ID Q5ZRL4_LEGPH Unreviewed; 130 AA.
AC Q5ZRL4;
DT 23-NOV-2004, integrated into UniProtKB/TrEMBL.
DT 23-NOV-2004, sequence version 1.
DT 27-MAR-2024, entry version 91.
DE SubName: Full=Thioesterase {ECO:0000313|EMBL:AAU28914.1};
GN OrderedLocusNames=lpg2867 {ECO:0000313|EMBL:AAU28914.1};
OS Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC
OS 33152 / DSM 7513).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Legionellales;
OC Legionellaceae; Legionella.
OX NCBI_TaxID=272624 {ECO:0000313|EMBL:AAU28914.1, ECO:0000313|Proteomes:UP000000609};
RN [1] {ECO:0000313|EMBL:AAU28914.1, ECO:0000313|Proteomes:UP000000609}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Philadelphia 1 / ATCC 33152 / DSM 7513
RC {ECO:0000313|Proteomes:UP000000609};
RX PubMed=15448271; DOI=10.1126/science.1099776;
RA Chien M., Morozova I., Shi S., Sheng H., Chen J., Gomez S.M., Asamani G.,
RA Hill K., Nuara J., Feder M., Rineer J., Greenberg J.J., Steshenko V.,
RA Park S.H., Zhao B., Teplitskaya E., Edwards J.R., Pampou S., Georghiou A.,
RA Chou I.C., Iannuccilli W., Ulz M.E., Kim D.H., Geringer-Sameth A.,
RA Goldsberry C., Morozov P., Fischer S.G., Segal G., Qu X., Rzhetsky A.,
RA Zhang P., Cayanis E., De Jong P.J., Ju J., Kalachikov S., Shuman H.A.,
RA Russo J.J.;
RT "The genomic sequence of the accidental pathogen Legionella pneumophila.";
RL Science 305:1966-1968(2004).
RN [2] {ECO:0007829|PDB:5BYU}
RP X-RAY CRYSTALLOGRAPHY (2.40 ANGSTROMS) IN COMPLEX WITH COENZYME A.
RA Swarbrick C.M.D., Forwood J.K.;
RT "Crystal structure of unnamed thioesterase Ipg2867 from Legionella
RT pneumophila.";
RL Submitted (JUN-2015) to the PDB data bank.
RN [3] {ECO:0007829|PDB:5DIO}
RP X-RAY CRYSTALLOGRAPHY (2.60 ANGSTROMS).
RA Swarbrick C.M.D., Forwood J.K.;
RT "Crystal structure of unnamed thioesterase lpg2867 from Legionella
RT pneumophila, the D21A mutant.";
RL Submitted (SEP-2015) to the PDB data bank.
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DR EMBL; AE017354; AAU28914.1; -; Genomic_DNA.
DR RefSeq; WP_010948553.1; NC_002942.5.
DR RefSeq; YP_096861.1; NC_002942.5.
DR PDB; 5BYU; X-ray; 2.40 A; A/B/C/D/E/F/G/H=1-130.
DR PDB; 5DIO; X-ray; 2.60 A; A/B=1-130.
DR PDBsum; 5BYU; -.
DR PDBsum; 5DIO; -.
DR AlphaFoldDB; Q5ZRL4; -.
DR SMR; Q5ZRL4; -.
DR STRING; 272624.lpg2867; -.
DR PaxDb; 272624-lpg2867; -.
DR GeneID; 66492038; -.
DR KEGG; lpn:lpg2867; -.
DR PATRIC; fig|272624.6.peg.3053; -.
DR eggNOG; COG0824; Bacteria.
DR HOGENOM; CLU_101141_2_2_6; -.
DR OrthoDB; 9799036at2; -.
DR Proteomes; UP000000609; Chromosome.
DR GO; GO:0016790; F:thiolester hydrolase activity; IEA:UniProt.
DR CDD; cd00586; 4HBT; 1.
DR Gene3D; 3.10.129.10; Hotdog Thioesterase; 1.
DR InterPro; IPR029069; HotDog_dom_sf.
DR PANTHER; PTHR31793; 4-HYDROXYBENZOYL-COA THIOESTERASE FAMILY MEMBER; 1.
DR PANTHER; PTHR31793:SF27; ACYL-ACYL CARRIER PROTEIN THIOESTERASE ATL1, CHLOROPLASTIC-RELATED; 1.
DR Pfam; PF13279; 4HBT_2; 1.
DR SUPFAM; SSF54637; Thioesterase/thiol ester dehydrase-isomerase; 1.
PE 1: Evidence at protein level;
KW 3D-structure {ECO:0007829|PDB:5BYU, ECO:0007829|PDB:5DIO};
KW Reference proteome {ECO:0000313|Proteomes:UP000000609}.
FT BINDING 25
FT /ligand="CoA"
FT /ligand_id="ChEBI:CHEBI:57287"
FT /ligand_label="1"
FT /evidence="ECO:0007829|PDB:5BYU"
FT BINDING 26
FT /ligand="CoA"
FT /ligand_id="ChEBI:CHEBI:57287"
FT /ligand_label="2"
FT /evidence="ECO:0007829|PDB:5BYU"
FT BINDING 58
FT /ligand="CoA"
FT /ligand_id="ChEBI:CHEBI:57287"
FT /ligand_label="2"
FT /evidence="ECO:0007829|PDB:5BYU"
FT BINDING 65
FT /ligand="CoA"
FT /ligand_id="ChEBI:CHEBI:57287"
FT /ligand_label="2"
FT /evidence="ECO:0007829|PDB:5BYU"
FT BINDING 65
FT /ligand="CoA"
FT /ligand_id="ChEBI:CHEBI:57287"
FT /ligand_label="1"
FT /evidence="ECO:0007829|PDB:5BYU"
FT BINDING 87
FT /ligand="CoA"
FT /ligand_id="ChEBI:CHEBI:57287"
FT /ligand_label="2"
FT /evidence="ECO:0007829|PDB:5BYU"
FT BINDING 87
FT /ligand="CoA"
FT /ligand_id="ChEBI:CHEBI:57287"
FT /ligand_label="1"
FT /evidence="ECO:0007829|PDB:5BYU"
FT BINDING 88
FT /ligand="CoA"
FT /ligand_id="ChEBI:CHEBI:57287"
FT /ligand_label="1"
FT /evidence="ECO:0007829|PDB:5BYU"
FT BINDING 88
FT /ligand="CoA"
FT /ligand_id="ChEBI:CHEBI:57287"
FT /ligand_label="2"
FT /evidence="ECO:0007829|PDB:5BYU"
FT BINDING 108
FT /ligand="CoA"
FT /ligand_id="ChEBI:CHEBI:57287"
FT /ligand_label="1"
FT /evidence="ECO:0007829|PDB:5BYU"
FT BINDING 108
FT /ligand="CoA"
FT /ligand_id="ChEBI:CHEBI:57287"
FT /ligand_label="2"
FT /evidence="ECO:0007829|PDB:5BYU"
FT BINDING 119
FT /ligand="CoA"
FT /ligand_id="ChEBI:CHEBI:57287"
FT /ligand_label="1"
FT /evidence="ECO:0007829|PDB:5BYU"
SQ SEQUENCE 130 AA; 14894 MW; F48902064103D2B5 CRC64;
MTEINKIIHK KTFDIAWGDM DALGHVNNAR YFDYFQEARI DWLRELDIKM TGQTGPVVIH
VACTFLKPIV YPATVTIHSK VNSLGNSSMI MDHDLYQEET LMAQGVSKIV WIDYTQNKSV
PLPDIIRNLV
//
