ID Q6DKM5_XENLA Unreviewed; 146 AA.
AC Q6DKM5;
DT 16-AUG-2004, integrated into UniProtKB/TrEMBL.
DT 16-AUG-2004, sequence version 1.
DT 27-MAR-2024, entry version 90.
DE SubName: Full=Hemoglobin subunit gamma 2 S homeolog {ECO:0000313|RefSeq:NP_001167483.1};
GN Name=hbg2.S {ECO:0000313|RefSeq:NP_001167483.1,
GN ECO:0000313|Xenbase:XB-GENE-6252874};
GN Synonyms=hbb2 {ECO:0000313|RefSeq:NP_001167483.1}, hbg2
GN {ECO:0000313|Xenbase:XB-GENE-6252874}, hbg2-a
GN {ECO:0000313|RefSeq:NP_001167483.1}, hbg2-b
GN {ECO:0000313|RefSeq:NP_001167483.1}, hbg2.L
GN {ECO:0000313|RefSeq:NP_001167483.1};
OS Xenopus laevis (African clawed frog).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus.
OX NCBI_TaxID=8355 {ECO:0000313|EMBL:AAH71139.1};
RN [1] {ECO:0000313|RefSeq:NP_001167483.1}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=6298748; DOI=10.1093/nar/11.5.1543;
RA Knochel W., Meyerhof W., Hummel S., Grundmann U.;
RT "Molecular cloning and sequencing of mRNAs coding for minor adult globin
RT polypeptides of Xenopus laevis.";
RL Nucleic Acids Res. 11:1543-1553(1983).
RN [2] {ECO:0000313|RefSeq:NP_001167483.1}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=12454917; DOI=10.1002/dvdy.10174;
RA Klein S.L., Strausberg R.L., Wagner L., Pontius J., Clifton S.W.,
RA Richardson P.;
RT "Genetic and genomic tools for Xenopus research: The NIH Xenopus
RT initiative.";
RL Dev. Dyn. 225:384-391(2002).
RN [3] {ECO:0000313|EMBL:AAH71139.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Lung {ECO:0000313|EMBL:AAH71139.1};
RG NIH - Xenopus Gene Collection (XGC) project;
RL Submitted (MAY-2004) to the EMBL/GenBank/DDBJ databases.
RN [4] {ECO:0000313|RefSeq:NP_001167483.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBUNIT: Heterotetramer of two alpha chains and two beta chains.
CC {ECO:0000256|ARBA:ARBA00011125}.
CC -!- SIMILARITY: Belongs to the globin family.
CC {ECO:0000256|ARBA:ARBA00008705, ECO:0000256|PROSITE-ProRule:PRU00238,
CC ECO:0000256|RuleBase:RU000356}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; BC071139; AAH71139.1; -; mRNA.
DR RefSeq; NP_001167483.1; NM_001174012.1.
DR STRING; 8355.Q6DKM5; -.
DR PaxDb; 8355-Q6DKM5; -.
DR DNASU; 100381042; -.
DR GeneID; 100381042; -.
DR KEGG; xla:100381042; -.
DR AGR; Xenbase:XB-GENE-6252874; -.
DR CTD; 100381042; -.
DR Xenbase; XB-GENE-6252874; hbg2.S.
DR OMA; YFAHFGN; -.
DR OrthoDB; 5356926at2759; -.
DR Proteomes; UP000186698; Chromosome 9_10S.
DR Bgee; 100381042; Expressed in liver and 15 other cell types or tissues.
DR GO; GO:0005833; C:hemoglobin complex; IEA:InterPro.
DR GO; GO:0020037; F:heme binding; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0019825; F:oxygen binding; IEA:InterPro.
DR GO; GO:0005344; F:oxygen carrier activity; IEA:UniProtKB-KW.
DR CDD; cd08925; Hb-beta-like; 1.
DR Gene3D; 1.10.490.10; Globins; 1.
DR InterPro; IPR000971; Globin.
DR InterPro; IPR009050; Globin-like_sf.
DR InterPro; IPR012292; Globin/Proto.
DR InterPro; IPR002337; Hemoglobin_b.
DR PANTHER; PTHR11442; HEMOGLOBIN FAMILY MEMBER; 1.
DR PANTHER; PTHR11442:SF7; HEMOGLOBIN SUBUNIT EPSILON; 1.
DR Pfam; PF00042; Globin; 1.
DR PRINTS; PR00814; BETAHAEM.
DR SUPFAM; SSF46458; Globin-like; 1.
DR PROSITE; PS01033; GLOBIN; 1.
PE 2: Evidence at transcript level;
KW Heme {ECO:0000256|RuleBase:RU000356}; Iron {ECO:0000256|RuleBase:RU000356};
KW Metal-binding {ECO:0000256|RuleBase:RU000356};
KW Oxygen transport {ECO:0000256|ARBA:ARBA00022621,
KW ECO:0000256|RuleBase:RU000356};
KW Reference proteome {ECO:0000313|Proteomes:UP000186698};
KW Transport {ECO:0000256|RuleBase:RU000356}.
FT DOMAIN 3..146
FT /note="Globin family profile"
FT /evidence="ECO:0000259|PROSITE:PS01033"
SQ SEQUENCE 146 AA; 16197 MW; AADB5C2CA8B10506 CRC64;
MGLTAQEKQL INSTWGKINA KAIGKEALGR LLNTFPWTQR YFSSFGNLSS AEAIFHNEAV
AAHGEKVVTS VGEAIKHMDD IKGYYAQLSK HHSETLHVDP ANFKRFGGCL SITLAHHFGE
EYTPELHAAY EHLFDVIADA LGRGYH
//
