ID Q6CID7_KLULA Unreviewed; 844 AA.
AC Q6CID7;
DT 16-AUG-2004, integrated into UniProtKB/TrEMBL.
DT 16-AUG-2004, sequence version 1.
DT 27-MAR-2024, entry version 89.
DE SubName: Full=KLLA0F27467p {ECO:0000313|EMBL:CAG99010.1};
GN ORFNames=KLLA0_F27467g {ECO:0000313|EMBL:CAG99010.1};
OS Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 /
OS NRRL Y-1140 / WM37) (Yeast) (Candida sphaerica).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Saccharomycetaceae; Kluyveromyces.
OX NCBI_TaxID=284590 {ECO:0000313|EMBL:CAG99010.1, ECO:0000313|Proteomes:UP000000598};
RN [1] {ECO:0000313|EMBL:CAG99010.1, ECO:0000313|Proteomes:UP000000598}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 /
RC WM37 {ECO:0000313|Proteomes:UP000000598};
RX PubMed=15229592; DOI=10.1038/nature02579;
RG Genolevures;
RA Dujon B., Sherman D., Fischer G., Durrens P., Casaregola S., Lafontaine I.,
RA de Montigny J., Marck C., Neuveglise C., Talla E., Goffard N., Frangeul L.,
RA Aigle M., Anthouard V., Babour A., Barbe V., Barnay S., Blanchin S.,
RA Beckerich J.M., Beyne E., Bleykasten C., Boisrame A., Boyer J.,
RA Cattolico L., Confanioleri F., de Daruvar A., Despons L., Fabre E.,
RA Fairhead C., Ferry-Dumazet H., Groppi A., Hantraye F., Hennequin C.,
RA Jauniaux N., Joyet P., Kachouri R., Kerrest A., Koszul R., Lemaire M.,
RA Lesur I., Ma L., Muller H., Nicaud J.M., Nikolski M., Oztas S.,
RA Ozier-Kalogeropoulos O., Pellenz S., Potier S., Richard G.F., Straub M.L.,
RA Suleau A., Swennene D., Tekaia F., Wesolowski-Louvel M., Westhof E.,
RA Wirth B., Zeniou-Meyer M., Zivanovic I., Bolotin-Fukuhara M., Thierry A.,
RA Bouchier C., Caudron B., Scarpelli C., Gaillardin C., Weissenbach J.,
RA Wincker P., Souciet J.L.;
RT "Genome evolution in yeasts.";
RL Nature 430:35-44(2004).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the SYG1 (TC 2.A.94) family.
CC {ECO:0000256|ARBA:ARBA00009665}.
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DR EMBL; CR382126; CAG99010.1; -; Genomic_DNA.
DR RefSeq; XP_456302.1; XM_456302.1.
DR AlphaFoldDB; Q6CID7; -.
DR STRING; 284590.Q6CID7; -.
DR PaxDb; 284590-Q6CID7; -.
DR GeneID; 2894809; -.
DR KEGG; kla:KLLA0_F27467g; -.
DR eggNOG; KOG1162; Eukaryota.
DR HOGENOM; CLU_006116_1_1_1; -.
DR InParanoid; Q6CID7; -.
DR OMA; IGVMFAH; -.
DR Proteomes; UP000000598; Chromosome F.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR CDD; cd14475; SPX_SYG1_like; 1.
DR InterPro; IPR004342; EXS_C.
DR InterPro; IPR004331; SPX_dom.
DR PANTHER; PTHR10783:SF103; XENOTROPIC AND POLYTROPIC RETROVIRUS RECEPTOR 1; 1.
DR PANTHER; PTHR10783; XENOTROPIC AND POLYTROPIC RETROVIRUS RECEPTOR 1-RELATED; 1.
DR Pfam; PF03124; EXS; 1.
DR Pfam; PF03105; SPX; 2.
DR PROSITE; PS51380; EXS; 1.
DR PROSITE; PS51382; SPX; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000000598};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 345..365
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 385..403
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 439..459
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 465..487
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 499..515
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 585..607
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 619..638
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 677..696
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 1..243
FT /note="SPX"
FT /evidence="ECO:0000259|PROSITE:PS51382"
FT DOMAIN 551..761
FT /note="EXS"
FT /evidence="ECO:0000259|PROSITE:PS51380"
SQ SEQUENCE 844 AA; 99996 MW; 7E973CE51E6B99BD CRC64;
MKFAEHLRES VVPEWSDKYV NYKLGKKKIK QFQKLKKVQD VGSMDRTIVR EFIDDWLVRD
QLKNCDEFYE WQLSKYRAKY HKLQRQIHLY VLEADKRSRL DSLDEYRIAS LSRAPDSYGS
IFPNFSPIAL KDTVKKKIWY DLKRWLVTHN LCPSMPVSWK NRDPLLAKKD RKRASRGQET
FQTETSPLSL SQIRQQLSDA ILDFYLYLQL LKNYRDLNVN GFRKIVKKFD KVLHQDQLKT
FMPYAKKYSI MFSQYDEYLK LIKDNVEHAE VINVNLFLGS DNDVDRLKKD PLTFWEQTAI
KWYTMTLTSS SKDKKHNLER IKNLSLQYSV NEQTIHRNNA SMFQMFLGSA QLGISVTLVI
LMTIILAKNS SDEVRSALLP IWSSFHYLTF MGLLFIIDCF IWYKVKINYR FIMFGEIHSR
NGPVLFNNDF GMTHIPLQFF HATTFLCICS ILAFCSLMLE KLEPWMITWL CIAVALFFWK
FQVIQPWPYW YETFQSRKYI FTSFIRLVFS GFFPVQFGDF FLGDIVCSLT YSMSQFATLG
CLTFNDSKED KCRYEKLMWI GILSCLPSYW RFVQCVRRYF DSYDWFPHLL NAFKYLLGIS
FNASLYWYKS WPQMQKFKVL LIVFGCLNST LTSIWDLIMD WSLLQTKSKN FLLRDDLYLC
GKKNWKSGKY SSKKKCIYYF IMVFDVVVRY EWVFYMVKNN TDYVRHPLIA LAMATLEILR
RFVWVILRVE NEHVANVHLF KVTDDNWQLP FPTIEDSELH MEEDYSAAAE NMDNIAMLSV
MKSDLESQQQ RPRSTSAVPK LNRKASVFEI IPWAHATDFQ RPIETASVNS AAISDSESEA
ESEV
//
