GenomeNet

Database: UniProt
Entry: Q6CX91
LinkDB: Q6CX91
Original site: Q6CX91 
ID   SET5_KLULA              Reviewed;         492 AA.
AC   Q6CX91;
DT   18-MAR-2008, integrated into UniProtKB/Swiss-Prot.
DT   16-AUG-2004, sequence version 1.
DT   10-APR-2019, entry version 70.
DE   RecName: Full=Potential protein lysine methyltransferase SET5;
DE            EC=2.1.1.-;
DE   AltName: Full=SET domain-containing protein 5;
GN   Name=SET5; OrderedLocusNames=KLLA0A10241g;
OS   Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC
OS   1267 / NRRL Y-1140 / WM37) (Yeast) (Candida sphaerica).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina;
OC   Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Kluyveromyces.
OX   NCBI_TaxID=284590;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 /
RC   WM37;
RX   PubMed=15229592; DOI=10.1038/nature02579;
RA   Dujon B., Sherman D., Fischer G., Durrens P., Casaregola S.,
RA   Lafontaine I., de Montigny J., Marck C., Neuveglise C., Talla E.,
RA   Goffard N., Frangeul L., Aigle M., Anthouard V., Babour A., Barbe V.,
RA   Barnay S., Blanchin S., Beckerich J.-M., Beyne E., Bleykasten C.,
RA   Boisrame A., Boyer J., Cattolico L., Confanioleri F., de Daruvar A.,
RA   Despons L., Fabre E., Fairhead C., Ferry-Dumazet H., Groppi A.,
RA   Hantraye F., Hennequin C., Jauniaux N., Joyet P., Kachouri R.,
RA   Kerrest A., Koszul R., Lemaire M., Lesur I., Ma L., Muller H.,
RA   Nicaud J.-M., Nikolski M., Oztas S., Ozier-Kalogeropoulos O.,
RA   Pellenz S., Potier S., Richard G.-F., Straub M.-L., Suleau A.,
RA   Swennen D., Tekaia F., Wesolowski-Louvel M., Westhof E., Wirth B.,
RA   Zeniou-Meyer M., Zivanovic Y., Bolotin-Fukuhara M., Thierry A.,
RA   Bouchier C., Caudron B., Scarpelli C., Gaillardin C., Weissenbach J.,
RA   Wincker P., Souciet J.-L.;
RT   "Genome evolution in yeasts.";
RL   Nature 430:35-44(2004).
CC   -!- FUNCTION: Putative protein lysine methyltransferase.
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}. Nucleus
CC       {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the class V-like SAM-binding
CC       methyltransferase superfamily. Histone-lysine methyltransferase
CC       family. SET5 subfamily. {ECO:0000255|PROSITE-ProRule:PRU00190}.
DR   EMBL; CR382121; CAH03036.1; -; Genomic_DNA.
DR   RefSeq; XP_451448.1; XM_451448.1.
DR   ProteinModelPortal; Q6CX91; -.
DR   SMR; Q6CX91; -.
DR   STRING; 28985.XP_451448.1; -.
DR   PRIDE; Q6CX91; -.
DR   EnsemblFungi; CAH03036; CAH03036; KLLA0_A10241g.
DR   GeneID; 2896390; -.
DR   KEGG; kla:KLLA0_A10241g; -.
DR   eggNOG; KOG2084; Eukaryota.
DR   eggNOG; COG2940; LUCA.
DR   HOGENOM; HOG000074714; -.
DR   InParanoid; Q6CX91; -.
DR   OMA; WSVSEKR; -.
DR   Proteomes; UP000000598; Chromosome A.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0000790; C:nuclear chromatin; IEA:EnsemblFungi.
DR   GO; GO:0008757; F:S-adenosylmethionine-dependent methyltransferase activity; IEA:EnsemblFungi.
DR   GO; GO:0034968; P:histone lysine methylation; IEA:EnsemblFungi.
DR   InterPro; IPR001214; SET_dom.
DR   Pfam; PF00856; SET; 1.
DR   SMART; SM00317; SET; 1.
DR   PROSITE; PS50280; SET; 1.
PE   3: Inferred from homology;
KW   Complete proteome; Cytoplasm; Methyltransferase; Nucleus;
KW   Reference proteome; S-adenosyl-L-methionine; Transferase.
FT   CHAIN         1    492       Potential protein lysine
FT                                methyltransferase SET5.
FT                                /FTId=PRO_0000324469.
FT   DOMAIN      113    384       SET. {ECO:0000255|PROSITE-
FT                                ProRule:PRU00190}.
SQ   SEQUENCE   492 AA;  56020 MW;  968851A5E63E5520 CRC64;
     MVHLKLETLR LNDEDQSTGS SLITPSRTQL CDEVVRWWKE EPAAEDMLID TLYEHLIRRR
     SNWSVTKDEL YQALKSHKLY TPELNELDSY TGDIRPSTVT DADIAQLNKK LLDKVTIADT
     EFGKGLVATD DIRKGGLVFH EQLPLTVIPQ LDKQPLVSRG KCCGLCSAFT TLSSQLIIKN
     NLDCNMCNTI WCSKQCKKLD TTHSVLKHAT SRNSLCNSSN WIKFENFCLQ ESLVAAYAVG
     VIYARHVMQP TSNLWKLFTS LCSVSQRVRW QASDSINVGG TFDASCNGKL YADVSAPNME
     TQWSDAFEMF AKSFPKCDMD YEDFLNLTGT FNLNQIMGQV YPLVAHINHS CEPNVRYELE
     PKHGIKLYAR KDIKKGEQLR LTYVNPLHGV TLRRRELRVN YGFLCHCPRC CQEWEKRQKI
     VSDPSNHAIS SEAAHSSTTA RRKSSMKSCR PSLKELLENG DEFDLEIPSD VNSKRRMSVR
     FNSHVTLAVE EE
//
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