ID Q63WQ2_BURPS Unreviewed; 480 AA.
AC Q63WQ2;
DT 25-OCT-2004, integrated into UniProtKB/TrEMBL.
DT 25-OCT-2004, sequence version 1.
DT 27-MAR-2024, entry version 101.
DE SubName: Full=D-arabinitol 4-dehydrogenase {ECO:0000313|EMBL:CAH34831.1};
DE EC=1.1.1.11 {ECO:0000313|EMBL:CAH34831.1};
GN Name=dalD {ECO:0000313|EMBL:CAH34831.1};
GN OrderedLocusNames=BPSL0840 {ECO:0000313|EMBL:CAH34831.1};
OS Burkholderia pseudomallei (strain K96243).
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Burkholderiaceae; Burkholderia; pseudomallei group.
OX NCBI_TaxID=272560 {ECO:0000313|EMBL:CAH34831.1, ECO:0000313|Proteomes:UP000000605};
RN [1] {ECO:0000313|EMBL:CAH34831.1, ECO:0000313|Proteomes:UP000000605}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K96243 {ECO:0000313|EMBL:CAH34831.1,
RC ECO:0000313|Proteomes:UP000000605};
RX PubMed=15377794; DOI=10.1073/pnas.0403302101;
RA Holden M.T.G., Titball R.W., Peacock S.J., Cerdeno-Tarraga A.M., Atkins T.,
RA Crossman L.C., Pitt T., Churcher C., Mungall K., Bentley S.D., Sebaihia M.,
RA Thomson N.R., Bason N., Beacham I.R., Brooks K., Brown K.A., Brown N.F.,
RA Challis G.L., Cherevach I., Chillingworth T., Cronin A., Crosset B.,
RA Davis P., DeShazer D., Feltwell T., Fraser A., Hance Z., Hauser H.,
RA Holroyd S., Jagels K., Keith K.E., Maddison M., Moule S., Price C.,
RA Quail M.A., Rabbinowitsch E., Rutherford K., Sanders M., Simmonds M.,
RA Songsivilai S., Stevens K., Tumapa S., Vesaratchavest M., Whitehead S.,
RA Yeats C., Barrell B.G., Oyston P.C.F., Parkhill J.;
RT "Genomic plasticity of the causative agent of melioidosis, Burkholderia
RT pseudomallei.";
RL Proc. Natl. Acad. Sci. U.S.A. 101:14240-14245(2004).
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; BX571965; CAH34831.1; -; Genomic_DNA.
DR RefSeq; YP_107464.1; NC_006350.1.
DR AlphaFoldDB; Q63WQ2; -.
DR STRING; 272560.BPSL0840; -.
DR KEGG; bps:BPSL0840; -.
DR PATRIC; fig|272560.6.peg.905; -.
DR eggNOG; COG0246; Bacteria.
DR Proteomes; UP000000605; Chromosome 1.
DR GO; GO:0047813; F:D-arabinitol 4-dehydrogenase activity; IEA:UniProtKB-EC.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR008927; 6-PGluconate_DH-like_C_sf.
DR InterPro; IPR013328; 6PGD_dom2.
DR InterPro; IPR000669; Mannitol_DH.
DR InterPro; IPR013118; Mannitol_DH_C.
DR InterPro; IPR013131; Mannitol_DH_N.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR PANTHER; PTHR43362:SF7; D-MANNONATE OXIDOREDUCTASE; 1.
DR PANTHER; PTHR43362; MANNITOL DEHYDROGENASE DSF1-RELATED; 1.
DR Pfam; PF01232; Mannitol_dh; 1.
DR Pfam; PF08125; Mannitol_dh_C; 1.
DR PRINTS; PR00084; MTLDHDRGNASE.
DR SUPFAM; SSF48179; 6-phosphogluconate dehydrogenase C-terminal domain-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE 4: Predicted;
KW Oxidoreductase {ECO:0000313|EMBL:CAH34831.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000000605}.
FT DOMAIN 27..189
FT /note="Mannitol dehydrogenase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF01232"
FT DOMAIN 219..449
FT /note="Mannitol dehydrogenase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF08125"
SQ SEQUENCE 480 AA; 52115 MW; F265ADA6502DACF3 CRC64;
MIYTKFGGRE PAVRRHGMSS PSTAAPAILH IGVGSFHRAH QAWYLHRVNE ASPAAERWSL
VVGDIRDDLR ASREALAAQH GVYTLETVTP QGERAYETIR SIARVLPWSM ELAALVDAGA
APACRIVSFT VTEGGYYLDE HDRLDAANPD LAADLQGARL TIYGALAALL AERAARGAGP
LTLQSCDNLR NNGARFRAGM RAFLARRGLV ELLAWFDANV ACPSSMVDRI TPRPTPDVRE
RVRAATGFDD ACPVMGEAFI QWVIEDRFAA GRPAWEKAGA ELVDDVHPYE EAKIRILNAT
HSCIAWAGTL AGHSYIHEGT RDAHIRRFAH AYVTDDVIPC LTPSPLDLAR YRDVVLERFG
NPHIRDTNQR VAADGFSKIP GFIAPTLAES IARGVEPVST AVLPALFLRF LQRWAQGALP
YAYQDGVMDA RVARAIAGAA DPVAALAGER PLWGALAGMP ALERALRAGA ARVDAWLASR
//
