ID Q672J4_AEDAE Unreviewed; 148 AA.
AC Q672J4;
DT 11-OCT-2004, integrated into UniProtKB/TrEMBL.
DT 11-OCT-2004, sequence version 1.
DT 27-MAR-2024, entry version 135.
DE SubName: Full=Lysozyme {ECO:0000313|EMBL:AAU09087.1};
GN Name=110676294 {ECO:0000313|EnsemblMetazoa:AAEL003712-PA};
OS Aedes aegypti (Yellowfever mosquito) (Culex aegypti).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC Culicinae; Aedini; Aedes; Stegomyia.
OX NCBI_TaxID=7159 {ECO:0000313|EMBL:AAU09087.1};
RN [1] {ECO:0000313|EMBL:AAU09087.1}
RP NUCLEOTIDE SEQUENCE.
RA Ursic-Bedoya R.J., Mitzey A., Lowenberger C.;
RL Submitted (JUL-2004) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:AAU09087.1}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=15663778; DOI=10.1111/j.1365-2583.2004.00534.x;
RA Ursic Bedoya R.J., Mitzey A.M., Obraztsova M., Lowenberger C.;
RT "Molecular cloning and transcriptional activation of lysozyme-encoding
RT cDNAs in the mosquito Aedes aegypti.";
RL Insect Mol. Biol. 14:89-94(2005).
RN [3] {ECO:0000313|EnsemblMetazoa:AAEL003712-PA, ECO:0000313|Proteomes:UP000008820}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=LVP_AGWG {ECO:0000313|EnsemblMetazoa:AAEL003712-PA,
RC ECO:0000313|Proteomes:UP000008820};
RG Aedes aegypti Genome Working Group (AGWG);
RA Matthews B.J.;
RT "Aedes aegypti genome working group (AGWG) sequencing and assembly.";
RL Submitted (JUN-2017) to the EMBL/GenBank/DDBJ databases.
RN [4] {ECO:0000313|EnsemblMetazoa:AAEL003712-PA}
RP IDENTIFICATION.
RC STRAIN=LVP_AGWG {ECO:0000313|EnsemblMetazoa:AAEL003712-PA};
RG EnsemblMetazoa;
RL Submitted (FEB-2021) to UniProtKB.
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 22 family.
CC {ECO:0000256|RuleBase:RU004440}.
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DR EMBL; AY693973; AAU09087.1; -; mRNA.
DR RefSeq; XP_001664049.1; XM_001663999.2.
DR AlphaFoldDB; Q672J4; -.
DR CAZy; GH22; Glycoside Hydrolase Family 22.
DR PaxDb; 7159-AAEL003712-PA; -.
DR EnsemblMetazoa; AAEL003712-RA; AAEL003712-PA; AAEL003712.
DR VEuPathDB; VectorBase:AAEL003712; -.
DR eggNOG; ENOG502S1S1; Eukaryota.
DR HOGENOM; CLU_111620_2_0_1; -.
DR InParanoid; Q672J4; -.
DR OMA; TWCRRAK; -.
DR OrthoDB; 5361006at2759; -.
DR Proteomes; UP000008820; Chromosome 2.
DR GO; GO:0003796; F:lysozyme activity; IEA:InterPro.
DR CDD; cd16899; LYZ_C_invert; 1.
DR Gene3D; 1.10.530.10; -; 1.
DR InterPro; IPR001916; Glyco_hydro_22.
DR InterPro; IPR019799; Glyco_hydro_22_CS.
DR InterPro; IPR000974; Glyco_hydro_22_lys.
DR InterPro; IPR023346; Lysozyme-like_dom_sf.
DR PANTHER; PTHR11407:SF36; GEO02684P1-RELATED; 1.
DR PANTHER; PTHR11407; LYSOZYME C; 1.
DR Pfam; PF00062; Lys; 1.
DR PRINTS; PR00137; LYSOZYME.
DR PRINTS; PR00135; LYZLACT.
DR SMART; SM00263; LYZ1; 1.
DR SUPFAM; SSF53955; Lysozyme-like; 1.
DR PROSITE; PS00128; GLYCOSYL_HYDROL_F22_1; 1.
DR PROSITE; PS51348; GLYCOSYL_HYDROL_F22_2; 1.
PE 2: Evidence at transcript level;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Reference proteome {ECO:0000313|Proteomes:UP000008820};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..23
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 24..148
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5014310288"
FT DOMAIN 97..115
FT /note="Glycosyl hydrolases family 22 (GH22)"
FT /evidence="ECO:0000259|PROSITE:PS00128"
SQ SEQUENCE 148 AA; 16675 MW; AB4011778FB445D6 CRC64;
MGNAKLPIVL VGLFVLLAST IEAKKFDKCS LAKALLAQGF SKADLRNWVC LVQNESSMDT
NKKHNNSNGS TDWGLFQIND RYWCDPQDKK KKTSNECKVK CSEFLKSDIS KASTCAKKIY
KRHGFSAWYG WTNKCKGKVL PDLSKCKL
//
