ID Q6BFH6_PARTE Unreviewed; 794 AA.
AC Q6BFH6;
DT 16-AUG-2004, integrated into UniProtKB/TrEMBL.
DT 16-AUG-2004, sequence version 1.
DT 27-MAR-2024, entry version 98.
DE SubName: Full=Chromosome undetermined scaffold_1, whole genome shotgun sequence {ECO:0000313|EMBL:CAK55656.1};
DE SubName: Full=Tubulin-tyrosine ligase, putative {ECO:0000313|EMBL:CAH03594.1};
GN ORFNames=GSPATT00000091001 {ECO:0000313|EMBL:CAK55656.1}, PTMB.397c
GN {ECO:0000313|EMBL:CAH03594.1};
OS Paramecium tetraurelia.
OC Eukaryota; Sar; Alveolata; Ciliophora; Intramacronucleata;
OC Oligohymenophorea; Peniculida; Parameciidae; Paramecium.
OX NCBI_TaxID=5888 {ECO:0000313|EMBL:CAH03594.1, ECO:0000313|Proteomes:UP000000600};
RN [1] {ECO:0000313|EMBL:CAH03594.1, ECO:0000313|Proteomes:UP000000600}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Stock d4-2 {ECO:0000313|EMBL:CAH03594.1,
RC ECO:0000313|Proteomes:UP000000600};
RX PubMed=15296759; DOI=10.1016/j.cub.2004.07.029;
RA Zagulski M., Nowak J.K., Le Mouel A., Nowacki M., Migdalski A.,
RA Gromadka R., Noel B., Blanc I., Dessen P., Wincker P., Keller A.M.,
RA Cohen J., Meyer E., Sperling L.;
RT "High coding density on the largest Paramecium tetraurelia somatic
RT chromosome.";
RL Curr. Biol. 14:1397-1404(2004).
RN [2] {ECO:0000313|EMBL:CAK55656.1, ECO:0000313|Proteomes:UP000000600}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Stock d4-2 {ECO:0000313|EMBL:CAK55656.1,
RC ECO:0000313|Proteomes:UP000000600};
RX PubMed=17086204; DOI=10.1038/nature05230;
RG Genoscope;
RA Aury J.-M., Jaillon O., Duret L., Noel B., Jubin C., Porcel B.M.,
RA Segurens B., Daubin V., Anthouard V., Aiach N., Arnaiz O., Billaut A.,
RA Beisson J., Blanc I., Bouhouche K., Camara F., Duharcourt S., Guigo R.,
RA Gogendeau D., Katinka M., Keller A.-M., Kissmehl R., Klotz C., Koll F.,
RA Le Moue A., Lepere C., Malinsky S., Nowacki M., Nowak J.K., Plattner H.,
RA Poulain J., Ruiz F., Serrano V., Zagulski M., Dessen P., Betermier M.,
RA Weissenbach J., Scarpelli C., Schachter V., Sperling L., Meyer E.,
RA Cohen J., Wincker P.;
RT "Global trends of whole-genome duplications revealed by the ciliate
RT Paramecium tetraurelia.";
RL Nature 444:171-178(2006).
RN [3] {ECO:0000313|EMBL:CAK55656.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Stock d4-2 {ECO:0000313|EMBL:CAK55656.1};
RG Genoscope;
RL Submitted (MAR-2006) to the EMBL/GenBank/DDBJ databases.
RN [4] {ECO:0000313|EMBL:CAH03594.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Stock d4-2 {ECO:0000313|EMBL:CAH03594.1};
RA Nowak J.K., Migdalski A., Gromadka R., Zagulski M.;
RT "Paramecium megabase sequencing project.";
RL Submitted (NOV-2006) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; CR548612; CAH03594.1; -; Genomic_DNA.
DR EMBL; CT867985; CAK55656.1; -; Genomic_DNA.
DR RefSeq; XP_001347221.1; XM_001347185.1.
DR RefSeq; XP_001423054.1; XM_001423017.1.
DR AlphaFoldDB; Q6BFH6; -.
DR STRING; 5888.Q6BFH6; -.
DR EnsemblProtists; CAK55656; CAK55656; GSPATT00000091001.
DR GeneID; 5008815; -.
DR GeneID; 79574086; -.
DR KEGG; ptm:GSPATT00000091001; -.
DR KEGG; ptm:PTMB.397c; -.
DR eggNOG; KOG2157; Eukaryota.
DR HOGENOM; CLU_016075_0_0_1; -.
DR InParanoid; Q6BFH6; -.
DR Proteomes; UP000000600; Chromosome.
DR Proteomes; UP000000600; Partially assembled WGS sequence.
DR GO; GO:0016874; F:ligase activity; IEA:UniProtKB-KW.
DR GO; GO:0036211; P:protein modification process; IEA:InterPro.
DR Gene3D; 3.30.470.20; ATP-grasp fold, B domain; 1.
DR InterPro; IPR004344; TTL/TTLL_fam.
DR PANTHER; PTHR46069:SF1; LIGASE, PUTATIVE-RELATED; 1.
DR PANTHER; PTHR46069; TUBULIN TYROSINE LIGASE; 1.
DR Pfam; PF03133; TTL; 1.
DR SUPFAM; SSF56059; Glutathione synthetase ATP-binding domain-like; 1.
DR PROSITE; PS51221; TTL; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils}; Ligase {ECO:0000313|EMBL:CAH03594.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000000600}.
FT REGION 772..794
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 128..155
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 777..794
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 794 AA; 94753 MW; 0C762CD8D311F4D8 CRC64;
MQRDLAIFPN TPQLQGLFNP TPIHPMTAFV ARSCYKYNQL QRNKQQRIVI QHIPQKLRPN
EKRHISLPRA LQAIKKQQFE SLRRSSHQKD QSYSLVFSEF KQEELILSNI DKFYNMQNKL
QTSNDDLVEE RKANLKELKR SNSKMKNALE NDKTKLILQN ILGGMQQKVN EVAHENHMRI
MGMQIKKFKL QDQQSIRNKA WSQEKERESS KSFVEKRDFN TRSVQKKRYQ SPQTKIKNIS
QQAMKTNQNF RFSLTDYSSL SREQLFQMKL LSYHYLIFIV ASQSNFYVQP SEGVIELKFK
VGKGNNSLLI KELFKSRWWW NLNQEAEYKE LNFIWTQIKV PQFMNLQEWS KDPSINRLKS
LSSTFADLKR QKKQKSPKSN KQIQKFGTFD DPIKKLIVEQ DVNELKSMDK SIQSFIKYAE
KKELKIIENV NKIHNHIERN YHLGNKKAMF HNMKKYYELT KQELSLHLPM TFHVSGTKDK
QYQQFMEYYK QKKGNNIWIV KPGEFTNRGN GIIVCQSLAE IHKIVSKKQV HPNGKPFTYL
IQKYIEKPFL YNKRKFDIRC YFLITQLNSI IRAYWYEEGY IRTSSEEFDI KDVSNQYVHL
TNDAIQKYSE AYGKYENGNK LSFAEFQRYL DKWHSNDHLN FYKDLYPELK IITLNAIKSV
YHKIEPYKRN YNFEIFGLDF MIDEKFQPYL IEINTNPCLE LSSPLLGRII PAMVENAFRL
SIDTLIPPPE QSTWPPNKKH LLFYDNMLEN NRFQLIFDER EDAQELNVLY SNQLNDDQTD
EMDEEEEEYQ SDAD
//
