ID Q63SJ6_BURPS Unreviewed; 1297 AA.
AC Q63SJ6;
DT 25-OCT-2004, integrated into UniProtKB/TrEMBL.
DT 25-OCT-2004, sequence version 1.
DT 27-MAR-2024, entry version 117.
DE SubName: Full=ATP-dependent helicase {ECO:0000313|EMBL:CAH36327.1};
GN OrderedLocusNames=BPSL2324 {ECO:0000313|EMBL:CAH36327.1};
OS Burkholderia pseudomallei (strain K96243).
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Burkholderiaceae; Burkholderia; pseudomallei group.
OX NCBI_TaxID=272560 {ECO:0000313|EMBL:CAH36327.1, ECO:0000313|Proteomes:UP000000605};
RN [1] {ECO:0000313|EMBL:CAH36327.1, ECO:0000313|Proteomes:UP000000605}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K96243 {ECO:0000313|EMBL:CAH36327.1,
RC ECO:0000313|Proteomes:UP000000605};
RX PubMed=15377794; DOI=10.1073/pnas.0403302101;
RA Holden M.T.G., Titball R.W., Peacock S.J., Cerdeno-Tarraga A.M., Atkins T.,
RA Crossman L.C., Pitt T., Churcher C., Mungall K., Bentley S.D., Sebaihia M.,
RA Thomson N.R., Bason N., Beacham I.R., Brooks K., Brown K.A., Brown N.F.,
RA Challis G.L., Cherevach I., Chillingworth T., Cronin A., Crosset B.,
RA Davis P., DeShazer D., Feltwell T., Fraser A., Hance Z., Hauser H.,
RA Holroyd S., Jagels K., Keith K.E., Maddison M., Moule S., Price C.,
RA Quail M.A., Rabbinowitsch E., Rutherford K., Sanders M., Simmonds M.,
RA Songsivilai S., Stevens K., Tumapa S., Vesaratchavest M., Whitehead S.,
RA Yeats C., Barrell B.G., Oyston P.C.F., Parkhill J.;
RT "Genomic plasticity of the causative agent of melioidosis, Burkholderia
RT pseudomallei.";
RL Proc. Natl. Acad. Sci. U.S.A. 101:14240-14245(2004).
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; BX571965; CAH36327.1; -; Genomic_DNA.
DR RefSeq; YP_108920.1; NC_006350.1.
DR STRING; 272560.BPSL2324; -.
DR KEGG; bps:BPSL2324; -.
DR PATRIC; fig|272560.6.peg.2639; -.
DR eggNOG; COG1643; Bacteria.
DR Proteomes; UP000000605; Chromosome 1.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0003724; F:RNA helicase activity; IEA:InterPro.
DR CDD; cd18791; SF2_C_RHA; 1.
DR Gene3D; 1.20.120.1080; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR011709; DEAD-box_helicase_OB_fold.
DR InterPro; IPR048333; HA2_WH.
DR InterPro; IPR007502; Helicase-assoc_dom.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR024590; HrpA_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR010222; RNA_helicase_HrpA.
DR NCBIfam; TIGR01967; DEAH_box_HrpA; 1.
DR PANTHER; PTHR18934; ATP-DEPENDENT RNA HELICASE; 1.
DR PANTHER; PTHR18934:SF83; PRE-MRNA-SPLICING FACTOR ATP-DEPENDENT RNA HELICASE DHX16; 1.
DR Pfam; PF11898; DUF3418; 1.
DR Pfam; PF21010; HA2_C; 1.
DR Pfam; PF04408; HA2_N; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR Pfam; PF07717; OB_NTP_bind; 1.
DR SMART; SM00382; AAA; 1.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00847; HA2; 1.
DR SMART; SM00490; HELICc; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000313|EMBL:CAH36327.1};
KW Helicase {ECO:0000313|EMBL:CAH36327.1};
KW Hydrolase {ECO:0000313|EMBL:CAH36327.1};
KW Nucleotide-binding {ECO:0000313|EMBL:CAH36327.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000000605}.
FT DOMAIN 11..178
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 229..396
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
FT REGION 202..221
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1297 AA; 144420 MW; 4B9D6FDCCBCDB38B CRC64;
MPVSGKRDEI ARAIAAHPVV IVCGETGSGK TTQLPKICLA LGRGLGAGGA GLIGHTQPRR
LAASSTGRRI AEELGTPFGE VVGYKVRFTD NLAPGASVKL MTDGILLAET QTDPLLKAYD
TLIIDEAHER SLNIDFLLGY LRQILPRRPD LKLIVTSATI DAERFARHFG SDERPAPVIE
VSGRLYPVEV RYRPIADDRP AAVRHAEGAS SGRDRAKSAR EAERDLMDGI VDAVDELCRE
GPGDVLVFLP GEREIRDAAE ALRKHHPPHT EILPLFARLS AAEQERVFKA SNARRIVLAT
NVAETSLTVP GIRYVVDTGL ARVKRYSYRN KVEQLQIEPI SQAAANQRAG RCGRVADGVC
IRLYEESDFA GRARFTDPEI LRSSLASVIL RMKSLHLSAI ESFPFIEPPP GRAIADGYQL
LNELGAVDDE NALTPLGREL ARLPLDPRVG RMILAARDQQ ALREVLVIAS ALSVQDPRER
PVDAQEQADQ AHRRFADERS EFLQWLRIWA WFEEAVAHKK SNRQLVDACR QHFLSHLRLR
EWRDVHSQLL TVVREHGWRL NEADATFEQI HLSLLTGLLG NIGFKAEDEP HYLGARGIKF
HLWPGSALVK KAGRWVMAAE LVETSRLYAR CIAKIEPEWI ERIGAHLLKK SLSEPHWEKR
PAQVAAFERA TLYGLTIYHR RRVAFGRQDP ARARELFIRG ALVDGEFDTK LAFFAHNRKL
LADIEQLEHK SRRQDVLVDD ELIHAFYDQA IPAGIHTGAA FERWYRDEVS KSGQPEDKLR
LLYLSRDDLM RHEAAGVTTE LFPKRVTMAG VEMALAYHFE PGSPRDGVTL AVPLFALNQV
DARRAEWLVP GMLKEKAHLL LKSLPQKLRR HCVPLPEYAA GFVERAGRER FGAGGLVDAL
IADVREQTQV ATKTSDFKLE TLPAHLFMNF KVIDEHGRQL AMGRNLAQLR AELGAQAQQH
FQKIAAAATL APAGEPAAAA AGASGARARR VPLGAPPRAA EPAAQAGAAA GATALYENLT
TWNFGKLPEL LEIRRRGETL FGYPALVDRG THCDVEVFDS PDEAARIHRA GLRRLFALQL
KEPIKYLEKN LPGLREMAIQ YMSLGTQDEL RDQLIATALD RACLQEPLPA DDASFHARRD
EGRSRLNLLA QEIARLVGQI LAEYAGLAKK LAQAKPFPAA HADMQGQLAA LVGKRFVVDT
PYAQLAHFPR YLKGIALRID KLKADPARDA RQAAELQPLA QHYQRSVAQR GGVADARLAE
FRWLLEELRI SLFAQELRTP MPVSVKRLYK VWESMQR
//
