ID Q67NT1_SYMTH Unreviewed; 660 AA.
AC Q67NT1;
DT 11-OCT-2004, integrated into UniProtKB/TrEMBL.
DT 11-OCT-2004, sequence version 1.
DT 27-MAR-2024, entry version 81.
DE RecName: Full=cellulose synthase (UDP-forming) {ECO:0000256|ARBA:ARBA00012539};
DE EC=2.4.1.12 {ECO:0000256|ARBA:ARBA00012539};
GN OrderedLocusNames=STH1677 {ECO:0000313|EMBL:BAD40662.1};
OS Symbiobacterium thermophilum (strain T / IAM 14863).
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Symbiobacteriaceae;
OC Symbiobacterium.
OX NCBI_TaxID=292459 {ECO:0000313|EMBL:BAD40662.1, ECO:0000313|Proteomes:UP000000417};
RN [1] {ECO:0000313|EMBL:BAD40662.1, ECO:0000313|Proteomes:UP000000417}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=T / IAM 14863 {ECO:0000313|Proteomes:UP000000417};
RX PubMed=15383646; DOI=10.1093/nar/gkh830;
RA Ueda K., Yamashita A., Ishikawa J., Shimada M., Watsuji T., Morimura K.,
RA Ikeda H., Hattori M., Beppu T.;
RT "Genome sequence of Symbiobacterium thermophilum, an uncultivable bacterium
RT that depends on microbial commensalism.";
RL Nucleic Acids Res. 32:4937-4944(2004).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; AP006840; BAD40662.1; -; Genomic_DNA.
DR RefSeq; WP_011195805.1; NC_006177.1.
DR AlphaFoldDB; Q67NT1; -.
DR STRING; 292459.STH1677; -.
DR KEGG; sth:STH1677; -.
DR eggNOG; COG1215; Bacteria.
DR HOGENOM; CLU_027872_0_0_9; -.
DR OrthoDB; 9768769at2; -.
DR Proteomes; UP000000417; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0016757; F:glycosyltransferase activity; IEA:UniProtKB-KW.
DR GO; GO:0030244; P:cellulose biosynthetic process; IEA:UniProtKB-KW.
DR InterPro; IPR001173; Glyco_trans_2-like.
DR InterPro; IPR029044; Nucleotide-diphossugar_trans.
DR PANTHER; PTHR43867; CELLULOSE SYNTHASE CATALYTIC SUBUNIT A [UDP-FORMING]; 1.
DR PANTHER; PTHR43867:SF2; CELLULOSE SYNTHASE CATALYTIC SUBUNIT A [UDP-FORMING]; 1.
DR Pfam; PF13632; Glyco_trans_2_3; 1.
DR SUPFAM; SSF53448; Nucleotide-diphospho-sugar transferases; 1.
PE 4: Predicted;
KW Cellulose biosynthesis {ECO:0000256|ARBA:ARBA00022916};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000000417};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 6..29
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 546..567
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 579..600
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 370..595
FT /note="Glycosyltransferase 2-like"
FT /evidence="ECO:0000259|Pfam:PF13632"
SQ SEQUENCE 660 AA; 73658 MW; FD63154362F958E2 CRC64;
MQLDTAAWVY LVAVGLHLFF FLLFLRLLWW KRYADTRYWK RRPALSLERV TARAREHGIA
LPRVSLIVPA RNEADVIERT VDHLAGLTYP PHLYEVLVVT DEKEAQAAAE SRTAAVTGAA
RALRGCADVP DPDTQAGGLI MALVAGLALD GIGEVSRRLG PNEGLRHLKR IPAPLLRPII
WDAACRLLRK GSRGVDHHVV RSLRSRLPGL GQEPLQRAYA ALLSLAIPCA VAFASLRGED
GAALGRRLAS LAAQAHHSLT RELILSLCTA LAANLTARLE ALAADPQLEQ RLADAYREVY
PTTQDIMERK VAEYSRRKDA PAVRHVVVPA DFDGRLGGRR LGVPVPSTKG RALNWALGFI
DGRSTWCGFY DAESRPDSRV LLYLAHRVVE ARAADVPLPR IFQGPVFQVR NWYDMGAFCK
LASLFTAISH EWHLPVVYRS IPFVGGTNVF VETRLLVEIG GFDSTTLTED LELGTRAWLK
ARAWPEYLPY PSSEQTPPTF MGFYRQRLRW ASGHIQVMRK IRAEGDGSPE QRRLLRSLWF
KGQGQWLFYQ AATLVPLTVL ILWALGLVDP TVLPPAWRYG LHMVSTVYIG FAVYIFLRYM
RYVDPASRPM MWLGQLGAVG QILVLPLAGF LFPVPYFSAL VLAAVGKGPS HWVKTPRTRE
//
