EEITFDRVLV TPAFGQPGRL PFWHGDGLGR
     PAELGAALGE FVRKAAKQTA NRADAAADTD LGGLLAGAGL DANAATNLVA LLDDQRAATG
     QLPTDKTLVV ERFRDELGDW RLVLHSPFGL PVHAPWALAV GARLRERFGV DAAPNASDDG
     IVVRLPDTTD DPPGAELFVF EPDEIDDLVT EQVGGSALFA SRFRECAARA LLLPRRDPGK
     RAPLWQQRQR SAQLLDVARK FPDFPILLET VRECLRDVYD LPALRDLLGR VARRQVRLVE
     VETATPSPFA NALLFDYIGQ FMYEGDSPLA ERRAAALSLD SGLLAELLGR VELRELLDTA
     VLEQTERELQ RLTPERRARD AEGLADLLRL LGPLTPEEAG QRCVRGRADE VADTGLPEAD
     PSVAAAATRS ADGAPDGSMA GAEPEPSEFP ADDGTGPHHR WFAELVAARR ALEVSFAGRT
     WWAAVEDASR LRDALGVPLP IGTPAAFIEP VADPLGDLVG RYARTHAPFG LDAVARRFGI
     GPAVAATALH RLVTEKRVVE GEFTPGASGR EWCDTQVLRR LRRRSLAAAR HEVEPVATAA
     FGRFLPAWQH VGTGELRGVD GVATVVEQLA GVPAPASAWE SLILPARVRD YTPAMLDELT
     ATGEVIWSGH GAITAKDGWI ALHLAEQAPF TLPPPDDIEL SETHLRLLAA LGATPAPRAG
     ADGPVPLPPV LHGGGAYFFR QLSDATGLLD DTAVAAALWE LVWAGLVAGD TFAPVRALLS
     GTARTTTAHR TPRRAPRGRA YLPRPSLPTR TGPPAVAGRW SLLPERVTDN TVRAHATADI
     LLERYGVLTR GSVQNEGVPG GFALMYRVLT EFEDRGRCRR GYFVDSLGGA QFSTTDVVDR
     LRSHDTDRGR PGDRAPAPSG LVLAACDPAN PYGAALPWPK NEGEGGHRPG RKAGALVVLV
     GGELVLYLER GGKTLLTFTT DPTARRAAAT ALAEVVFHGR VDALVIDRID GETVHGNTFA
     AFLTDAGFAD TPRGLRLRST HARR
//