ID Q65ME9_BACLD Unreviewed; 319 AA.
AC Q65ME9; Q62XU1;
DT 25-OCT-2004, integrated into UniProtKB/TrEMBL.
DT 25-OCT-2004, sequence version 1.
DT 27-MAR-2024, entry version 115.
DE RecName: Full=Magnesium transport protein CorA {ECO:0000256|RuleBase:RU362010};
GN Name=corA {ECO:0000256|RuleBase:RU362010,
GN ECO:0000313|EMBL:AAU22417.1};
GN OrderedLocusNames=BL03116 {ECO:0000313|EMBL:AAU22417.1};
OS Bacillus licheniformis (strain ATCC 14580 / DSM 13 / JCM 2505 / CCUG 7422 /
OS NBRC 12200 / NCIMB 9375 / NCTC 10341 / NRRL NRS-1264 / Gibson 46).
OC Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Bacillus.
OX NCBI_TaxID=279010 {ECO:0000313|EMBL:AAU22417.1, ECO:0000313|Proteomes:UP000000606};
RN [1] {ECO:0000313|EMBL:AAU22417.1, ECO:0000313|Proteomes:UP000000606}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 14580 / DSM 13 / JCM 2505 / CCUG 7422 / NBRC 12200 / NCIMB
RC 9375 / NCTC 10341 / NRRL NRS-1264 / Gibson 46
RC {ECO:0000313|Proteomes:UP000000606};
RX PubMed=15461803; DOI=10.1186/gb-2004-5-10-r77;
RA Rey M.W., Ramaiya P., Nelson B.A., Brody-Karpin S.D., Zaretsky E.J.,
RA Tang M., Lopez de Leon A., Xiang H., Gusti V., Clausen I.G., Olsen P.B.,
RA Rasmussen M.D., Andersen J.T., Jorgensen P.L., Larsen T.S., Sorokin A.,
RA Bolotin A., Lapidus A., Galleron N., Ehrlich S.D., Berka R.M.;
RT "Complete genome sequence of the industrial bacterium Bacillus
RT licheniformis and comparisons with closely related Bacillus species.";
RL Genome Biol. 5:R77.1-R77.12(2004).
CC -!- FUNCTION: Mediates influx of magnesium ions.
CC {ECO:0000256|RuleBase:RU362010}.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141,
CC ECO:0000256|RuleBase:RU362010}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141, ECO:0000256|RuleBase:RU362010}.
CC -!- SIMILARITY: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35)
CC family. {ECO:0000256|ARBA:ARBA00009765, ECO:0000256|RuleBase:RU362010}.
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DR EMBL; CP000002; AAU22417.1; -; Genomic_DNA.
DR RefSeq; WP_003179814.1; NC_006322.1.
DR AlphaFoldDB; Q65ME9; -.
DR STRING; 279010.BL03116; -.
DR GeneID; 66217030; -.
DR KEGG; bli:BL03116; -.
DR PATRIC; fig|279010.13.peg.821; -.
DR eggNOG; COG0598; Bacteria.
DR HOGENOM; CLU_007127_0_0_9; -.
DR Proteomes; UP000000606; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0015087; F:cobalt ion transmembrane transporter activity; IEA:UniProtKB-UniRule.
DR GO; GO:0015095; F:magnesium ion transmembrane transporter activity; IEA:UniProtKB-UniRule.
DR CDD; cd12831; TmCorA-like_u2; 1.
DR Gene3D; 3.30.460.20; CorA soluble domain-like; 1.
DR Gene3D; 1.20.58.340; Magnesium transport protein CorA, transmembrane region; 2.
DR InterPro; IPR045861; CorA_cytoplasmic_dom.
DR InterPro; IPR045863; CorA_TM1_TM2.
DR InterPro; IPR004488; Mg/Co-transport_prot_CorA.
DR InterPro; IPR002523; MgTranspt_CorA/ZnTranspt_ZntB.
DR NCBIfam; TIGR00383; corA; 1.
DR PANTHER; PTHR46494; CORA FAMILY METAL ION TRANSPORTER (EUROFUNG); 1.
DR PANTHER; PTHR46494:SF1; CORA FAMILY METAL ION TRANSPORTER (EUROFUNG); 1.
DR Pfam; PF01544; CorA; 1.
DR SUPFAM; SSF143865; CorA soluble domain-like; 1.
DR SUPFAM; SSF144083; Magnesium transport protein CorA, transmembrane region; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475,
KW ECO:0000256|RuleBase:RU362010};
KW Ion transport {ECO:0000256|RuleBase:RU362010};
KW Magnesium {ECO:0000256|RuleBase:RU362010};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU362010};
KW Reference proteome {ECO:0000313|Proteomes:UP000000606};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU362010};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|RuleBase:RU362010}; Transport {ECO:0000256|RuleBase:RU362010}.
FT TRANSMEM 253..277
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362010"
FT TRANSMEM 289..309
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362010"
SQ SEQUENCE 319 AA; 37912 MW; AFB2C50D33A8EE43 CRC64;
MIKHFAMTKD GRLLSDNKAE RLTDQDIEWF WTDFDQPSEE EVSLLKSHFH FHPLSVEDCV
HRLQRPKLDQ YEDYLFFVIH ALNQKTLASE EVDLFVGKDF IVTFHFHHSD GIEKVRRQLS
ENSELWKNGP GHIAYMVMDT LVDEYFPILY KIEDRLNEIA ESDSRKTYGT LMNEVFDIRG
DLLKLRKTII PMRDLLYRIL NIEISKENRE RKAYYSDIYD HLLKLAEIVE NNRDMTADLR
DSYQTLNSNR MNAIMMTLTI VSTIFIPLTF IAGVYGMNFD NMPELHWRYG YFFILGIMAA
VVAGMIFWFR HKGWFDIFK
//
