ID   Q5Z200_NOCFA            Unreviewed;       373 AA.
AC   Q5Z200;
DT   23-NOV-2004, integrated into UniProtKB/TrEMBL.
DT   23-NOV-2004, sequence version 1.
DT   27-MAR-2024, entry version 101.
DE   RecName: Full=cutinase {ECO:0000256|ARBA:ARBA00013095};
DE            EC=3.1.1.74 {ECO:0000256|ARBA:ARBA00013095};
GN   OrderedLocusNames=NFA_6960 {ECO:0000313|EMBL:BAD55541.1};
OS   Nocardia farcinica (strain IFM 10152).
OC   Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Nocardiaceae;
OC   Nocardia.
OX   NCBI_TaxID=247156 {ECO:0000313|EMBL:BAD55541.1, ECO:0000313|Proteomes:UP000006820};
RN   [1] {ECO:0000313|EMBL:BAD55541.1, ECO:0000313|Proteomes:UP000006820}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=IFM 10152 {ECO:0000313|EMBL:BAD55541.1,
RC   ECO:0000313|Proteomes:UP000006820};
RX   PubMed=15466710; DOI=10.1073/pnas.0406410101;
RA   Ishikawa J., Yamashita A., Mikami Y., Hoshino Y., Kurita H., Hotta K.,
RA   Shiba T., Hattori M.;
RT   "The complete genomic sequence of Nocardia farcinica IFM 10152.";
RL   Proc. Natl. Acad. Sci. U.S.A. 101:14925-14930(2004).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=cutin + H2O = cutin monomers.; EC=3.1.1.74;
CC         Evidence={ECO:0000256|ARBA:ARBA00034045};
CC   -!- SIMILARITY: Belongs to the AB hydrolase superfamily.
CC       {ECO:0000256|ARBA:ARBA00008645}.
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DR   EMBL; AP006618; BAD55541.1; -; Genomic_DNA.
DR   RefSeq; WP_011207228.1; NC_006361.1.
DR   AlphaFoldDB; Q5Z200; -.
DR   ESTHER; nocfa-q5z200; Xaa-Pro-like_dom.
DR   GeneID; 61131528; -.
DR   KEGG; nfa:NFA_6960; -.
DR   eggNOG; COG1073; Bacteria.
DR   HOGENOM; CLU_048587_1_0_11; -.
DR   OrthoDB; 5902829at2; -.
DR   Proteomes; UP000006820; Chromosome.
DR   GO; GO:0052689; F:carboxylic ester hydrolase activity; IEA:UniProt.
DR   Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR   InterPro; IPR029058; AB_hydrolase.
DR   InterPro; IPR022742; Hydrolase_4.
DR   PANTHER; PTHR22946:SF9; POLYKETIDE TRANSFERASE AF380; 1.
DR   PANTHER; PTHR22946; UNCHARACTERIZED; 1.
DR   Pfam; PF12146; Hydrolase_4; 1.
DR   SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
PE   3: Inferred from homology;
KW   Hydrolase {ECO:0000313|EMBL:BAD55541.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000006820}.
FT   DOMAIN          43..158
FT                   /note="Serine aminopeptidase S33"
FT                   /evidence="ECO:0000259|Pfam:PF12146"
SQ   SEQUENCE   373 AA;  39849 MW;  B88D23D82503371A CRC64;
     MATDESIDRG AATAAVQRRD VEFLSDGVPC AAWLYTTPGA PGPRPIVIMG HGLGAVREMR
     LAAFAERFAA NGWSVLVFDY RHLGASGGRP RQLLDIGRQL ADWRAAVAFA RTLPEVDVDR
     IALWGTSFGG GHVLQVGSGN PQVAAIVAQC PFTDGPASLI SRLRTGPLSA VALMAVGILD
     TARSWLGSKP ILVPMAGTSW MPAFVASPDA IAGASALLPP GTRLSRRSSA LLRRLPSVRA
     RLSENIELTI ADDREPVTKV GRDSIWGVFR GPGNDFDAAN ALAARLVLRL PLYRPGRAMA
     RSGVPTLLCV CDNDAAAPAE TTKRRARGLA HVRVKTYPCD HFDIYLGTYF EDAVRDQIDF
     LAEQFADTVP AAT
//