ID Q6A590_CAEEL Unreviewed; 552 AA.
AC Q6A590;
DT 13-SEP-2004, integrated into UniProtKB/TrEMBL.
DT 13-SEP-2004, sequence version 1.
DT 27-MAR-2024, entry version 132.
DE SubName: Full=F-box domain-containing protein {ECO:0000313|EMBL:CCD69938.1};
GN ORFNames=CELE_T28B4.1 {ECO:0000313|EMBL:CCD69938.1}, T28B4.1
GN {ECO:0000313|EMBL:CCD69938.1, ECO:0000313|WormBase:T28B4.1c};
OS Caenorhabditis elegans.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC Caenorhabditis.
OX NCBI_TaxID=6239 {ECO:0000313|EMBL:CCD69938.1, ECO:0000313|Proteomes:UP000001940};
RN [1] {ECO:0000313|EMBL:CCD69938.1, ECO:0000313|Proteomes:UP000001940}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Bristol N2 {ECO:0000313|EMBL:CCD69938.1,
RC ECO:0000313|Proteomes:UP000001940};
RX PubMed=9851916; DOI=10.1126/science.282.5396.2012;
RG The C. elegans sequencing consortium;
RA Sulson J.E., Waterston R.;
RT "Genome sequence of the nematode C. elegans: a platform for investigating
RT biology.";
RL Science 282:2012-2018(1998).
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DR EMBL; BX284606; CCD69938.1; -; Genomic_DNA.
DR RefSeq; NP_001024931.1; NM_001029760.2.
DR AlphaFoldDB; Q6A590; -.
DR SMR; Q6A590; -.
DR STRING; 6239.T28B4.1c.1; -.
DR PaxDb; 6239-T28B4-1c; -.
DR EnsemblMetazoa; T28B4.1c.1; T28B4.1c.1; WBGene00020884.
DR GeneID; 180930; -.
DR KEGG; cel:CELE_T28B4.1; -.
DR UCSC; T28B4.1c; c. elegans.
DR AGR; WB:WBGene00020884; -.
DR WormBase; T28B4.1c; CE37154; WBGene00020884; -.
DR eggNOG; KOG1947; Eukaryota.
DR GeneTree; ENSGT00510000053582; -.
DR InParanoid; Q6A590; -.
DR OMA; AKIHIDQ; -.
DR OrthoDB; 840819at2759; -.
DR PhylomeDB; Q6A590; -.
DR Proteomes; UP000001940; Chromosome X.
DR Bgee; WBGene00020884; Expressed in larva and 3 other cell types or tissues.
DR ExpressionAtlas; Q6A590; baseline.
DR GO; GO:0031398; P:positive regulation of protein ubiquitination; IBA:GO_Central.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 3.
DR InterPro; IPR036047; F-box-like_dom_sf.
DR InterPro; IPR001810; F-box_dom.
DR InterPro; IPR032675; LRR_dom_sf.
DR PANTHER; PTHR20933:SF4; F-BOX INVOLVED IN POLYQ PATHOGENESIS, ISOFORM A; 1.
DR PANTHER; PTHR20933; F-BOX ONLY PROTEIN 33; 1.
DR Pfam; PF12937; F-box-like; 1.
DR SMART; SM00256; FBOX; 1.
DR SUPFAM; SSF81383; F-box domain; 1.
DR SUPFAM; SSF52047; RNI-like; 1.
DR PROSITE; PS50181; FBOX; 1.
PE 1: Evidence at protein level;
KW Proteomics identification {ECO:0007829|EPD:Q6A590,
KW ECO:0007829|PeptideAtlas:Q6A590};
KW Reference proteome {ECO:0000313|Proteomes:UP000001940}.
FT DOMAIN 63..109
FT /note="F-box"
FT /evidence="ECO:0000259|PROSITE:PS50181"
SQ SEQUENCE 552 AA; 64201 MW; 112FBB5564314313 CRC64;
MLDLFRSKGE AKVSEHASTS SNTWLAKKKH FRDTEEWKVK KTRILNKLRA LSKINLALVL
SRMPTIEKLP DKVLRDIFQY LSPKQINQVG LVCKRWRVTS QNPLLWKFVS FRPNYGGIQV
NPQCIDHFIQ LIGTRFSELR IVELATDLIT PNVLYELANK APKLQYLTLD FSTAMQLHDF
TDLQSFPSRL KSLTLCLSEN IFLEGFLRKV YTFISSVETL HIIGTYEKVE DEEEEVYETV
NVFKLKQFLP NLRVVNLWGV PFITDEHVDA ISSNCAHLEC LCVNYCPKVT GSCLKLVLQR
CRKLKTLFLA HTKLDNNIVK MVDWEKTRIE ELDIKGTELN SDALISILTR LPHLRWLDAS
WLECMTDQVL EAWQNSNAMG SLQFLNMDTC DSINEQALVD MIKRHGHQFH GLCLGGQHKL
LEYFWMNMIP QLRNIRVMVM GIAEDCCPKV VAKIHVDQFV DCIAQNCPRL TRLEVRWDDE
TLRFSDKSSK FIDVLRMKCL MLHSIVLSDG QYYELVRSNF ERADRMSVVR TTEMCRTGLL
HCSRYFNKLL FN
//
