ID Q6CJW6_KLULA Unreviewed; 386 AA.
AC Q6CJW6;
DT 16-AUG-2004, integrated into UniProtKB/TrEMBL.
DT 16-AUG-2004, sequence version 1.
DT 24-JAN-2024, entry version 93.
DE RecName: Full=Protein HGH1 homolog {ECO:0000256|ARBA:ARBA00014076};
GN ORFNames=KLLA0_F15433g {ECO:0000313|EMBL:CAG98481.1};
OS Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 /
OS NRRL Y-1140 / WM37) (Yeast) (Candida sphaerica).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Saccharomycetaceae; Kluyveromyces.
OX NCBI_TaxID=284590 {ECO:0000313|EMBL:CAG98481.1, ECO:0000313|Proteomes:UP000000598};
RN [1] {ECO:0000313|EMBL:CAG98481.1, ECO:0000313|Proteomes:UP000000598}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 /
RC WM37 {ECO:0000313|Proteomes:UP000000598};
RX PubMed=15229592; DOI=10.1038/nature02579;
RG Genolevures;
RA Dujon B., Sherman D., Fischer G., Durrens P., Casaregola S., Lafontaine I.,
RA de Montigny J., Marck C., Neuveglise C., Talla E., Goffard N., Frangeul L.,
RA Aigle M., Anthouard V., Babour A., Barbe V., Barnay S., Blanchin S.,
RA Beckerich J.M., Beyne E., Bleykasten C., Boisrame A., Boyer J.,
RA Cattolico L., Confanioleri F., de Daruvar A., Despons L., Fabre E.,
RA Fairhead C., Ferry-Dumazet H., Groppi A., Hantraye F., Hennequin C.,
RA Jauniaux N., Joyet P., Kachouri R., Kerrest A., Koszul R., Lemaire M.,
RA Lesur I., Ma L., Muller H., Nicaud J.M., Nikolski M., Oztas S.,
RA Ozier-Kalogeropoulos O., Pellenz S., Potier S., Richard G.F., Straub M.L.,
RA Suleau A., Swennene D., Tekaia F., Wesolowski-Louvel M., Westhof E.,
RA Wirth B., Zeniou-Meyer M., Zivanovic I., Bolotin-Fukuhara M., Thierry A.,
RA Bouchier C., Caudron B., Scarpelli C., Gaillardin C., Weissenbach J.,
RA Wincker P., Souciet J.L.;
RT "Genome evolution in yeasts.";
RL Nature 430:35-44(2004).
CC -!- SIMILARITY: Belongs to the HGH1 family.
CC {ECO:0000256|ARBA:ARBA00006712}.
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DR EMBL; CR382126; CAG98481.1; -; Genomic_DNA.
DR RefSeq; XP_455773.1; XM_455773.1.
DR AlphaFoldDB; Q6CJW6; -.
DR STRING; 284590.Q6CJW6; -.
DR PaxDb; 284590-Q6CJW6; -.
DR GeneID; 2895999; -.
DR KEGG; kla:KLLA0_F15433g; -.
DR eggNOG; KOG2973; Eukaryota.
DR HOGENOM; CLU_037769_2_1_1; -.
DR InParanoid; Q6CJW6; -.
DR OMA; MCILLTN; -.
DR Proteomes; UP000000598; Chromosome F.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR039717; Hgh1.
DR InterPro; IPR007206; Protein_HGH1_C.
DR InterPro; IPR007205; Protein_HGH1_N.
DR PANTHER; PTHR13387; PROTEIN HGH1 HOMOLOG; 1.
DR PANTHER; PTHR13387:SF9; PROTEIN HGH1 HOMOLOG; 1.
DR Pfam; PF04063; DUF383; 1.
DR Pfam; PF04064; DUF384; 1.
DR SUPFAM; SSF48371; ARM repeat; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000000598}.
FT DOMAIN 95..289
FT /note="Protein HGH1 N-terminal"
FT /evidence="ECO:0000259|Pfam:PF04063"
FT DOMAIN 294..347
FT /note="Protein HGH1 C-terminal"
FT /evidence="ECO:0000259|Pfam:PF04064"
FT REGION 359..386
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 362..386
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 386 AA; 44117 MW; 7C2D21B317A54F7C CRC64;
MSTELEELVS FLHSDQPAVR QIALDNLVGF STGASAVIFK CNNYKAIEDL KVLAKDKSKV
IVQQSTTILA NLCDDVTMRK LIVKDTEFLQ YLSWKICDLA NASADIMCIL LSNLAKEDNI
TELFSFVKKE DDGIPLNIEV FKSNKVMDCL MDCFVKGYDR KLNRYATYDY LAYFFADISR
FKIGREYFIE QQEYDGVIPI SKLLVFTEKY DAKTRREGVA YTIKNSLFDS EKHENLLTNE
EINLLPYILL PIASAKDSEI DEEDMFNLPD ELQLLPADKE RDPIPEIICV HLESILLLCT
TKAGREYLRS KSVYPLVREL HKNIGNDDIG ELSHRIVNML MRGEPENQVI EEIVAKSAED
GEIAEIEEEE EEEESDDDDD AIVEVL
//
