ID Q6CC41_YARLI Unreviewed; 1470 AA.
AC Q6CC41;
DT 16-AUG-2004, integrated into UniProtKB/TrEMBL.
DT 16-AUG-2004, sequence version 1.
DT 27-MAR-2024, entry version 110.
DE SubName: Full=YALI0C12661p {ECO:0000313|EMBL:CAG82081.1};
GN ORFNames=YALI0_C12661g {ECO:0000313|EMBL:CAG82081.1};
OS Yarrowia lipolytica (strain CLIB 122 / E 150) (Yeast) (Candida lipolytica).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Dipodascaceae; Yarrowia.
OX NCBI_TaxID=284591 {ECO:0000313|EMBL:CAG82081.1, ECO:0000313|Proteomes:UP000001300};
RN [1] {ECO:0000313|EMBL:CAG82081.1, ECO:0000313|Proteomes:UP000001300}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CLIB 122 / E 150 {ECO:0000313|Proteomes:UP000001300};
RX PubMed=15229592; DOI=10.1038/nature02579;
RG Genolevures;
RA Dujon B., Sherman D., Fischer G., Durrens P., Casaregola S., Lafontaine I.,
RA de Montigny J., Marck C., Neuveglise C., Talla E., Goffard N., Frangeul L.,
RA Aigle M., Anthouard V., Babour A., Barbe V., Barnay S., Blanchin S.,
RA Beckerich J.M., Beyne E., Bleykasten C., Boisrame A., Boyer J.,
RA Cattolico L., Confanioleri F., de Daruvar A., Despons L., Fabre E.,
RA Fairhead C., Ferry-Dumazet H., Groppi A., Hantraye F., Hennequin C.,
RA Jauniaux N., Joyet P., Kachouri R., Kerrest A., Koszul R., Lemaire M.,
RA Lesur I., Ma L., Muller H., Nicaud J.M., Nikolski M., Oztas S.,
RA Ozier-Kalogeropoulos O., Pellenz S., Potier S., Richard G.F., Straub M.L.,
RA Suleau A., Swennene D., Tekaia F., Wesolowski-Louvel M., Westhof E.,
RA Wirth B., Zeniou-Meyer M., Zivanovic I., Bolotin-Fukuhara M., Thierry A.,
RA Bouchier C., Caudron B., Scarpelli C., Gaillardin C., Weissenbach J.,
RA Wincker P., Souciet J.L.;
RT "Genome evolution in yeasts.";
RL Nature 430:35-44(2004).
CC -!- SUBCELLULAR LOCATION: Endoplasmic reticulum lumen
CC {ECO:0000256|ARBA:ARBA00004319}.
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DR EMBL; CR382129; CAG82081.1; -; Genomic_DNA.
DR RefSeq; XP_501771.1; XM_501771.1.
DR SMR; Q6CC41; -.
DR STRING; 284591.Q6CC41; -.
DR CAZy; GT24; Glycosyltransferase Family 24.
DR EnsemblFungi; CAG82081; CAG82081; YALI0_C12661g.
DR GeneID; 2909509; -.
DR KEGG; yli:YALI0C12661g; -.
DR VEuPathDB; FungiDB:YALI0_C12661g; -.
DR HOGENOM; CLU_002668_1_0_1; -.
DR InParanoid; Q6CC41; -.
DR OMA; VYETEHE; -.
DR OrthoDB; 1734at2759; -.
DR UniPathway; UPA00378; -.
DR Proteomes; UP000001300; Chromosome C.
DR GO; GO:0005783; C:endoplasmic reticulum; IBA:GO_Central.
DR GO; GO:0005788; C:endoplasmic reticulum lumen; IEA:UniProtKB-SubCell.
DR GO; GO:0003980; F:UDP-glucose:glycoprotein glucosyltransferase activity; IBA:GO_Central.
DR GO; GO:0051082; F:unfolded protein binding; IBA:GO_Central.
DR GO; GO:0071712; P:ER-associated misfolded protein catabolic process; IBA:GO_Central.
DR GO; GO:0018279; P:protein N-linked glycosylation via asparagine; IBA:GO_Central.
DR CDD; cd06432; GT8_HUGT1_C_like; 1.
DR InterPro; IPR040497; Glyco_transf_24.
DR InterPro; IPR029044; Nucleotide-diphossugar_trans.
DR InterPro; IPR009448; UDP-g_GGtrans.
DR InterPro; IPR040693; UGGT_TRXL_1.
DR InterPro; IPR040694; UGGT_TRXL_2.
DR InterPro; IPR040692; UGGT_TRXL_3.
DR PANTHER; PTHR11226; UDP-GLUCOSE GLYCOPROTEIN:GLUCOSYLTRANSFERASE; 1.
DR PANTHER; PTHR11226:SF0; UDP-GLUCOSE:GLYCOPROTEIN GLUCOSYLTRANSFERASE; 1.
DR Pfam; PF18404; Glyco_transf_24; 1.
DR Pfam; PF18400; Thioredoxin_12; 1.
DR Pfam; PF18401; Thioredoxin_13; 1.
DR Pfam; PF18402; Thioredoxin_14; 1.
DR Pfam; PF06427; UDP-g_GGTase; 1.
DR SUPFAM; SSF53448; Nucleotide-diphospho-sugar transferases; 1.
PE 4: Predicted;
KW Endoplasmic reticulum {ECO:0000256|ARBA:ARBA00022824};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Reference proteome {ECO:0000313|Proteomes:UP000001300};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..18
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 19..1470
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5004271526"
FT DOMAIN 32..210
FT /note="UGGT thioredoxin-like"
FT /evidence="ECO:0000259|Pfam:PF18400"
FT DOMAIN 249..377
FT /note="UGGT thioredoxin-like"
FT /evidence="ECO:0000259|Pfam:PF18401"
FT DOMAIN 385..611
FT /note="UGGT thioredoxin-like"
FT /evidence="ECO:0000259|Pfam:PF18402"
FT DOMAIN 1164..1432
FT /note="Glucosyltransferase 24 catalytic"
FT /evidence="ECO:0000259|Pfam:PF18404"
FT REGION 612..631
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1434..1470
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1434..1451
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1452..1470
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1470 AA; 165685 MW; A7B604B70D090617 CRC64;
MKLLKYAAAA LFASSVAANV TVELKAQWQS DFLLELVETL STEHTYFDFI NHIAEQVEDG
ANYTDKEWYD NLTAFAASKS EISDFQKSLT DAALAFRRES PLIETFYQLG DSQESECDIF
FTYNGKKYCD SNDLFTLKTT KMPKNPSVYF FDHVARSVQA NKHLKNIPVT VLYADLRSPE
FPLFHKILYQ EAQDGKMVYI LRYRRSDRSE RVTMTGYGAE LSLKKTDYLV LDDDANTEKL
TDNKNPVYTK RELQNMGLNA AQFVLNHRKD PEAALKALKE VSFDFPLLSS SLNNTKPVKG
FQKALQENTA AGDFMPGANQ MFVNGALLST SASNLQSLFD LVALEHSRLE VLAKTLKGAI
SAEQLASILN DYPLQHALES QPQRIDYRDA DALLWLNNLA TDIQYQEWPR SVASLLQNQI
NLAHNAQTVV MPFNMDDFAD VKVDKETGEL INMHPINRGK LTVLFTMLQR SMPIQFGVVP
YGSTLKGKKL SQYLHYLARN VDATASLRFL FALGAGTPVE EIFTQIPAEI TQESVDEALK
EESYEPYVTA SREWMKKLGM NEAQTQEPAF VMNGIVMPFS EKWQNLVGAR FQQDLPEMLK
LVQKQIIKVS KEAPVGEDDE DEDDENAGNP VDKYFANHEI KDLLVEGSPT RRNLILSPAS
FTNLQYLESD LNLKDVSTAT IAGTTASIFS NSILAGNFAS TQFVSQLLAL IEAQQEEKDR
FAFRTQFVHI GQTDSAKGQV INGVVQKLTE LAGEEQVSLL KDALAYLEGD NASFSAKKVP
FDKTITASEE VKYLKQFKTT ESSTLLIIDG LVNDISSKAM LLDKSEVIAL YEREAVRRLE
LTSVALSDLK LLTKSVENNL DLAKVHIPLA KIFYGDATEQ ESTLYDVRAF HHIRWNKDVS
SFVLGDESTS LVKIVAAVDV LSDGGQRLVS QIEAISKVTG VSVRVFPSPK APDARQEPTL
PLKRFYRAHN SVVPEFDAEG AHKVPNLNFE GLPAQNLLTF GLDAPSSWIA MPADNTHDLD
NILLEEDSED FVDASYSLQN ILIEGSIIDI TKNSYAPGTD LLLKSTLTGE SSDTLVMSNL
GYFQLQAGPG LWELNLGPSA SDVYETEHEV IIPVTDVLGP HISLSMERKK GKENVVVGAS
QDKAKLWSKL KKSTGVSTKK QADINIFTVA SGHLYERFLS IMTASVMAHT DHTVKFWLIE
NFLSASFKAF LPHLAAHYGF EYELVTYQWP HWLRGQTEKQ RQIWGYKILF LDVLFPQDLE
RVIFIDSDQI VRTDLYELVE MDLEGAPYGF TPMCDSRKEM DGFRFWKQGY WDTFLGDDLV
YHISALFVVD LKVFRAQQIG DRLRVHYHQL SADPASLSNL DQDLPNNLQR QVPIFSLPQD
WLWCETWCSD ESLKTAKTID MCNNPLTKEP KLDRARRQVP EWTKYDDEIR KLRKEAEGIE
GKKKEEEERA GPVEVEVEID EPEADLHDEL
//
