ID   Q65TX6_MANSM            Unreviewed;       416 AA.
AC   Q65TX6;
DT   25-OCT-2004, integrated into UniProtKB/TrEMBL.
DT   25-OCT-2004, sequence version 1.
DT   27-MAR-2024, entry version 94.
DE   RecName: Full=Aromatic amino acid permease {ECO:0000256|RuleBase:RU367149};
GN   Name=sdaC {ECO:0000313|EMBL:AAU37584.1};
GN   OrderedLocusNames=MS0977 {ECO:0000313|EMBL:AAU37584.1};
OS   Mannheimia succiniciproducens (strain MBEL55E).
OC   Bacteria; Pseudomonadota; Gammaproteobacteria; Pasteurellales;
OC   Pasteurellaceae; Basfia.
OX   NCBI_TaxID=221988 {ECO:0000313|EMBL:AAU37584.1, ECO:0000313|Proteomes:UP000000607};
RN   [1] {ECO:0000313|EMBL:AAU37584.1, ECO:0000313|Proteomes:UP000000607}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MBEL55E {ECO:0000313|EMBL:AAU37584.1,
RC   ECO:0000313|Proteomes:UP000000607};
RX   PubMed=15378067; DOI=10.1038/nbt1010;
RA   Hong S.H., Kim J.S., Lee S.Y., In Y.H., Choi S.S., Rih J.-K., Kim C.H.,
RA   Jeong H., Hur C.G., Kim J.J.;
RT   "The genome sequence of the capnophilic rumen bacterium Mannheimia
RT   succiniciproducens.";
RL   Nat. Biotechnol. 22:1275-1281(2004).
CC   -!- FUNCTION: Involved in transporting aromatic amino acids across the
CC       cytoplasmic membrane. {ECO:0000256|RuleBase:RU367149}.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane
CC       {ECO:0000256|ARBA:ARBA00004429, ECO:0000256|RuleBase:RU367149}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004429,
CC       ECO:0000256|RuleBase:RU367149}. Membrane
CC       {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC       {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the amino acid/polyamine transporter 2 family.
CC       Mtr/TnaB/TyrP permease subfamily. {ECO:0000256|RuleBase:RU367149}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AE016827; AAU37584.1; -; Genomic_DNA.
DR   AlphaFoldDB; Q65TX6; -.
DR   STRING; 221988.MS0977; -.
DR   KEGG; msu:MS0977; -.
DR   eggNOG; COG0814; Bacteria.
DR   HOGENOM; CLU_038102_3_0_6; -.
DR   Proteomes; UP000000607; Chromosome.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0015173; F:aromatic amino acid transmembrane transporter activity; IEA:UniProtKB-UniRule.
DR   Gene3D; 1.20.1740.10; Amino acid/polyamine transporter I; 1.
DR   InterPro; IPR018227; Amino_acid_transport_2.
DR   InterPro; IPR013059; Trp_tyr_transpt.
DR   NCBIfam; TIGR00837; araaP; 1.
DR   PANTHER; PTHR46997; LOW AFFINITY TRYPTOPHAN PERMEASE-RELATED; 1.
DR   PANTHER; PTHR46997:SF2; TYROSINE-SPECIFIC TRANSPORT SYSTEM; 1.
DR   Pfam; PF03222; Trp_Tyr_perm; 1.
DR   PRINTS; PR00166; AROAAPRMEASE.
PE   3: Inferred from homology;
KW   Amino-acid transport {ECO:0000256|ARBA:ARBA00022970,
KW   ECO:0000256|RuleBase:RU367149};
KW   Cell inner membrane {ECO:0000256|ARBA:ARBA00022519,
KW   ECO:0000256|RuleBase:RU367149};
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475,
KW   ECO:0000256|RuleBase:RU367149};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU367149};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW   ECO:0000256|RuleBase:RU367149};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|RuleBase:RU367149};
KW   Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|RuleBase:RU367149}.
FT   TRANSMEM        21..40
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU367149"
FT   TRANSMEM        46..68
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU367149"
FT   TRANSMEM        88..112
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU367149"
FT   TRANSMEM        132..153
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU367149"
FT   TRANSMEM        160..181
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU367149"
FT   TRANSMEM        193..214
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU367149"
FT   TRANSMEM        226..244
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU367149"
FT   TRANSMEM        289..310
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU367149"
FT   TRANSMEM        322..342
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU367149"
FT   TRANSMEM        348..371
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU367149"
FT   TRANSMEM        383..406
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU367149"
SQ   SEQUENCE   416 AA;  45007 MW;  89F795F6085607DB CRC64;
     MLHIILTLNR KFKMKNKTFG SALLVAGTTI GAGMLAMPLT SAEMGFTYTM ALLFLLWILL
     SYSALLFVEV YQTVQRKDAG IATLAEQYFG MVGRVLATLS LVIFMYAILS AYVTGGGSLL
     AGVLPFLGEH AAPISIIAFT VILGIFIVIS TGAVDGLTRL LFMIKLVAFV LVLTMMLPLV
     QGENLMAMPL KEFLIISASP VFFTSFGFHV IIPSINNYLD GNIKRLRAAI IGGTALPLVA
     YILWQMATHG VFPQAKFVEI INNDPTLNGL VDATYHVTGS NLISGSVRLF STLALVTSFL
     GVSLSLFDCL DDLLKRINIK AGRLALGVLT FLPPLAFALF YPEGFIAALG YAGQMFTFYG
     LVLPVGLAWR ARKLHPNLPY RVIGGNLTLL IALLLGLLIM NVPFLIEGGY LPKVIG
//