ID Q65JL6_BACLD Unreviewed; 377 AA.
AC Q65JL6; Q62V21;
DT 25-OCT-2004, integrated into UniProtKB/TrEMBL.
DT 25-OCT-2004, sequence version 1.
DT 27-MAR-2024, entry version 118.
DE RecName: Full=Flagellar motor switch protein FliN {ECO:0000256|RuleBase:RU362074};
GN Name=fliY {ECO:0000313|EMBL:AAU23388.1};
GN OrderedLocusNames=BL01261 {ECO:0000313|EMBL:AAU23388.1};
OS Bacillus licheniformis (strain ATCC 14580 / DSM 13 / JCM 2505 / CCUG 7422 /
OS NBRC 12200 / NCIMB 9375 / NCTC 10341 / NRRL NRS-1264 / Gibson 46).
OC Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Bacillus.
OX NCBI_TaxID=279010 {ECO:0000313|EMBL:AAU23388.1, ECO:0000313|Proteomes:UP000000606};
RN [1] {ECO:0000313|EMBL:AAU23388.1, ECO:0000313|Proteomes:UP000000606}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 14580 / DSM 13 / JCM 2505 / CCUG 7422 / NBRC 12200 / NCIMB
RC 9375 / NCTC 10341 / NRRL NRS-1264 / Gibson 46
RC {ECO:0000313|Proteomes:UP000000606};
RX PubMed=15461803; DOI=10.1186/gb-2004-5-10-r77;
RA Rey M.W., Ramaiya P., Nelson B.A., Brody-Karpin S.D., Zaretsky E.J.,
RA Tang M., Lopez de Leon A., Xiang H., Gusti V., Clausen I.G., Olsen P.B.,
RA Rasmussen M.D., Andersen J.T., Jorgensen P.L., Larsen T.S., Sorokin A.,
RA Bolotin A., Lapidus A., Galleron N., Ehrlich S.D., Berka R.M.;
RT "Complete genome sequence of the industrial bacterium Bacillus
RT licheniformis and comparisons with closely related Bacillus species.";
RL Genome Biol. 5:R77.1-R77.12(2004).
CC -!- FUNCTION: FliN is one of three proteins (FliG, FliN, FliM) that form
CC the rotor-mounted switch complex (C ring), located at the base of the
CC basal body. This complex interacts with the CheY and CheZ chemotaxis
CC proteins, in addition to contacting components of the motor that
CC determine the direction of flagellar rotation.
CC {ECO:0000256|RuleBase:RU362074}.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|RuleBase:RU362074};
CC Peripheral membrane protein {ECO:0000256|RuleBase:RU362074};
CC Cytoplasmic side {ECO:0000256|RuleBase:RU362074}. Bacterial flagellum
CC basal body {ECO:0000256|RuleBase:RU362074}. Membrane
CC {ECO:0000256|ARBA:ARBA00004287}; Peripheral membrane protein
CC {ECO:0000256|ARBA:ARBA00004287}; Cytoplasmic side
CC {ECO:0000256|ARBA:ARBA00004287}.
CC -!- SIMILARITY: Belongs to the FliN/MopA/SpaO family.
CC {ECO:0000256|ARBA:ARBA00009226, ECO:0000256|RuleBase:RU362074}.
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DR EMBL; CP000002; AAU23388.1; -; Genomic_DNA.
DR RefSeq; WP_003181794.1; NC_006322.1.
DR AlphaFoldDB; Q65JL6; -.
DR STRING; 279010.BL01261; -.
DR GeneID; 66216136; -.
DR KEGG; bli:BL01261; -.
DR PATRIC; fig|279010.13.peg.1852; -.
DR eggNOG; COG1776; Bacteria.
DR eggNOG; COG1886; Bacteria.
DR HOGENOM; CLU_033893_0_0_9; -.
DR Proteomes; UP000000606; Chromosome.
DR GO; GO:0009425; C:bacterial-type flagellum basal body; IEA:UniProtKB-SubCell.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0003774; F:cytoskeletal motor activity; IEA:UniProtKB-UniRule.
DR GO; GO:0016787; F:hydrolase activity; IEA:InterPro.
DR GO; GO:0071973; P:bacterial-type flagellum-dependent cell motility; IEA:UniProtKB-UniRule.
DR GO; GO:0006935; P:chemotaxis; IEA:UniProtKB-KW.
DR CDD; cd17907; FliY_FliN-Y; 1.
DR Gene3D; 3.40.1550.10; CheC-like; 1.
DR Gene3D; 2.30.330.10; SpoA-like; 1.
DR InterPro; IPR007597; CheC.
DR InterPro; IPR028976; CheC-like_sf.
DR InterPro; IPR012826; FliN.
DR InterPro; IPR001543; FliN-like_C.
DR InterPro; IPR001172; FliN_T3SS_HrcQb.
DR InterPro; IPR036429; SpoA-like_sf.
DR NCBIfam; TIGR02480; fliN; 1.
DR PANTHER; PTHR43484; -; 1.
DR PANTHER; PTHR43484:SF1; FLAGELLAR MOTOR SWITCH PROTEIN FLIN; 1.
DR Pfam; PF04509; CheC; 2.
DR Pfam; PF01052; FliMN_C; 1.
DR PRINTS; PR00956; FLGMOTORFLIN.
DR SUPFAM; SSF103039; CheC-like; 1.
DR SUPFAM; SSF101801; Surface presentation of antigens (SPOA); 1.
PE 3: Inferred from homology;
KW Bacterial flagellum {ECO:0000256|RuleBase:RU362074};
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475,
KW ECO:0000256|RuleBase:RU362074};
KW Cell projection {ECO:0000313|EMBL:AAU23388.1};
KW Chemotaxis {ECO:0000256|ARBA:ARBA00022500, ECO:0000256|RuleBase:RU362074};
KW Cilium {ECO:0000313|EMBL:AAU23388.1};
KW Flagellar rotation {ECO:0000256|ARBA:ARBA00022779,
KW ECO:0000256|RuleBase:RU362074}; Flagellum {ECO:0000313|EMBL:AAU23388.1};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU362074};
KW Reference proteome {ECO:0000313|Proteomes:UP000000606}.
FT DOMAIN 34..70
FT /note="CheC-like protein"
FT /evidence="ECO:0000259|Pfam:PF04509"
FT DOMAIN 131..166
FT /note="CheC-like protein"
FT /evidence="ECO:0000259|Pfam:PF04509"
FT DOMAIN 297..367
FT /note="Flagellar motor switch protein FliN-like C-terminal"
FT /evidence="ECO:0000259|Pfam:PF01052"
FT REGION 1..29
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 222..270
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 238..260
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 377 AA; 40819 MW; E120C4286F067F55 CRC64;
MENNNRLSQD EIDALLKGGD DTAQEQPESG LSLMEQDTIG EIGNISFGSS ATALSTLLNQ
KVEITTPTVS VIEKSHLNDE FPHPYVSIGV SYTEGFSGNN LLVIKQEDAA IIADLMMGGD
GTNADPSLGE IHLSAVQEAM NQMMGSAATS MSTVFSKKID ISPPEVDLLD VKEGEGTEQI
PKEDPLVKVS FRLKVGDLID SHIMQLYPLT FAKDLIDELT NQDGGEEPVK TEEVQTPVQE
KPAPNPNSAP AQTQRQEPAP KRQGTAKVSE PVQVAPAEFQ SFAPQTEAQP HLQNLDMLMD
IPLSVTVELG RTNRSVKEVL ELSTGSIIEL DKLAGEPVDI LVNQRVVAKG EVVVIDENFG
VRVTDILSQA ERISKLR
//
