ID Q6CI31_YARLI Unreviewed; 755 AA.
AC Q6CI31;
DT 16-AUG-2004, integrated into UniProtKB/TrEMBL.
DT 16-AUG-2004, sequence version 1.
DT 27-MAR-2024, entry version 101.
DE SubName: Full=YALI0A02200p {ECO:0000313|EMBL:CAG83603.1};
GN ORFNames=YALI0_A02200g {ECO:0000313|EMBL:CAG83603.1};
OS Yarrowia lipolytica (strain CLIB 122 / E 150) (Yeast) (Candida lipolytica).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Dipodascaceae; Yarrowia.
OX NCBI_TaxID=284591 {ECO:0000313|EMBL:CAG83603.1, ECO:0000313|Proteomes:UP000001300};
RN [1] {ECO:0000313|EMBL:CAG83603.1, ECO:0000313|Proteomes:UP000001300}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CLIB 122 / E 150 {ECO:0000313|Proteomes:UP000001300};
RX PubMed=15229592; DOI=10.1038/nature02579;
RG Genolevures;
RA Dujon B., Sherman D., Fischer G., Durrens P., Casaregola S., Lafontaine I.,
RA de Montigny J., Marck C., Neuveglise C., Talla E., Goffard N., Frangeul L.,
RA Aigle M., Anthouard V., Babour A., Barbe V., Barnay S., Blanchin S.,
RA Beckerich J.M., Beyne E., Bleykasten C., Boisrame A., Boyer J.,
RA Cattolico L., Confanioleri F., de Daruvar A., Despons L., Fabre E.,
RA Fairhead C., Ferry-Dumazet H., Groppi A., Hantraye F., Hennequin C.,
RA Jauniaux N., Joyet P., Kachouri R., Kerrest A., Koszul R., Lemaire M.,
RA Lesur I., Ma L., Muller H., Nicaud J.M., Nikolski M., Oztas S.,
RA Ozier-Kalogeropoulos O., Pellenz S., Potier S., Richard G.F., Straub M.L.,
RA Suleau A., Swennene D., Tekaia F., Wesolowski-Louvel M., Westhof E.,
RA Wirth B., Zeniou-Meyer M., Zivanovic I., Bolotin-Fukuhara M., Thierry A.,
RA Bouchier C., Caudron B., Scarpelli C., Gaillardin C., Weissenbach J.,
RA Wincker P., Souciet J.L.;
RT "Genome evolution in yeasts.";
RL Nature 430:35-44(2004).
CC -!- PATHWAY: Protein modification; protein ubiquitination.
CC {ECO:0000256|ARBA:ARBA00004906}.
CC -!- SIMILARITY: Belongs to the cullin family.
CC {ECO:0000256|ARBA:ARBA00006019, ECO:0000256|PROSITE-ProRule:PRU00330,
CC ECO:0000256|RuleBase:RU003829}.
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DR EMBL; CR382127; CAG83603.1; -; Genomic_DNA.
DR RefSeq; XP_499680.1; XM_499680.1.
DR AlphaFoldDB; Q6CI31; -.
DR STRING; 284591.Q6CI31; -.
DR EnsemblFungi; CAG83603; CAG83603; YALI0_A02200g.
DR GeneID; 2906137; -.
DR KEGG; yli:YALI0A02200g; -.
DR VEuPathDB; FungiDB:YALI0_A02200g; -.
DR HOGENOM; CLU_004747_7_0_1; -.
DR InParanoid; Q6CI31; -.
DR OrthoDB; 5474206at2759; -.
DR Proteomes; UP000001300; Chromosome A.
DR GO; GO:0080008; C:Cul4-RING E3 ubiquitin ligase complex; IBA:GO_Central.
DR GO; GO:0031625; F:ubiquitin protein ligase binding; IBA:GO_Central.
DR GO; GO:0006974; P:DNA damage response; IBA:GO_Central.
DR GO; GO:0016567; P:protein ubiquitination; IBA:GO_Central.
DR GO; GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
DR Gene3D; 1.20.1310.10; Cullin Repeats; 2.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR045093; Cullin.
DR InterPro; IPR016158; Cullin_homology.
DR InterPro; IPR036317; Cullin_homology_sf.
DR InterPro; IPR001373; Cullin_N.
DR InterPro; IPR019559; Cullin_neddylation_domain.
DR InterPro; IPR016159; Cullin_repeat-like_dom_sf.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR11932; CULLIN; 1.
DR PANTHER; PTHR11932:SF168; CULLIN-3; 1.
DR Pfam; PF00888; Cullin; 1.
DR Pfam; PF10557; Cullin_Nedd8; 1.
DR SMART; SM00182; CULLIN; 1.
DR SMART; SM00884; Cullin_Nedd8; 1.
DR SUPFAM; SSF75632; Cullin homology domain; 1.
DR SUPFAM; SSF74788; Cullin repeat-like; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS50069; CULLIN_2; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000001300}.
FT DOMAIN 396..631
FT /note="Cullin family profile"
FT /evidence="ECO:0000259|PROSITE:PS50069"
SQ SEQUENCE 755 AA; 86702 MW; D9AA6480C841F86E CRC64;
MKFGGQSLVL TSMKRGIERH VGKFYTRKIA AKNIKVERRQ SSNDGEAIQR FFEQQQQVLL
AQTKIIALDG GAVTVPEEEL YRMVETFCRH GKGAQCWQSL FKECIEPLTT KCLENIEAIS
QAGLKSITAA FLDEYDMWRS RILKLQLIYF YLDRSFLLQS GNGGSDILRR CQDLVRDRIY
AVISQRVETD FASIFANLVR GASDSALLLQ QCENVVRELC GESSEQYQRI IKTVAVQSRL
YFKLQAEKWQ IMSPVQYLQL VVDTQVTEHR RIQELIKDSS RVEMIMSALP EEMIVPHVQF
IRRGVTESFE DELMFPYIRQ LSLLSFEGSE QQLRIGDIFR QWIETVLGPT FTNIDIVVQS
YHKSSRVTEA LADADLINKA PDWVAGFRNS MRGKRNLSEQ LAKFSDSLLR KGAKGGDSLK
NTADVKTLTF LLSCIPEKDV FEVYYKRYLS KRLLVGRALG LESESELLTI LRDEFGPELT
ESMETMLKDV RTNSPATMAQ YRDSEIYTKY GNFDLNVNML SQNAWPQFPA STSPIRLPSQ
MYSQLDNFSK FLSQDPKNTK KKVTWQHALS SCTIRAHLNE DTKEFDVSLH QALVMMQFVD
EKKRPHMTFA DLLAATGISE RELTMSLHSL MTPKVKILIK EEGDETRYKF NWNFSSKLRR
VKVPSVARGA DDIMLPHKAI QDTLERDRNM EIQAVIIRIM KARRTVGHAE LVMEVLDKTK
SRGILEVADV KKNISKLITD DFISRQGRDV YDYVA
//
