ID Q6BZV8_YARLI Unreviewed; 716 AA.
AC Q6BZV8;
DT 16-AUG-2004, integrated into UniProtKB/TrEMBL.
DT 16-AUG-2004, sequence version 1.
DT 24-JAN-2024, entry version 98.
DE RecName: Full=polynucleotide adenylyltransferase {ECO:0000256|ARBA:ARBA00012388};
DE EC=2.7.7.19 {ECO:0000256|ARBA:ARBA00012388};
GN ORFNames=YALI0_F30525g {ECO:0000313|EMBL:CAG78867.1};
OS Yarrowia lipolytica (strain CLIB 122 / E 150) (Yeast) (Candida lipolytica).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Dipodascaceae; Yarrowia.
OX NCBI_TaxID=284591 {ECO:0000313|EMBL:CAG78867.1, ECO:0000313|Proteomes:UP000001300};
RN [1] {ECO:0000313|EMBL:CAG78867.1, ECO:0000313|Proteomes:UP000001300}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CLIB 122 / E 150 {ECO:0000313|Proteomes:UP000001300};
RX PubMed=15229592; DOI=10.1038/nature02579;
RG Genolevures;
RA Dujon B., Sherman D., Fischer G., Durrens P., Casaregola S., Lafontaine I.,
RA de Montigny J., Marck C., Neuveglise C., Talla E., Goffard N., Frangeul L.,
RA Aigle M., Anthouard V., Babour A., Barbe V., Barnay S., Blanchin S.,
RA Beckerich J.M., Beyne E., Bleykasten C., Boisrame A., Boyer J.,
RA Cattolico L., Confanioleri F., de Daruvar A., Despons L., Fabre E.,
RA Fairhead C., Ferry-Dumazet H., Groppi A., Hantraye F., Hennequin C.,
RA Jauniaux N., Joyet P., Kachouri R., Kerrest A., Koszul R., Lemaire M.,
RA Lesur I., Ma L., Muller H., Nicaud J.M., Nikolski M., Oztas S.,
RA Ozier-Kalogeropoulos O., Pellenz S., Potier S., Richard G.F., Straub M.L.,
RA Suleau A., Swennene D., Tekaia F., Wesolowski-Louvel M., Westhof E.,
RA Wirth B., Zeniou-Meyer M., Zivanovic I., Bolotin-Fukuhara M., Thierry A.,
RA Bouchier C., Caudron B., Scarpelli C., Gaillardin C., Weissenbach J.,
RA Wincker P., Souciet J.L.;
RT "Genome evolution in yeasts.";
RL Nature 430:35-44(2004).
CC -!- SIMILARITY: Belongs to the DNA polymerase type-B-like family.
CC {ECO:0000256|ARBA:ARBA00008593}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CR382132; CAG78867.1; -; Genomic_DNA.
DR RefSeq; XP_506054.1; XM_506054.1.
DR AlphaFoldDB; Q6BZV8; -.
DR STRING; 284591.Q6BZV8; -.
DR EnsemblFungi; CAG78867; CAG78867; YALI0_F30525g.
DR GeneID; 2907644; -.
DR KEGG; yli:YALI0F30525g; -.
DR VEuPathDB; FungiDB:YALI0_F30525g; -.
DR HOGENOM; CLU_013572_5_0_1; -.
DR InParanoid; Q6BZV8; -.
DR OMA; ICMVYSF; -.
DR OrthoDB; 21395at2759; -.
DR Proteomes; UP000001300; Chromosome F.
DR GO; GO:0005730; C:nucleolus; IBA:GO_Central.
DR GO; GO:0031499; C:TRAMP complex; IBA:GO_Central.
DR GO; GO:1990817; F:poly(A) RNA polymerase activity; IEA:UniProtKB-EC.
DR GO; GO:0031123; P:RNA 3'-end processing; IBA:GO_Central.
DR CDD; cd05402; NT_PAP_TUTase; 1.
DR Gene3D; 1.10.1410.10; -; 1.
DR Gene3D; 3.30.460.10; Beta Polymerase, domain 2; 1.
DR InterPro; IPR043519; NT_sf.
DR InterPro; IPR002058; PAP_assoc.
DR InterPro; IPR002934; Polymerase_NTP_transf_dom.
DR InterPro; IPR045862; Trf4-like.
DR PANTHER; PTHR23092:SF15; INACTIVE NON-CANONICAL POLY(A) RNA POLYMERASE PROTEIN TRF4-2-RELATED; 1.
DR PANTHER; PTHR23092; POLY(A) RNA POLYMERASE; 1.
DR Pfam; PF01909; NTP_transf_2; 1.
DR Pfam; PF03828; PAP_assoc; 1.
DR SUPFAM; SSF81301; Nucleotidyltransferase; 1.
DR SUPFAM; SSF81631; PAP/OAS1 substrate-binding domain; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000001300}.
FT DOMAIN 275..369
FT /note="Polymerase nucleotidyl transferase"
FT /evidence="ECO:0000259|Pfam:PF01909"
FT DOMAIN 441..499
FT /note="PAP-associated"
FT /evidence="ECO:0000259|Pfam:PF03828"
FT REGION 1..229
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 588..716
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 36..62
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 63..77
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 91..109
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 113..130
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 131..157
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 158..178
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 203..224
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 588..675
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 685..706
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 716 AA; 79437 MW; F187A72C6A43FCC8 CRC64;
MFSEVLSPMA KRTTKLPPAT VATKADLRNR PIAQPVSRRR GQQATPNNAN NNSNNNSAED
KSNNTNDTKD SKDGKEKASK KKRKKNKKKS QSGPISPQDR RNSGNGYNVL VDENDDKSGD
EGERSSKKRR TAGSAASTTA SSDMDSENER SVSTAPTSAP APKPPADSPP PPPPVDPSEW
NMNEDFVGFD FSDGEDEEDE EPEEPVRSRK RTIEEVDDAS SGPASKKQDL EAPWIKSNYH
QYDRVSDWLQ EEVMDFVKYI SPTQSEIKAR QDLVERVRGA VNGLWGDAKV HVLGSFTTNM
HLPQSDIDLV VCSPHGHYGE RACIYQLSSV IRSRMKVAEL QTITKARVPI IKFIDSRTGV
HVDISFEKDG GIKTASTITK WSKSMPALRP LVLIVKQFLS SRRLNEVFTG GLGGFSVICM
VYSFLIQHPR ISTGDISPMD NLGVLLIEFF ELYGVNFNYE RVALNMDGNC GYLSKRLYPD
LIGRNPFAVA IRDPDDHENN ISQGTFNMRN IKRAFSGAFQ LLSGKCLDMN KTGYKGRQGK
SLLTSIIKLK GPVRDQTPDA ITEPLKYTGG GDEFKIPQDA VYNSVLMNDE DEDEKAKQAE
DADKTKRRAA QREEQKKKKE LTTASDDKIP KGPAADRNQP KADQRKMSKD RAAARAAARE
VMEISSDDDD GSDSKNGGAK SNPIDLSSDE EKGRSDIKKD PSAKRRFWQQ KGGLDY
//
