ID Q6CNN6_KLULA Unreviewed; 493 AA.
AC Q6CNN6;
DT 16-AUG-2004, integrated into UniProtKB/TrEMBL.
DT 16-AUG-2004, sequence version 1.
DT 27-MAR-2024, entry version 130.
DE SubName: Full=KLLA0E11177p {ECO:0000313|EMBL:CAG99540.1};
GN ORFNames=KLLA0_E11177g {ECO:0000313|EMBL:CAG99540.1};
OS Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 /
OS NRRL Y-1140 / WM37) (Yeast) (Candida sphaerica).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Saccharomycetaceae; Kluyveromyces.
OX NCBI_TaxID=284590 {ECO:0000313|EMBL:CAG99540.1, ECO:0000313|Proteomes:UP000000598};
RN [1] {ECO:0000313|EMBL:CAG99540.1, ECO:0000313|Proteomes:UP000000598}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 /
RC WM37 {ECO:0000313|Proteomes:UP000000598};
RX PubMed=15229592; DOI=10.1038/nature02579;
RG Genolevures;
RA Dujon B., Sherman D., Fischer G., Durrens P., Casaregola S., Lafontaine I.,
RA de Montigny J., Marck C., Neuveglise C., Talla E., Goffard N., Frangeul L.,
RA Aigle M., Anthouard V., Babour A., Barbe V., Barnay S., Blanchin S.,
RA Beckerich J.M., Beyne E., Bleykasten C., Boisrame A., Boyer J.,
RA Cattolico L., Confanioleri F., de Daruvar A., Despons L., Fabre E.,
RA Fairhead C., Ferry-Dumazet H., Groppi A., Hantraye F., Hennequin C.,
RA Jauniaux N., Joyet P., Kachouri R., Kerrest A., Koszul R., Lemaire M.,
RA Lesur I., Ma L., Muller H., Nicaud J.M., Nikolski M., Oztas S.,
RA Ozier-Kalogeropoulos O., Pellenz S., Potier S., Richard G.F., Straub M.L.,
RA Suleau A., Swennene D., Tekaia F., Wesolowski-Louvel M., Westhof E.,
RA Wirth B., Zeniou-Meyer M., Zivanovic I., Bolotin-Fukuhara M., Thierry A.,
RA Bouchier C., Caudron B., Scarpelli C., Gaillardin C., Weissenbach J.,
RA Wincker P., Souciet J.L.;
RT "Genome evolution in yeasts.";
RL Nature 430:35-44(2004).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR EMBL; CR382125; CAG99540.1; -; Genomic_DNA.
DR RefSeq; XP_454453.1; XM_454453.1.
DR AlphaFoldDB; Q6CNN6; -.
DR STRING; 284590.Q6CNN6; -.
DR PaxDb; 284590-Q6CNN6; -.
DR GeneID; 2893772; -.
DR KEGG; kla:KLLA0_E11177g; -.
DR eggNOG; KOG1009; Eukaryota.
DR HOGENOM; CLU_010127_5_1_1; -.
DR InParanoid; Q6CNN6; -.
DR OMA; QIYWHES; -.
DR Proteomes; UP000000598; Chromosome E.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0006335; P:DNA replication-dependent chromatin assembly; IEA:InterPro.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 2.
DR InterPro; IPR024977; Apc4-like_WD40_dom.
DR InterPro; IPR045145; PTHR15271.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR InterPro; IPR001680; WD40_rpt.
DR PANTHER; PTHR15271; CHROMATIN ASSEMBLY FACTOR 1 SUBUNIT B; 1.
DR PANTHER; PTHR15271:SF4; CHROMATIN ASSEMBLY FACTOR 1 SUBUNIT B; 1.
DR Pfam; PF12894; ANAPC4_WD40; 1.
DR Pfam; PF00400; WD40; 3.
DR SMART; SM00320; WD40; 5.
DR SUPFAM; SSF50978; WD40 repeat-like; 1.
DR PROSITE; PS50082; WD_REPEATS_2; 2.
DR PROSITE; PS50294; WD_REPEATS_REGION; 1.
PE 4: Predicted;
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000000598};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW WD repeat {ECO:0000256|ARBA:ARBA00022574, ECO:0000256|PROSITE-
KW ProRule:PRU00221}.
FT REPEAT 67..99
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT DOMAIN 124..185
FT /note="Anaphase-promoting complex subunit 4-like WD40"
FT /evidence="ECO:0000259|Pfam:PF12894"
FT REPEAT 131..172
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REGION 424..493
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 424..470
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 493 AA; 55177 MW; BCC70519CEAA6E03 CRC64;
MVQSESLQIY WHDSHPIYSL CFQPLSETNQ NTRRLFTSGG DNKIRVWQLN ESENDGKIET
IDFLSSLTQH EQAVNVCRFN KQGDTLATAG DDGLLLLWKK NETMVKEFGV DDDEFQDFKE
SWAVWKRLRS GSASNAEIYD ISWNPQGTCI AIASLDNTVR VFNVDQGKVV GHITEHNHYV
QGIVWDPQGE FIVSQSADRS LAICKMIYED NEVKGLQLVN KILKSELPRR KNPGEKELDF
DKSKVTFLFH NETLPSFFRR LSMSPCGSLL CVPAGVFRND EQTDASNNNP EYANAVYIYT
RASLTSNSNK PVFSLPFLQK PALVVKFNPI MYETASEWVK APYTLVFAVA TTNEVLVYDT
QNTSPIAIAG NLHYTPITDL AWSQDGTLLM ISSTDGFCSY IHFTDNDFGT PLKDQSIPIL
TKELESQSQS QSQPESSQKA SIVNLSTGAA ETPNPSPAKR SISQLVSEAA TTVGKEKLKR
RVQPTLVTSD QPK
//
