ID   Q6C0I8_YARLI            Unreviewed;       356 AA.
AC   Q6C0I8;
DT   16-AUG-2004, integrated into UniProtKB/TrEMBL.
DT   16-AUG-2004, sequence version 1.
DT   27-MAR-2024, entry version 101.
DE   RecName: Full=Translation initiation factor eIF2B subunit beta {ECO:0000256|ARBA:ARBA00044122};
DE   AltName: Full=eIF2B GDP-GTP exchange factor subunit beta {ECO:0000256|ARBA:ARBA00044228};
GN   ORFNames=YALI0_F24321g {ECO:0000313|EMBL:CAG78635.1};
OS   Yarrowia lipolytica (strain CLIB 122 / E 150) (Yeast) (Candida lipolytica).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Dipodascaceae; Yarrowia.
OX   NCBI_TaxID=284591 {ECO:0000313|EMBL:CAG78635.1, ECO:0000313|Proteomes:UP000001300};
RN   [1] {ECO:0000313|EMBL:CAG78635.1, ECO:0000313|Proteomes:UP000001300}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CLIB 122 / E 150 {ECO:0000313|Proteomes:UP000001300};
RX   PubMed=15229592; DOI=10.1038/nature02579;
RG   Genolevures;
RA   Dujon B., Sherman D., Fischer G., Durrens P., Casaregola S., Lafontaine I.,
RA   de Montigny J., Marck C., Neuveglise C., Talla E., Goffard N., Frangeul L.,
RA   Aigle M., Anthouard V., Babour A., Barbe V., Barnay S., Blanchin S.,
RA   Beckerich J.M., Beyne E., Bleykasten C., Boisrame A., Boyer J.,
RA   Cattolico L., Confanioleri F., de Daruvar A., Despons L., Fabre E.,
RA   Fairhead C., Ferry-Dumazet H., Groppi A., Hantraye F., Hennequin C.,
RA   Jauniaux N., Joyet P., Kachouri R., Kerrest A., Koszul R., Lemaire M.,
RA   Lesur I., Ma L., Muller H., Nicaud J.M., Nikolski M., Oztas S.,
RA   Ozier-Kalogeropoulos O., Pellenz S., Potier S., Richard G.F., Straub M.L.,
RA   Suleau A., Swennene D., Tekaia F., Wesolowski-Louvel M., Westhof E.,
RA   Wirth B., Zeniou-Meyer M., Zivanovic I., Bolotin-Fukuhara M., Thierry A.,
RA   Bouchier C., Caudron B., Scarpelli C., Gaillardin C., Weissenbach J.,
RA   Wincker P., Souciet J.L.;
RT   "Genome evolution in yeasts.";
RL   Nature 430:35-44(2004).
CC   -!- SUBCELLULAR LOCATION: Cytoplasm, cytosol
CC       {ECO:0000256|ARBA:ARBA00004514}.
CC   -!- SIMILARITY: Belongs to the eIF-2B alpha/beta/delta subunits family.
CC       {ECO:0000256|ARBA:ARBA00007251, ECO:0000256|RuleBase:RU003814}.
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DR   EMBL; CR382132; CAG78635.1; -; Genomic_DNA.
DR   RefSeq; XP_505824.1; XM_505824.1.
DR   AlphaFoldDB; Q6C0I8; -.
DR   STRING; 284591.Q6C0I8; -.
DR   EnsemblFungi; CAG78635; CAG78635; YALI0_F24321g.
DR   GeneID; 2908723; -.
DR   KEGG; yli:YALI0F24321g; -.
DR   VEuPathDB; FungiDB:YALI0_F24321g; -.
DR   HOGENOM; CLU_016218_4_3_1; -.
DR   InParanoid; Q6C0I8; -.
DR   OMA; SHSCAVA; -.
DR   OrthoDB; 169494at2759; -.
DR   Proteomes; UP000001300; Chromosome F.
DR   GO; GO:0005851; C:eukaryotic translation initiation factor 2B complex; IBA:GO_Central.
DR   GO; GO:0032045; C:guanyl-nucleotide exchange factor complex; IEA:EnsemblFungi.
DR   GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:EnsemblFungi.
DR   GO; GO:0003743; F:translation initiation factor activity; IBA:GO_Central.
DR   GO; GO:0002183; P:cytoplasmic translational initiation; IEA:EnsemblFungi.
DR   GO; GO:0006446; P:regulation of translational initiation; IEA:EnsemblFungi.
DR   GO; GO:0006413; P:translational initiation; IBA:GO_Central.
DR   InterPro; IPR000649; IF-2B-related.
DR   InterPro; IPR042529; IF_2B-like_C.
DR   InterPro; IPR037171; NagB/RpiA_transferase-like.
DR   PANTHER; PTHR45859; TRANSLATION INITIATION FACTOR EIF-2B SUBUNIT BETA; 1.
DR   PANTHER; PTHR45859:SF1; TRANSLATION INITIATION FACTOR EIF-2B SUBUNIT BETA; 1.
DR   Pfam; PF01008; IF-2B; 1.
DR   SUPFAM; SSF100950; NagB/RpiA/CoA transferase-like; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000001300}.
SQ   SEQUENCE   356 AA;  38953 MW;  0CA4D919B009DBD8 CRC64;
     MSSQNRGDRE IDIFVEQFIS QLKRRQLSGS HAVALATAQL LLRFVSAARW NHIDSLVKDI
     RALGVRLVQT APKEIACRNI VSRVLTLIRE EQHGHKAENG GLSGSMLGLL EKNDKKEEVL
     DKAALRQANR DIRPYIIEGI QDLIDEVANI EENIAKMSVD EIHDNQIILT PTPASETVLL
     FLLKAARKRN FTVLVTEGFP NQIDAAHNMV EKLTKAGVEA IIIPDAAVYA VMSKVGRVIM
     GTSTVLANGG CLSSAGSALV CATATQHSTP VVVLTAIYKL SPVYPFDVPS MIEIGSSAQV
     ADYSDSEIVE GFQVFNPLAD YVPPEDIQIY NTNIGEFSPA FIYRIVLDHY SDAGNL
//