ID Q6DAT8_PECAS Unreviewed; 355 AA.
AC Q6DAT8;
DT 16-AUG-2004, integrated into UniProtKB/TrEMBL.
DT 16-AUG-2004, sequence version 1.
DT 27-MAR-2024, entry version 87.
DE RecName: Full=lipopolysaccharide heptosyltransferase II {ECO:0000256|ARBA:ARBA00044042};
DE EC=2.4.99.24 {ECO:0000256|ARBA:ARBA00044042};
GN Name=waaF {ECO:0000313|EMBL:CAG73084.1};
GN Synonyms=rfaF {ECO:0000313|EMBL:CAG73084.1};
GN OrderedLocusNames=ECA0164 {ECO:0000313|EMBL:CAG73084.1};
OS Pectobacterium atrosepticum (strain SCRI 1043 / ATCC BAA-672) (Erwinia
OS carotovora subsp. atroseptica).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC Pectobacteriaceae; Pectobacterium.
OX NCBI_TaxID=218491 {ECO:0000313|EMBL:CAG73084.1, ECO:0000313|Proteomes:UP000007966};
RN [1] {ECO:0000313|EMBL:CAG73084.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=SCRI1043 {ECO:0000313|EMBL:CAG73084.1};
RA Bell K.S., Sebaihia M., Pritchard L., Holden M., Hyman L.J., Holeva M.C.,
RA Thomson N.R., Bentley S.D., Churcher C., Mungall K., Atkin R., Bason N.,
RA Brooks K., Chillingworth T., Clark K., Doggett J., Fraser A., Hance Z.,
RA Hauser H., Jagels K., Moule S., Norbertczak H., Ormond D., Price C.,
RA Quail M.A., Sanders M., Walker D., Whitehead S., Salmond G.P.C.,
RA Birch P.R.J., Barrell B.G., Parkhill J., Toth I.K.;
RT "The genome sequence of the enterobacterial phytopathogen Erwinia
RT carotovora subsp. atroseptica SCRI1043 and functional genomic
RT identification of novel virulence factors.";
RL Submitted (FEB-2004) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ADP-L-glycero-beta-D-manno-heptose + an L-alpha-D-Hep-(1->5)-
CC [alpha-Kdo-(2->4)]-alpha-Kdo-(2->6)-lipid A = ADP + an L-alpha-D-Hep-
CC (1->3)-L-alpha-D-Hep-(1->5)-[alpha-Kdo-(2->4)]-alpha-Kdo-(2->6)-lipid
CC A + H(+); Xref=Rhea:RHEA:74071, ChEBI:CHEBI:15378, ChEBI:CHEBI:61506,
CC ChEBI:CHEBI:193068, ChEBI:CHEBI:193069, ChEBI:CHEBI:456216;
CC EC=2.4.99.24; Evidence={ECO:0000256|ARBA:ARBA00043830};
CC -!- SIMILARITY: Belongs to the glycosyltransferase 9 family.
CC {ECO:0000256|ARBA:ARBA00043995}.
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DR EMBL; BX950851; CAG73084.1; -; Genomic_DNA.
DR RefSeq; WP_011091804.1; NC_004547.2.
DR AlphaFoldDB; Q6DAT8; -.
DR STRING; 218491.ECA0164; -.
DR KEGG; eca:ECA0164; -.
DR PATRIC; fig|218491.5.peg.165; -.
DR eggNOG; COG0859; Bacteria.
DR HOGENOM; CLU_038371_7_0_6; -.
DR OrthoDB; 9797795at2; -.
DR Proteomes; UP000007966; Chromosome.
DR GO; GO:0016757; F:glycosyltransferase activity; IEA:InterPro.
DR GO; GO:0009103; P:lipopolysaccharide biosynthetic process; IEA:InterPro.
DR CDD; cd03789; GT9_LPS_heptosyltransferase; 1.
DR Gene3D; 3.40.50.2000; Glycogen Phosphorylase B; 2.
DR InterPro; IPR002201; Glyco_trans_9.
DR InterPro; IPR011910; RfaF.
DR NCBIfam; TIGR02195; heptsyl_trn_II; 1.
DR PANTHER; PTHR30160:SF7; ADP-HEPTOSE--LPS HEPTOSYLTRANSFERASE 2; 1.
DR PANTHER; PTHR30160; TETRAACYLDISACCHARIDE 4'-KINASE-RELATED; 1.
DR Pfam; PF01075; Glyco_transf_9; 1.
DR SUPFAM; SSF53756; UDP-Glycosyltransferase/glycogen phosphorylase; 1.
PE 3: Inferred from homology;
KW Glycosyltransferase {ECO:0000256|ARBA:ARBA00022676};
KW Reference proteome {ECO:0000313|Proteomes:UP000007966};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000313|EMBL:CAG73084.1}.
SQ SEQUENCE 355 AA; 39228 MW; 06163BDE1312F089 CRC64;
MKILVIGPSW VGDMMMSHSL YRTLKAEHPE AVIDVMAPAW CRPLLARMPE VNQALAMPLG
HGALELGERR RLGVSLRDAG YDRAYVLPNS FKSALVPFFA NIPQRTGWRG EMRYGLLNDL
RVLDKTAFPL MVQRYAALAY DRSRIHRAED LPQPLLWPQL QVNQAEIADI TQAFDLSDER
PIIGFCPGAE FGPAKRWPHY HYAALAQSLI KRGYQIALFG SANDSSACDD ILQGLTEDAR
QHCANLAGKT SLEQAVVLIA ACHAVISNDS GLMHVAAALH RPLVALYGPS SPDFTPPLSH
QAEVIRLITG YHRVRKGDAE QGYHQSLIDI QPERVLSALD KHLILGVNRV PGADA
//
