ID Q67RX4_SYMTH Unreviewed; 262 AA.
AC Q67RX4;
DT 11-OCT-2004, integrated into UniProtKB/TrEMBL.
DT 11-OCT-2004, sequence version 1.
DT 27-MAR-2024, entry version 93.
DE RecName: Full=2-oxoacid dehydrogenase acyltransferase catalytic domain-containing protein {ECO:0000259|Pfam:PF00198};
GN OrderedLocusNames=STH584 {ECO:0000313|EMBL:BAD39569.1};
OS Symbiobacterium thermophilum (strain T / IAM 14863).
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Symbiobacteriaceae;
OC Symbiobacterium.
OX NCBI_TaxID=292459 {ECO:0000313|EMBL:BAD39569.1, ECO:0000313|Proteomes:UP000000417};
RN [1] {ECO:0000313|EMBL:BAD39569.1, ECO:0000313|Proteomes:UP000000417}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=T / IAM 14863 {ECO:0000313|Proteomes:UP000000417};
RX PubMed=15383646; DOI=10.1093/nar/gkh830;
RA Ueda K., Yamashita A., Ishikawa J., Shimada M., Watsuji T., Morimura K.,
RA Ikeda H., Hattori M., Beppu T.;
RT "Genome sequence of Symbiobacterium thermophilum, an uncultivable bacterium
RT that depends on microbial commensalism.";
RL Nucleic Acids Res. 32:4937-4944(2004).
CC -!- COFACTOR:
CC Name=(R)-lipoate; Xref=ChEBI:CHEBI:83088;
CC Evidence={ECO:0000256|ARBA:ARBA00001938};
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DR EMBL; AP006840; BAD39569.1; -; Genomic_DNA.
DR RefSeq; WP_011194718.1; NC_006177.1.
DR AlphaFoldDB; Q67RX4; -.
DR STRING; 292459.STH584; -.
DR KEGG; sth:STH584; -.
DR eggNOG; COG0508; Bacteria.
DR HOGENOM; CLU_016733_2_1_9; -.
DR OrthoDB; 9805770at2; -.
DR Proteomes; UP000000417; Chromosome.
DR GO; GO:0016746; F:acyltransferase activity; IEA:InterPro.
DR Gene3D; 3.30.559.10; Chloramphenicol acetyltransferase-like domain; 1.
DR InterPro; IPR001078; 2-oxoacid_DH_actylTfrase.
DR InterPro; IPR023213; CAT-like_dom_sf.
DR PANTHER; PTHR43178; DIHYDROLIPOAMIDE ACETYLTRANSFERASE COMPONENT OF PYRUVATE DEHYDROGENASE COMPLEX; 1.
DR PANTHER; PTHR43178:SF5; LIPOAMIDE ACYLTRANSFERASE COMPONENT OF BRANCHED-CHAIN ALPHA-KETO ACID DEHYDROGENASE COMPLEX, MITOCHONDRIAL; 1.
DR Pfam; PF00198; 2-oxoacid_dh; 1.
DR SUPFAM; SSF52777; CoA-dependent acyltransferases; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000000417}.
FT DOMAIN 37..260
FT /note="2-oxoacid dehydrogenase acyltransferase catalytic"
FT /evidence="ECO:0000259|Pfam:PF00198"
FT REGION 1..21
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..15
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 262 AA; 27913 MW; 0BD185B92D0AC15C CRC64;
MQLFPSPPPG APAGLLLPGG TPDNPLAMGG PPFPPVVTLP LSHIRRVSML NLEQAQRTTA
PVTVVAEVDA TGLISVRESL KPLAERHLGI RLTYLPFFAA ATVRALKAWP IMNAMLTPQG
FVIPRYINLG IATAVPGGVL LPVVPGAERM GFWDLARAIH LQTQKARAGL LSPHELSGHT
FVITNTGRYG ATLFGTPIIQ PPNVGILAFE AIQKRPVVVG DDQLAIRPMM YLALTADHRA
VDGAEMIGFL ATVKEALEQV AL
//
