ID Q63JX8_BURPS Unreviewed; 304 AA.
AC Q63JX8;
DT 25-OCT-2004, integrated into UniProtKB/TrEMBL.
DT 25-OCT-2004, sequence version 1.
DT 27-MAR-2024, entry version 106.
DE SubName: Full=LysR-family transcriptional regulator {ECO:0000313|EMBL:CAH39061.1};
GN OrderedLocusNames=BPSS1586 {ECO:0000313|EMBL:CAH39061.1};
OS Burkholderia pseudomallei (strain K96243).
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Burkholderiaceae; Burkholderia; pseudomallei group.
OX NCBI_TaxID=272560 {ECO:0000313|EMBL:CAH39061.1, ECO:0000313|Proteomes:UP000000605};
RN [1] {ECO:0000313|EMBL:CAH39061.1, ECO:0000313|Proteomes:UP000000605}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K96243 {ECO:0000313|EMBL:CAH39061.1,
RC ECO:0000313|Proteomes:UP000000605};
RX PubMed=15377794; DOI=10.1073/pnas.0403302101;
RA Holden M.T.G., Titball R.W., Peacock S.J., Cerdeno-Tarraga A.M., Atkins T.,
RA Crossman L.C., Pitt T., Churcher C., Mungall K., Bentley S.D., Sebaihia M.,
RA Thomson N.R., Bason N., Beacham I.R., Brooks K., Brown K.A., Brown N.F.,
RA Challis G.L., Cherevach I., Chillingworth T., Cronin A., Crosset B.,
RA Davis P., DeShazer D., Feltwell T., Fraser A., Hance Z., Hauser H.,
RA Holroyd S., Jagels K., Keith K.E., Maddison M., Moule S., Price C.,
RA Quail M.A., Rabbinowitsch E., Rutherford K., Sanders M., Simmonds M.,
RA Songsivilai S., Stevens K., Tumapa S., Vesaratchavest M., Whitehead S.,
RA Yeats C., Barrell B.G., Oyston P.C.F., Parkhill J.;
RT "Genomic plasticity of the causative agent of melioidosis, Burkholderia
RT pseudomallei.";
RL Proc. Natl. Acad. Sci. U.S.A. 101:14240-14245(2004).
CC -!- SIMILARITY: Belongs to the LysR transcriptional regulatory family.
CC {ECO:0000256|ARBA:ARBA00009437}.
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DR EMBL; BX571966; CAH39061.1; -; Genomic_DNA.
DR RefSeq; WP_004198844.1; NZ_CP009537.1.
DR RefSeq; YP_111594.1; NC_006351.1.
DR AlphaFoldDB; Q63JX8; -.
DR STRING; 272560.BPSS1586; -.
DR GeneID; 56597937; -.
DR KEGG; bps:BPSS1586; -.
DR PATRIC; fig|272560.51.peg.4964; -.
DR eggNOG; COG0583; Bacteria.
DR Proteomes; UP000000605; Chromosome 2.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR CDD; cd05466; PBP2_LTTR_substrate; 1.
DR Gene3D; 3.40.190.290; -; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR005119; LysR_subst-bd.
DR InterPro; IPR000847; Tscrpt_reg_HTH_LysR.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR30126:SF84; HTH-TYPE TRANSCRIPTIONAL ACTIVATOR BAUR; 1.
DR PANTHER; PTHR30126; HTH-TYPE TRANSCRIPTIONAL REGULATOR; 1.
DR Pfam; PF00126; HTH_1; 1.
DR Pfam; PF03466; LysR_substrate; 1.
DR PRINTS; PR00039; HTHLYSR.
DR SUPFAM; SSF53850; Periplasmic binding protein-like II; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS50931; HTH_LYSR; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000000605};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 8..65
FT /note="HTH lysR-type"
FT /evidence="ECO:0000259|PROSITE:PS50931"
SQ SEQUENCE 304 AA; 33213 MW; 65EE31431FC4FE83 CRC64;
MLGTLTDLDL RLIRVFVAVA DAGGVSAAQA TLNVSQPTIS TQLATLETRV GFRLCERGRS
GFRLTTKGER FYALAKKLYA AVDAFTGEAR HMDKTLVGTL AIGLIGHTPI SANARVSEAI
ARFRRRDEAV RFVISVRPPG DLEERLLSGD VQIAIGYFWH RVPALEYAPL FVERQLAYCG
RGHPLFARAG RLAAARVAAF EWAWRTYPSP EVALSTTPAN VTAHADNMEA IALLILSGHH
LGYLPRHFAA PYVEQGLLKA LNPATLCYDV TFDVVTRRGA RRDPIVQAFL DDLTHAHRGG
AAQA
//
