ID Q6C9S4_YARLI Unreviewed; 883 AA.
AC Q6C9S4;
DT 16-AUG-2004, integrated into UniProtKB/TrEMBL.
DT 16-AUG-2004, sequence version 1.
DT 27-MAR-2024, entry version 93.
DE SubName: Full=YALI0D08756p {ECO:0000313|EMBL:CAG80776.1};
GN ORFNames=YALI0_D08756g {ECO:0000313|EMBL:CAG80776.1};
OS Yarrowia lipolytica (strain CLIB 122 / E 150) (Yeast) (Candida lipolytica).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Dipodascaceae; Yarrowia.
OX NCBI_TaxID=284591 {ECO:0000313|EMBL:CAG80776.1, ECO:0000313|Proteomes:UP000001300};
RN [1] {ECO:0000313|EMBL:CAG80776.1, ECO:0000313|Proteomes:UP000001300}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CLIB 122 / E 150 {ECO:0000313|Proteomes:UP000001300};
RX PubMed=15229592; DOI=10.1038/nature02579;
RG Genolevures;
RA Dujon B., Sherman D., Fischer G., Durrens P., Casaregola S., Lafontaine I.,
RA de Montigny J., Marck C., Neuveglise C., Talla E., Goffard N., Frangeul L.,
RA Aigle M., Anthouard V., Babour A., Barbe V., Barnay S., Blanchin S.,
RA Beckerich J.M., Beyne E., Bleykasten C., Boisrame A., Boyer J.,
RA Cattolico L., Confanioleri F., de Daruvar A., Despons L., Fabre E.,
RA Fairhead C., Ferry-Dumazet H., Groppi A., Hantraye F., Hennequin C.,
RA Jauniaux N., Joyet P., Kachouri R., Kerrest A., Koszul R., Lemaire M.,
RA Lesur I., Ma L., Muller H., Nicaud J.M., Nikolski M., Oztas S.,
RA Ozier-Kalogeropoulos O., Pellenz S., Potier S., Richard G.F., Straub M.L.,
RA Suleau A., Swennene D., Tekaia F., Wesolowski-Louvel M., Westhof E.,
RA Wirth B., Zeniou-Meyer M., Zivanovic I., Bolotin-Fukuhara M., Thierry A.,
RA Bouchier C., Caudron B., Scarpelli C., Gaillardin C., Weissenbach J.,
RA Wincker P., Souciet J.L.;
RT "Genome evolution in yeasts.";
RL Nature 430:35-44(2004).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the XPC family. {ECO:0000256|ARBA:ARBA00009525}.
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DR EMBL; CR382130; CAG80776.1; -; Genomic_DNA.
DR RefSeq; XP_502588.1; XM_502588.1.
DR AlphaFoldDB; Q6C9S4; -.
DR STRING; 284591.Q6C9S4; -.
DR EnsemblFungi; CAG80776; CAG80776; YALI0_D08756g.
DR GeneID; 2910673; -.
DR KEGG; yli:YALI0D08756g; -.
DR VEuPathDB; FungiDB:YALI0_D08756g; -.
DR HOGENOM; CLU_003639_1_2_1; -.
DR InParanoid; Q6C9S4; -.
DR OMA; KPSKFEP; -.
DR OrthoDB; 181129at2759; -.
DR Proteomes; UP000001300; Chromosome D.
DR GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR GO; GO:0000111; C:nucleotide-excision repair factor 2 complex; IBA:GO_Central.
DR GO; GO:0071942; C:XPC complex; IBA:GO_Central.
DR GO; GO:0003684; F:damaged DNA binding; IBA:GO_Central.
DR GO; GO:0003697; F:single-stranded DNA binding; IBA:GO_Central.
DR GO; GO:0006298; P:mismatch repair; IBA:GO_Central.
DR GO; GO:0006289; P:nucleotide-excision repair; IBA:GO_Central.
DR Gene3D; 2.20.20.110; Rad4, beta-hairpin domain BHD1; 1.
DR Gene3D; 3.30.60.290; Rad4, beta-hairpin domain BHD2; 1.
DR Gene3D; 3.30.70.2460; Rad4, beta-hairpin domain BHD3; 1.
DR Gene3D; 3.90.260.10; Transglutaminase-like; 1.
DR InterPro; IPR018327; BHD_2.
DR InterPro; IPR004583; DNA_repair_Rad4.
DR InterPro; IPR038765; Papain-like_cys_pep_sf.
DR InterPro; IPR018325; Rad4/PNGase_transGLS-fold.
DR InterPro; IPR018326; Rad4_beta-hairpin_dom1.
DR InterPro; IPR018328; Rad4_beta-hairpin_dom3.
DR InterPro; IPR042488; Rad4_BHD3_sf.
DR InterPro; IPR036985; Transglutaminase-like_sf.
DR PANTHER; PTHR12135:SF3; DNA REPAIR PROTEIN RAD4; 1.
DR PANTHER; PTHR12135; DNA REPAIR PROTEIN XP-C / RAD4; 1.
DR Pfam; PF10403; BHD_1; 1.
DR Pfam; PF10404; BHD_2; 1.
DR Pfam; PF10405; BHD_3; 1.
DR Pfam; PF03835; Rad4; 1.
DR SMART; SM01030; BHD_1; 1.
DR SMART; SM01031; BHD_2; 1.
DR SMART; SM01032; BHD_3; 1.
DR SUPFAM; SSF54001; Cysteine proteinases; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW DNA damage {ECO:0000256|ARBA:ARBA00022763};
KW DNA repair {ECO:0000256|ARBA:ARBA00023204};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000001300}.
FT DOMAIN 463..519
FT /note="Rad4 beta-hairpin"
FT /evidence="ECO:0000259|SMART:SM01030"
FT DOMAIN 521..573
FT /note="Rad4 beta-hairpin"
FT /evidence="ECO:0000259|SMART:SM01031"
FT DOMAIN 580..655
FT /note="Rad4 beta-hairpin"
FT /evidence="ECO:0000259|SMART:SM01032"
FT REGION 26..145
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 309..340
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 772..883
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 700..727
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 45..70
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 71..86
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 87..101
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 318..340
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 813..850
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 883 AA; 99766 MW; 69F244B39C7B3B2E CRC64;
MGKRTVSQKD VTVTHFDMVR EYQVTEKKRK IEPSAPVAKL PSRAKQEKGN TSSRPASVER
ASSQTTTFDL DADESSDEED WEEVDIDPSA SSTNAETGIS VSFEPGASIA EESVIRGGWD
TKGTNVTSKK GKGKRTGPKL SREERQRRIQ VHQIHIMALL KHASIRNAWA NDLLLQMQLR
ETVPATKLTG LTPDKTQTKM VRTAKFYESL KYLLQQWAKI WYTDSRGLHK RDFNELDDIN
PDSYDPPVTK AIFNKKVIRH RGSRDLKVQG FVALLRAVGV QARLVVSLQP LDFASNTIVS
DLAAEKQPAE KASPSVLRKP KFSSTSGQSK SAQRSQSRMH YSESPTPVYW VEVFEPTGQK
WVSLDPACEV NMEVVGKAGK SRIEPSLQDK LNTLTYALAF NKEGTVTDVT RRYSSAYNSR
TRPARLTRYL AGSIWWNKLM GLYRPPITHA SWAEEKFLRE RVLAEGFPKN IQLFKNHPRY
VLERHLRQDE VLKEKNPCGI MSMKTNSKPE NVYPRSDVQQ VKSANKWYQI GRIIKPGQIC
KKRKKMAKSR FRLDEEEDSP MYSFDQTEAY IPQPVVDGQV PRNGYGNVDL FTPFMMPPGG
AHVRGKGAYM AAKSLGIDYA NCVVGFDFTK GRQIKPRIDG VIVAEKYAKD VADVWSDMQE
QTLAKEERNR EVRALLRWRR YLTALKIRHR LDAEHGEVEL ESGEEEEEDE EVRVEEVNEE
VKEKEENGVI IIDDNESDEP WYVPPSVLQP KLDQYLNKSA FRLDKPLNIV VDEPEEEKEE
EIPREASTLA STPSSTPCLT PPPRDSTTPR ENGADKTRPS QLQRASSVVS VGSTDTISSE
EGNPLSELSS VIKSPVKIDY SSLAVADDSD SPDEMSESEL YSE
//
