ID Q6CG19_YARLI Unreviewed; 967 AA.
AC Q6CG19;
DT 16-AUG-2004, integrated into UniProtKB/TrEMBL.
DT 16-AUG-2004, sequence version 1.
DT 27-MAR-2024, entry version 108.
DE SubName: Full=YALI0B01628p {ECO:0000313|EMBL:CAG82610.1};
GN ORFNames=YALI0_B01628g {ECO:0000313|EMBL:CAG82610.1};
OS Yarrowia lipolytica (strain CLIB 122 / E 150) (Yeast) (Candida lipolytica).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Dipodascaceae; Yarrowia.
OX NCBI_TaxID=284591 {ECO:0000313|EMBL:CAG82610.1, ECO:0000313|Proteomes:UP000001300};
RN [1] {ECO:0000313|EMBL:CAG82610.1, ECO:0000313|Proteomes:UP000001300}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CLIB 122 / E 150 {ECO:0000313|Proteomes:UP000001300};
RX PubMed=15229592; DOI=10.1038/nature02579;
RG Genolevures;
RA Dujon B., Sherman D., Fischer G., Durrens P., Casaregola S., Lafontaine I.,
RA de Montigny J., Marck C., Neuveglise C., Talla E., Goffard N., Frangeul L.,
RA Aigle M., Anthouard V., Babour A., Barbe V., Barnay S., Blanchin S.,
RA Beckerich J.M., Beyne E., Bleykasten C., Boisrame A., Boyer J.,
RA Cattolico L., Confanioleri F., de Daruvar A., Despons L., Fabre E.,
RA Fairhead C., Ferry-Dumazet H., Groppi A., Hantraye F., Hennequin C.,
RA Jauniaux N., Joyet P., Kachouri R., Kerrest A., Koszul R., Lemaire M.,
RA Lesur I., Ma L., Muller H., Nicaud J.M., Nikolski M., Oztas S.,
RA Ozier-Kalogeropoulos O., Pellenz S., Potier S., Richard G.F., Straub M.L.,
RA Suleau A., Swennene D., Tekaia F., Wesolowski-Louvel M., Westhof E.,
RA Wirth B., Zeniou-Meyer M., Zivanovic I., Bolotin-Fukuhara M., Thierry A.,
RA Bouchier C., Caudron B., Scarpelli C., Gaillardin C., Weissenbach J.,
RA Wincker P., Souciet J.L.;
RT "Genome evolution in yeasts.";
RL Nature 430:35-44(2004).
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DR EMBL; CR382128; CAG82610.1; -; Genomic_DNA.
DR RefSeq; XP_500393.1; XM_500393.1.
DR AlphaFoldDB; Q6CG19; -.
DR STRING; 284591.Q6CG19; -.
DR EnsemblFungi; CAG82610; CAG82610; YALI0_B01628g.
DR GeneID; 2906898; -.
DR KEGG; yli:YALI0B01628g; -.
DR VEuPathDB; FungiDB:YALI0_B01628g; -.
DR HOGENOM; CLU_003538_0_1_1; -.
DR InParanoid; Q6CG19; -.
DR OrthoDB; 3034081at2759; -.
DR Proteomes; UP000001300; Chromosome B.
DR GO; GO:0005737; C:cytoplasm; IEA:EnsemblFungi.
DR GO; GO:0005096; F:GTPase activator activity; IBA:GO_Central.
DR Gene3D; 1.10.238.10; EF-hand; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR Gene3D; 1.10.8.270; putative rabgap domain of human tbc1 domain family member 14 like domains; 1.
DR Gene3D; 1.10.472.80; Ypt/Rab-GAP domain of gyp1p, domain 3; 1.
DR InterPro; IPR011992; EF-hand-dom_pair.
DR InterPro; IPR004182; GRAM.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR000195; Rab-GAP-TBC_dom.
DR InterPro; IPR035969; Rab-GAP_TBC_sf.
DR PANTHER; PTHR47219:SF20; GTPASE ACTIVATING PROTEIN GYP2; 1.
DR PANTHER; PTHR47219; RAB GTPASE-ACTIVATING PROTEIN 1-LIKE; 1.
DR Pfam; PF02893; GRAM; 1.
DR Pfam; PF00566; RabGAP-TBC; 1.
DR SMART; SM00568; GRAM; 1.
DR SMART; SM00164; TBC; 1.
DR SUPFAM; SSF47473; EF-hand; 1.
DR SUPFAM; SSF47923; Ypt/Rab-GAP domain of gyp1p; 2.
DR PROSITE; PS50086; TBC_RABGAP; 1.
PE 4: Predicted;
KW GTPase activation {ECO:0000256|ARBA:ARBA00022468};
KW Reference proteome {ECO:0000313|Proteomes:UP000001300}.
FT DOMAIN 262..450
FT /note="Rab-GAP TBC"
FT /evidence="ECO:0000259|PROSITE:PS50086"
FT REGION 735..765
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 841..861
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 967 AA; 109445 MW; 2E2884F98339BB72 CRC64;
MSFLTSLKNK ALELFEPETS SGVIQTAADT AQFSDYKRRL NKDEKFRLQF SLPDSQKLLA
DISVEVALQN AENPPVNPGQ AARSESLIEF SNVIYQGKLY LSDSFLCFTA TDARQCSFAL
PLLTVKRVER LPLKSYLFAL SIKTYNGLTL VIQFIGIKSA CDRFSLALKA QLGKNLAKIK
SLKPFLATLY SEYLLNVISS GQKGDAPPPP LGGLGQVFRY PGDAKKLRDK SKMRLWLEYF
QTHGRNLTLV RQQTFYKLIR VGLPNRLRGE IWELTSGSLY LRLAHQSMYN DLLEEYEGKT
SQATEEIEKD LNRSLPEYSA YQDEEGIARL RRVLTVYSWK NPDVGYCQAM NIVIAAFLIY
MSEEQAFWCL NVLCDKMLPG YYSKSMYGTL LDQKVFESLV EKTMPLLWDH LQRCDVQLSV
VSLPWFLSIF INSMPLVFAF RIIDVFFLEG PKLLFQVALA ILRINGERLL EADDDGLMIG
IIKEYFLTLD QSAHPTSKNE KLRSITKFQE LMVVAMKEFS VITEPLITEQ RAKYQDRVLE
DIEIFAKRTS IRNLHKTKNL SQDDLSVLYD RYHTYREMNL ENYQNFLSSV VCWTEPQELS
IDGTPDFLRR LYTRWDADMK GTLSLQNVVT GIDALKQSDL MGLMTYFFEL YDDDGDGQID
REGILSMSEG LLFLTKAWRE GTVYTDGAPI LDQISLVELD RREQERQELL QQEEIRLAEE
MEALRLEAEQ QKLAEENTSE AIFDTPDTDE DDAKSTKSSK SAKSVSSRSI KSTIGSIGAA
GGAVSGAAIG AVRGAVRRKS FKDIGDPMQE RQKVAHEQNV RYLSAVSAFI QRAFEYANEA
KKEADKEAAG DKGKDSEDSV EAHNAALDPS KPLFIDLPTF RMVVLADETL ETLFAVSLPQ
SVILRQSDAD RHKRASLRDV FDGLVADGMR VAGEVRKRID IDKSVNDSED IGEVVSGKDR
DVLDEAI
//
