ID Q5ZVM6_LEGPH Unreviewed; 491 AA.
AC Q5ZVM6;
DT 23-NOV-2004, integrated into UniProtKB/TrEMBL.
DT 23-NOV-2004, sequence version 1.
DT 27-MAR-2024, entry version 120.
DE SubName: Full=Glycerol kinase {ECO:0000313|EMBL:AAU27496.1};
DE EC=2.7.1.30 {ECO:0000313|EMBL:AAU27496.1};
GN OrderedLocusNames=lpg1414 {ECO:0000313|EMBL:AAU27496.1};
OS Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC
OS 33152 / DSM 7513).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Legionellales;
OC Legionellaceae; Legionella.
OX NCBI_TaxID=272624 {ECO:0000313|EMBL:AAU27496.1, ECO:0000313|Proteomes:UP000000609};
RN [1] {ECO:0000313|EMBL:AAU27496.1, ECO:0000313|Proteomes:UP000000609}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Philadelphia 1 / ATCC 33152 / DSM 7513
RC {ECO:0000313|Proteomes:UP000000609};
RX PubMed=15448271; DOI=10.1126/science.1099776;
RA Chien M., Morozova I., Shi S., Sheng H., Chen J., Gomez S.M., Asamani G.,
RA Hill K., Nuara J., Feder M., Rineer J., Greenberg J.J., Steshenko V.,
RA Park S.H., Zhao B., Teplitskaya E., Edwards J.R., Pampou S., Georghiou A.,
RA Chou I.C., Iannuccilli W., Ulz M.E., Kim D.H., Geringer-Sameth A.,
RA Goldsberry C., Morozov P., Fischer S.G., Segal G., Qu X., Rzhetsky A.,
RA Zhang P., Cayanis E., De Jong P.J., Ju J., Kalachikov S., Shuman H.A.,
RA Russo J.J.;
RT "The genomic sequence of the accidental pathogen Legionella pneumophila.";
RL Science 305:1966-1968(2004).
CC -!- SIMILARITY: Belongs to the FGGY kinase family.
CC {ECO:0000256|ARBA:ARBA00009156}.
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DR EMBL; AE017354; AAU27496.1; -; Genomic_DNA.
DR RefSeq; WP_010947143.1; NC_002942.5.
DR RefSeq; YP_095443.1; NC_002942.5.
DR AlphaFoldDB; Q5ZVM6; -.
DR STRING; 272624.lpg1414; -.
DR PaxDb; 272624-lpg1414; -.
DR GeneID; 66490546; -.
DR KEGG; lpn:lpg1414; -.
DR PATRIC; fig|272624.6.peg.1484; -.
DR eggNOG; COG0554; Bacteria.
DR HOGENOM; CLU_009281_2_3_6; -.
DR OrthoDB; 9805576at2; -.
DR Proteomes; UP000000609; Chromosome.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0004370; F:glycerol kinase activity; IEA:UniProtKB-EC.
DR GO; GO:0006071; P:glycerol metabolic process; IEA:UniProtKB-KW.
DR GO; GO:0006072; P:glycerol-3-phosphate metabolic process; IEA:InterPro.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR CDD; cd07786; FGGY_EcGK_like; 1.
DR Gene3D; 3.30.420.40; -; 2.
DR InterPro; IPR043129; ATPase_NBD.
DR InterPro; IPR000577; Carb_kinase_FGGY.
DR InterPro; IPR018483; Carb_kinase_FGGY_CS.
DR InterPro; IPR018485; FGGY_C.
DR InterPro; IPR018484; FGGY_N.
DR InterPro; IPR005999; Glycerol_kin.
DR NCBIfam; TIGR01311; glycerol_kin; 1.
DR PANTHER; PTHR10196:SF78; GLYCEROL KINASE; 1.
DR PANTHER; PTHR10196; SUGAR KINASE; 1.
DR Pfam; PF02782; FGGY_C; 1.
DR Pfam; PF00370; FGGY_N; 1.
DR PIRSF; PIRSF000538; GlpK; 1.
DR SUPFAM; SSF53067; Actin-like ATPase domain; 2.
DR PROSITE; PS00933; FGGY_KINASES_1; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Glycerol metabolism {ECO:0000256|ARBA:ARBA00022798};
KW Kinase {ECO:0000313|EMBL:AAU27496.1};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000000609};
KW Transferase {ECO:0000313|EMBL:AAU27496.1}.
FT DOMAIN 3..245
FT /note="Carbohydrate kinase FGGY N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00370"
FT DOMAIN 255..442
FT /note="Carbohydrate kinase FGGY C-terminal"
FT /evidence="ECO:0000259|Pfam:PF02782"
SQ SEQUENCE 491 AA; 54593 MW; A4D30AA6FA0142B0 CRC64;
MNYILAIDQG TSSTRAMIYT LQGDLIANSQ YPLTQYYPNS GWVEHDPEEI WQKTLNAMRD
VVSQVQGKAI LCCGLTNQRE TTLIWNKKTG ECLAPAIVWQ DRRTEEFCYS LSEYSSMIQE
KTGLLPDPYF SASKLNWLLK NNAQAQSLIN QGDLAFGTID SFLIWRMTKG ASHATDITNA
SRTMLFNIHD EKWDKQLLEL FSISESVLPA VYSSDNHFGV IDKEWLGVEI PITGVAGDQQ
AALIGQGCFN GGMVKATFGT GGFLLLNTGD KPVFSKHKLL TTIAYKIKEK TVYGLEGSIY
HAGTTVKWLR DEMKLISHSA ETEVLARSLD SNNGVYLVSS FTGLGAPHWL SITGTAIIGV
SRSTNRAHFA RAALEGVCYQ TRDVLTCMRD DSQLDLTLLR ADGGMAVNQW FLQFMADQCQ
LTIQKPKDIE TTAKGAAVLA AIGSGLFDSV SSVNKIWDVE NEFQPFRERE VVEKDFRGWL
EALSMVKARH A
//
