ID Q5ZK54_CHICK Unreviewed; 370 AA.
AC Q5ZK54; F1NAT4;
DT 23-NOV-2004, integrated into UniProtKB/TrEMBL.
DT 23-NOV-2004, sequence version 1.
DT 27-MAR-2024, entry version 98.
DE SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:CAG31889.1};
GN ORFNames=RCJMB04_13c10 {ECO:0000313|EMBL:CAG31889.1};
OS Gallus gallus (Chicken).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae;
OC Phasianinae; Gallus.
OX NCBI_TaxID=9031 {ECO:0000313|EMBL:CAG31889.1};
RN [1] {ECO:0000313|EMBL:CAG31889.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=CB {ECO:0000313|EMBL:CAG31889.1};
RC TISSUE=Bursa {ECO:0000313|EMBL:CAG31889.1};
RX PubMed=15642098; DOI=10.1186/gb-2004-6-1-r6;
RA Caldwell R.B., Kierzek A.M., Arakawa H., Bezzubov Y., Zaim J., Fiedler P.,
RA Kutter S., Blagodatski A., Kostovska D., Koter M., Plachy J., Carninci P.,
RA Hayashizaki Y., Buerstedde J.M.;
RT "Full-length cDNAs from chicken bursal lymphocytes to facilitate gene
RT function analysis.";
RL Genome Biol. 6:R6.1-R6.9(2005).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=GTP + H2O = GDP + H(+) + phosphate; Xref=Rhea:RHEA:19669,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:37565,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:58189;
CC Evidence={ECO:0000256|ARBA:ARBA00001702};
CC PhysiologicalDirection=left-to-right; Xref=Rhea:RHEA:19670;
CC Evidence={ECO:0000256|ARBA:ARBA00001702};
CC -!- SIMILARITY: Belongs to the SIMIBI class G3E GTPase family. ZNG1
CC subfamily. {ECO:0000256|ARBA:ARBA00034320}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AJ720230; CAG31889.1; -; mRNA.
DR RefSeq; NP_001026607.1; NM_001031436.1.
DR AlphaFoldDB; Q5ZK54; -.
DR SMR; Q5ZK54; -.
DR STRING; 9031.ENSGALP00000016477; -.
DR PaxDb; 9031-ENSGALP00000016477; -.
DR GeneID; 427347; -.
DR KEGG; gga:427347; -.
DR CTD; 427347; -.
DR VEuPathDB; HostDB:geneid_427347; -.
DR eggNOG; KOG2743; Eukaryota.
DR InParanoid; Q5ZK54; -.
DR OMA; HSQGFET; -.
DR OrthoDB; 1010489at2759; -.
DR Bgee; ENSGALG00000010147; Expressed in muscle tissue and 13 other cell types or tissues.
DR GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR CDD; cd03112; CobW-like; 1.
DR Gene3D; 3.30.1220.10; CobW-like, C-terminal domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR036627; CobW-likC_sf.
DR InterPro; IPR011629; CobW-like_C.
DR InterPro; IPR003495; CobW/HypB/UreG_dom.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR13748:SF31; COBW DOMAIN-CONTAINING PROTEIN 1-RELATED; 1.
DR PANTHER; PTHR13748; COBW-RELATED; 1.
DR Pfam; PF02492; cobW; 1.
DR Pfam; PF07683; CobW_C; 1.
DR SMART; SM00833; CobW_C; 1.
DR SUPFAM; SSF90002; Hypothetical protein YjiA, C-terminal domain; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 2: Evidence at transcript level;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801}.
SQ SEQUENCE 370 AA; 40992 MW; 7E704E4823C9E168 CRC64;
MEDEDCPDLV PIDVGIVQDS EPGSGRKIPV TIITGYLGAG KTTLLNYILT EQHSKRIAVI
LNEFGEGSAL EKSLAISQGG ELYEEWLELR NGCLCCSVKD NGVKAIENLM QKRGKFDYIL
LETTGLADPG AVASMFWVDS ELGSDIYLDG IVSVVDAKHG LQHLTEEKPE GLVNEAARQV
ALADLIIINK TDLVSGEELN KVRASVRSIN GLVKILETQR SRVDLSNVLD LHAFDSLSGI
SLQKKLENMK TAHAHLDKGI VTVTFEVLGN IKEENLNLFI QNLLWEKNVK DKTGRTMDVI
RLKGLVSIQG KSHQVIVQGV HELYDLEETA VAWKEDEKRT NRLVLIGRNL NKEIIKEVFI
ETVSEKHESS
//
