ID Q5Z361_NOCFA Unreviewed; 438 AA.
AC Q5Z361;
DT 23-NOV-2004, integrated into UniProtKB/TrEMBL.
DT 23-NOV-2004, sequence version 1.
DT 27-MAR-2024, entry version 104.
DE SubName: Full=Putative cyclopropane fatty acid synthase {ECO:0000313|EMBL:BAD55130.1};
GN OrderedLocusNames=NFA_2880 {ECO:0000313|EMBL:BAD55130.1};
OS Nocardia farcinica (strain IFM 10152).
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Nocardiaceae;
OC Nocardia.
OX NCBI_TaxID=247156 {ECO:0000313|EMBL:BAD55130.1, ECO:0000313|Proteomes:UP000006820};
RN [1] {ECO:0000313|EMBL:BAD55130.1, ECO:0000313|Proteomes:UP000006820}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=IFM 10152 {ECO:0000313|EMBL:BAD55130.1,
RC ECO:0000313|Proteomes:UP000006820};
RX PubMed=15466710; DOI=10.1073/pnas.0406410101;
RA Ishikawa J., Yamashita A., Mikami Y., Hoshino Y., Kurita H., Hotta K.,
RA Shiba T., Hattori M.;
RT "The complete genomic sequence of Nocardia farcinica IFM 10152.";
RL Proc. Natl. Acad. Sci. U.S.A. 101:14925-14930(2004).
CC -!- SIMILARITY: Belongs to the CFA/CMAS family.
CC {ECO:0000256|ARBA:ARBA00010815}.
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DR EMBL; AP006618; BAD55130.1; -; Genomic_DNA.
DR RefSeq; WP_011206817.1; NC_006361.1.
DR AlphaFoldDB; Q5Z361; -.
DR STRING; 247156.NFA_2880; -.
DR GeneID; 61131132; -.
DR KEGG; nfa:NFA_2880; -.
DR eggNOG; COG2230; Bacteria.
DR HOGENOM; CLU_026434_6_2_11; -.
DR OrthoDB; 9782855at2; -.
DR Proteomes; UP000006820; Chromosome.
DR GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR GO; GO:0008610; P:lipid biosynthetic process; IEA:InterPro.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR CDD; cd02440; AdoMet_MTases; 1.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR003333; CMAS.
DR InterPro; IPR020803; PKS_MeTfrase.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR PANTHER; PTHR43667; CYCLOPROPANE-FATTY-ACYL-PHOSPHOLIPID SYNTHASE; 1.
DR PANTHER; PTHR43667:SF1; CYCLOPROPANE-FATTY-ACYL-PHOSPHOLIPID SYNTHASE; 1.
DR Pfam; PF02353; CMAS; 1.
DR PIRSF; PIRSF003085; CMAS; 1.
DR SMART; SM00828; PKS_MT; 1.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
PE 3: Inferred from homology;
KW Lipid metabolism {ECO:0000256|ARBA:ARBA00023098};
KW Reference proteome {ECO:0000313|Proteomes:UP000006820};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 167..401
FT /note="Polyketide synthase methyltransferase"
FT /evidence="ECO:0000259|SMART:SM00828"
SQ SEQUENCE 438 AA; 49135 MW; 130F4A096E0A3A82 CRC64;
MTTFKDRSDV FADLGTKLSI AEIFETLIDG EVPIRLTAYD GSSTGPADSR YSLDIRTPRG
INYLATAPGD LGMARAYISG DMTAGGVHPG DPYEALKALQ NMRFRRPSAL ALVTIARSLG
WERLKPVAPP PQETLPRWRR IAFEGLRHTK GRDAEAIHHH YDVSNTFYEY VLGPSMTYTC
AVYGDENWTL EQAQENKYRL IFDKLRLKEG DRLLDIGCGW GGMVRYAARR GVRVIGATLS
AEQADWAQKK IAEEGLGDLA EVRHCDYRDV PETDFDAVSS IGLTEHIGVH NYPFYFGYIK
SKLRDGGLFL NHCITRPDNT RSTKAGDFID RYVFPDGELI GSGRIISDIQ NVGLEVLHEE
NLREHYALTL HEWCKNLVAN WDACVAEVGE GTAKVWGLYM AGSRLGFQRN VVQLHQVLGV
KLPADGDWTV PLRPWWQP
//
