ID Q6CK04_KLULA Unreviewed; 851 AA.
AC Q6CK04;
DT 16-AUG-2004, integrated into UniProtKB/TrEMBL.
DT 16-AUG-2004, sequence version 1.
DT 27-MAR-2024, entry version 98.
DE SubName: Full=KLLA0F14575p {ECO:0000313|EMBL:CAG98443.1};
GN ORFNames=KLLA0_F14575g {ECO:0000313|EMBL:CAG98443.1};
OS Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 /
OS NRRL Y-1140 / WM37) (Yeast) (Candida sphaerica).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Saccharomycetaceae; Kluyveromyces.
OX NCBI_TaxID=284590 {ECO:0000313|EMBL:CAG98443.1, ECO:0000313|Proteomes:UP000000598};
RN [1] {ECO:0000313|EMBL:CAG98443.1, ECO:0000313|Proteomes:UP000000598}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 /
RC WM37 {ECO:0000313|Proteomes:UP000000598};
RX PubMed=15229592; DOI=10.1038/nature02579;
RG Genolevures;
RA Dujon B., Sherman D., Fischer G., Durrens P., Casaregola S., Lafontaine I.,
RA de Montigny J., Marck C., Neuveglise C., Talla E., Goffard N., Frangeul L.,
RA Aigle M., Anthouard V., Babour A., Barbe V., Barnay S., Blanchin S.,
RA Beckerich J.M., Beyne E., Bleykasten C., Boisrame A., Boyer J.,
RA Cattolico L., Confanioleri F., de Daruvar A., Despons L., Fabre E.,
RA Fairhead C., Ferry-Dumazet H., Groppi A., Hantraye F., Hennequin C.,
RA Jauniaux N., Joyet P., Kachouri R., Kerrest A., Koszul R., Lemaire M.,
RA Lesur I., Ma L., Muller H., Nicaud J.M., Nikolski M., Oztas S.,
RA Ozier-Kalogeropoulos O., Pellenz S., Potier S., Richard G.F., Straub M.L.,
RA Suleau A., Swennene D., Tekaia F., Wesolowski-Louvel M., Westhof E.,
RA Wirth B., Zeniou-Meyer M., Zivanovic I., Bolotin-Fukuhara M., Thierry A.,
RA Bouchier C., Caudron B., Scarpelli C., Gaillardin C., Weissenbach J.,
RA Wincker P., Souciet J.L.;
RT "Genome evolution in yeasts.";
RL Nature 430:35-44(2004).
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DR EMBL; CR382126; CAG98443.1; -; Genomic_DNA.
DR RefSeq; XP_455735.1; XM_455735.1.
DR AlphaFoldDB; Q6CK04; -.
DR STRING; 284590.Q6CK04; -.
DR PaxDb; 284590-Q6CK04; -.
DR GeneID; 2894990; -.
DR KEGG; kla:KLLA0_F14575g; -.
DR eggNOG; ENOG502R16K; Eukaryota.
DR HOGENOM; CLU_003021_0_0_1; -.
DR InParanoid; Q6CK04; -.
DR OMA; KAIFEYK; -.
DR Proteomes; UP000000598; Chromosome F.
DR CDD; cd11887; SH3_Bbc1; 1.
DR Gene3D; 2.30.30.40; SH3 Domains; 1.
DR InterPro; IPR035552; Mti1_SH3.
DR InterPro; IPR036028; SH3-like_dom_sf.
DR InterPro; IPR001452; SH3_domain.
DR PANTHER; PTHR46026; RHO-TYPE GUANINE NUCLEOTIDE EXCHANGE FACTOR, ISOFORM F; 1.
DR PANTHER; PTHR46026:SF1; RHO-TYPE GUANINE NUCLEOTIDE EXCHANGE FACTOR, ISOFORM F; 1.
DR Pfam; PF00018; SH3_1; 1.
DR SMART; SM00326; SH3; 1.
DR SUPFAM; SSF50044; SH3-domain; 1.
DR PROSITE; PS50002; SH3; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000000598};
KW SH3 domain {ECO:0000256|ARBA:ARBA00022443, ECO:0000256|PROSITE-
KW ProRule:PRU00192}.
FT DOMAIN 2..66
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT REGION 61..602
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 69..86
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 88..102
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 109..137
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 139..153
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 154..171
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 183..207
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 225..258
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 262..279
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 361..383
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 433..451
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 461..484
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 485..525
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 545..568
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 569..602
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 851 AA; 92786 MW; FB31B86EC44D0DC3 CRC64;
MSVPFKVEAL FPYTSDFEDD LPFSKGQIIT VLEIEDDEWF FGEFKDADGK TKQGIFPKGF
VSEPLKETAS EPAQEKQPEE KPNVETPVKI PETQTVNPNA AAATAPVQKG KVSQDNVRQL
RNSLSFQEGS GDTERSGFVN SDDLVKEAKS ESKMSLQQRI SMLQHMQKQQ QEQAETLHKR
KKSISSVSSP TGSVATASAT SPVNIEKRES YDASVIEDSD AENPEVDVST SSIHTAPPIP
NDTASIGSHP QRTYSIPEES VNENDDRDDN DENESSEDEN EEEQRRAALR EKMARLANAS
RYGMPNAYFN PFGMPMPSAD SSKTPTKSKK PKEESESPTE TSSLPTAVPV MPFADPSMLP
MFRKKTEEIA VETSGHAETP ENQADEESES SFVDGVDDAQ PAITGSVNYD KDPDFQHKDE
VPEGSQGLSG YESEDETTKK VEDEEEEAPS PTVPQRIRPT HVYTIDTSPG SPQTPQTPQA
TNAPQKLPAA PPIPSAPSVP PIPTGAPIPP VPSSVPVPPL PTKAPAPVLS VKTENTEQKL
PTKQPAAAPA PPVPSSGGPP PLPPSNAPQR RPSIQTIPGA ANSSPATPSS AAPQIPASFQ
PLRRTTTAKF EPGTIPELEF SKQSTWWLTK TVQADTVKPS KVKYIWESQD HIVERRNTNK
LVVRDFQFLF EDYSQIQAYV VYDPKNPIET AISHQDYIPS SSQSTGSDLL IKTIYENSNK
CVGKACHSFI PQILGPIDNL VPPIAQRTYG ITVFEHAYNT AIDEAALGKL VPGLILVARN
AEFTFDDGLT YSLGIETPFV AILKSVDLET QSLSVIEELG GECKVSMYPL ENLTKGKLKV
AKPVHRKDIG W
//
