ID   CPB3_CAERE              Reviewed;         766 AA.
AC   Q6E3D4;
DT   23-NOV-2004, integrated into UniProtKB/Swiss-Prot.
DT   16-AUG-2004, sequence version 1.
DT   27-MAR-2024, entry version 78.
DE   RecName: Full=Cytoplasmic polyadenylation element-binding protein 3;
GN   Name=cpb-3;
OS   Caenorhabditis remanei (Caenorhabditis vulgaris).
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC   Caenorhabditis.
OX   NCBI_TaxID=31234;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA / MRNA].
RX   PubMed=15231741; DOI=10.1101/gr.2639304;
RA   Cho S., Jin S.W., Cohen A., Ellis R.E.;
RT   "A phylogeny of Caenorhabditis reveals frequent loss of introns during
RT   nematode evolution.";
RL   Genome Res. 14:1207-1220(2004).
CC   -!- FUNCTION: Cytoplasmic polyadenylation element binding protein that
CC       binds to and regulates the translation of specific mRNAs.
CC       {ECO:0000250}.
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DR   EMBL; AY589637; AAT72444.1; -; Genomic_DNA.
DR   EMBL; AY589607; AAT72415.1; -; mRNA.
DR   RefSeq; XP_003111092.1; XM_003111044.1.
DR   AlphaFoldDB; Q6E3D4; -.
DR   SMR; Q6E3D4; -.
DR   EnsemblMetazoa; CRE03781.1; CRE03781.1; WBGene00066597.
DR   eggNOG; KOG0129; Eukaryota.
DR   HOGENOM; CLU_377774_0_0_1; -.
DR   OMA; MFCEDES; -.
DR   OrthoDB; 2897681at2759; -.
DR   GO; GO:0003730; F:mRNA 3'-UTR binding; IEA:InterPro.
DR   GO; GO:0045182; F:translation regulator activity; IEA:InterPro.
DR   CDD; cd19757; Bbox1; 1.
DR   CDD; cd12723; RRM1_CPEB1; 1.
DR   CDD; cd12725; RRM2_CPEB1; 1.
DR   Gene3D; 3.30.70.330; -; 2.
DR   Gene3D; 4.10.640.40; Cytoplasmic polyadenylation element-binding protein, ZZ domain; 1.
DR   InterPro; IPR032296; CEBP_ZZ.
DR   InterPro; IPR038446; CEBP_ZZ_sf.
DR   InterPro; IPR034819; CPEB.
DR   InterPro; IPR034977; CPEB1_RRM1.
DR   InterPro; IPR012677; Nucleotide-bd_a/b_plait_sf.
DR   InterPro; IPR035979; RBD_domain_sf.
DR   InterPro; IPR000504; RRM_dom.
DR   PANTHER; PTHR12566; CYTOPLASMIC POLYADENYLATION ELEMENT BINDING PROTEIN CPEB; 1.
DR   PANTHER; PTHR12566:SF9; CYTOPLASMIC POLYADENYLATION ELEMENT-BINDING PROTEIN 1; 1.
DR   Pfam; PF16366; CEBP_ZZ; 1.
DR   Pfam; PF16367; RRM_7; 1.
DR   SMART; SM00360; RRM; 2.
DR   SUPFAM; SSF54928; RNA-binding domain, RBD; 1.
PE   2: Evidence at transcript level;
KW   RNA-binding.
FT   CHAIN           1..766
FT                   /note="Cytoplasmic polyadenylation element-binding protein
FT                   3"
FT                   /id="PRO_0000081519"
FT   DOMAIN          310..332
FT                   /note="RRM"
FT   REGION          1..35
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          131..179
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          216..299
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          578..602
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        19..33
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        136..152
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        227..289
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   766 AA;  85248 MW;  49AED8DB9D544CAF CRC64;
     MSQEEVPGEI PGDIAIEKAE NTVQDDVEAK NTSETKKTIP PMLNVEKVDV AAVGEKSPAP
     VSVYDLFKKY QKPDVKSDSE DMNIGFDQLT TDEKNGFLRK LQMLTVGNKK TLKVPGESTP
     SPASRLLKKF VPSRRPSTEN KSCESPSRFS LFGKSNKKAP ELERPMNGGQ PRKKSARRLN
     FGKEIEERTE TDFQNNRVVA AMTREYEKIV TLKGVPVPIN KPPRQQGPRG SLETPTDSPA
     KTETSSISKS YGSDYQSSRD RYTSINEDSL TKKRISTPNR GQGLSNRDNA TWHGELPPRD
     YTSPTFSRKI FVGGVPWDIT EAALKDSFGE FGSCAVEWPG HEARYRNAQS NTASLNLRNQ
     SKYTGQAATG YVYMIFEDER AVASLLHECS QEIGGAGEWY FKIRAQRSKS TEIRQVQIIP
     WVTSDSMFCE DESLLEVGIE PKRTVFVGAL HGMMTAQVLH SIMEDCFGSV ECVQLDTDKF
     KYPIGSGRVT FREHGAYFKA IEMGYLHVHT SKFRKRVQID PFLESTNCMV CTTELAHCFC
     RNRNCFKYYC HTCWAVDHGH GHDGEVHVPV IVPSSASKAF SGPNRRSHLS SNSPSKPASL
     MSSSNSQVAH MVSPAYPVLV GAPAQNLSAL YGYIQNSQQM MITPAAVYEP PMTPSPNEMK
     RRSFPEFQPQ PTVFFNSTPM MTPQKGVPCS DGSAVPAYYA NSAAFLTPPS SYYNSPSHST
     SSNLSPQQPQ QYYGANLYYG YMPQMSYDGG PNQSAMHLPH TPNYQQ
//