GenomeNet

Database: UniProt
Entry: Q6EU14
LinkDB: Q6EU14
Original site: Q6EU14 
ID   AGO1A_ORYSJ             Reviewed;        1082 AA.
AC   Q6EU14; A0A0N7KFV1;
DT   07-JUL-2009, integrated into UniProtKB/Swiss-Prot.
DT   16-AUG-2004, sequence version 1.
DT   16-OCT-2019, entry version 89.
DE   RecName: Full=Protein argonaute 1A;
DE            Short=OsAGO1a;
GN   Name=AGO1A; OrderedLocusNames=Os02g0672200, LOC_Os02g45070;
GN   ORFNames=OJ1493_H11.13;
OS   Oryza sativa subsp. japonica (Rice).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC   Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX   NCBI_TaxID=39947;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Nipponbare;
RX   PubMed=16100779; DOI=10.1038/nature03895;
RG   International rice genome sequencing project (IRGSP);
RT   "The map-based sequence of the rice genome.";
RL   Nature 436:793-800(2005).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Nipponbare;
RX   PubMed=18089549; DOI=10.1093/nar/gkm978;
RG   The rice annotation project (RAP);
RT   "The rice annotation project database (RAP-DB): 2008 update.";
RL   Nucleic Acids Res. 36:D1028-D1033(2008).
RN   [3]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Nipponbare;
RX   PubMed=24280374; DOI=10.1186/1939-8433-6-4;
RA   Kawahara Y., de la Bastide M., Hamilton J.P., Kanamori H.,
RA   McCombie W.R., Ouyang S., Schwartz D.C., Tanaka T., Wu J., Zhou S.,
RA   Childs K.L., Davidson R.M., Lin H., Quesada-Ocampo L.,
RA   Vaillancourt B., Sakai H., Lee S.S., Kim J., Numa H., Itoh T.,
RA   Buell C.R., Matsumoto T.;
RT   "Improvement of the Oryza sativa Nipponbare reference genome using
RT   next generation sequence and optical map data.";
RL   Rice 6:4-4(2013).
RN   [4]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=cv. Nipponbare;
RX   PubMed=12869764; DOI=10.1126/science.1081288;
RG   The rice full-length cDNA consortium;
RT   "Collection, mapping, and annotation of over 28,000 cDNA clones from
RT   japonica rice.";
RL   Science 301:376-379(2003).
RN   [5]
RP   GENE FAMILY, AND NOMENCLATURE.
RX   PubMed=18826656; DOI=10.1186/1471-2164-9-451;
RA   Kapoor M., Arora R., Lama T., Nijhawan A., Khurana J.P., Tyagi A.K.,
RA   Kapoor S.;
RT   "Genome-wide identification, organization and phylogenetic analysis of
RT   dicer-like, argonaute and RNA-dependent RNA polymerase gene families
RT   and their expression analysis during reproductive development and
RT   stress in rice.";
RL   BMC Genomics 9:451-451(2008).
CC   -!- FUNCTION: Probably involved in the RNA silencing pathway. May bind
CC       to short RNAs such as microRNAs (miRNAs) or short interfering RNAs
CC       (siRNAs), and represses the translation of mRNAs which are
CC       complementary to them (By similarity). {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the argonaute family. Ago subfamily.
CC       {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AK111553; Type=Frameshift; Evidence={ECO:0000305};
DR   EMBL; AP004188; BAD27856.1; -; Genomic_DNA.
DR   EMBL; AP008208; BAF09618.1; -; Genomic_DNA.
DR   EMBL; AP014958; BAS80241.1; -; Genomic_DNA.
DR   EMBL; AK111553; -; NOT_ANNOTATED_CDS; mRNA.
DR   RefSeq; XP_015626096.1; XM_015770610.1.
DR   SMR; Q6EU14; -.
DR   STRING; 4530.OS02T0672200-01; -.
DR   PaxDb; Q6EU14; -.
DR   PRIDE; Q6EU14; -.
DR   EnsemblPlants; Os02t0672200-01; Os02t0672200-01; Os02g0672200.
DR   GeneID; 4330281; -.
DR   Gramene; Os02t0672200-01; Os02t0672200-01; Os02g0672200.
DR   KEGG; osa:4330281; -.
DR   eggNOG; KOG1041; Eukaryota.
DR   eggNOG; ENOG410XP07; LUCA.
DR   HOGENOM; HOG000116043; -.
DR   InParanoid; Q6EU14; -.
DR   KO; K11593; -.
DR   OMA; FPIDNHG; -.
DR   OrthoDB; 159407at2759; -.
DR   Proteomes; UP000059680; Chromosome 2.
DR   ExpressionAtlas; Q6EU14; baseline and differential.
DR   Genevisible; Q6EU14; OS.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:0031047; P:gene silencing by RNA; IEA:UniProtKB-KW.
DR   Gene3D; 3.30.420.10; -; 1.
DR   InterPro; IPR014811; ArgoL1.
DR   InterPro; IPR032472; ArgoL2.
DR   InterPro; IPR024357; Argonaut_Gly-rich.
DR   InterPro; IPR032473; Argonaute_Mid_dom.
DR   InterPro; IPR032474; Argonaute_N.
DR   InterPro; IPR003100; PAZ_dom.
DR   InterPro; IPR036085; PAZ_dom_sf.
DR   InterPro; IPR003165; Piwi.
DR   InterPro; IPR012337; RNaseH-like_sf.
DR   InterPro; IPR036397; RNaseH_sf.
DR   Pfam; PF08699; ArgoL1; 1.
DR   Pfam; PF16488; ArgoL2; 1.
DR   Pfam; PF16487; ArgoMid; 1.
DR   Pfam; PF16486; ArgoN; 1.
DR   Pfam; PF12764; Gly-rich_Ago1; 1.
DR   Pfam; PF02170; PAZ; 1.
DR   Pfam; PF02171; Piwi; 1.
DR   SMART; SM01163; DUF1785; 1.
DR   SMART; SM00949; PAZ; 1.
DR   SMART; SM00950; Piwi; 1.
DR   SUPFAM; SSF101690; SSF101690; 1.
DR   SUPFAM; SSF53098; SSF53098; 1.
DR   PROSITE; PS50821; PAZ; 1.
DR   PROSITE; PS50822; PIWI; 1.
PE   2: Evidence at transcript level;
KW   Complete proteome; Reference proteome; RNA-mediated gene silencing.
FT   CHAIN         1   1082       Protein argonaute 1A.
FT                                /FTId=PRO_0000378425.
FT   DOMAIN      419    533       PAZ. {ECO:0000255|PROSITE-
FT                                ProRule:PRU00142}.
FT   DOMAIN      709   1030       Piwi. {ECO:0000255|PROSITE-
FT                                ProRule:PRU00150}.
FT   COMPBIAS     29    130       Gly-rich.
FT   CONFLICT    163    163       G -> A (in Ref. 4; AK111553).
FT                                {ECO:0000305}.
FT   CONFLICT    280    280       K -> E (in Ref. 4; AK111553).
FT                                {ECO:0000305}.
SQ   SEQUENCE   1082 AA;  120449 MW;  FAE0E9368D02B91D CRC64;
     MAFQLDNGYY SHQALAMMRK KKTEPRNAGE SSGTQQATGA PGRGPSQRPE RAQQHGGGGW
     QPANPQYAQQ AGRGGGQHQG RGGRYQGRGG PTSHQPGGGP VEYQAHEYYG RGVQRQGGMP
     QHRSGSGGHG VPASPSRTVP ELHQASQDQY QATVVAPSPS RTGPSSLPVE ASSEEVQHQF
     QELAIQGQSP TSQAIQPAPP SSKSVRFPMR PGKGTFGDRC IVKANHFFAE LPDKDLHQYD
     VSITPEVPSR GVNRAVIGEI VTQYRQSHLG GRLPVYDGRK SLYTAGPLPF TSRTFDVILQ
     DEEESLAVGQ GAQRRERPFK VVIKFAARAD LHHLAMFLAG RQADAPQEAL QVLDIVLREL
     PTARYSPVAR SFYSPNLGRR QQLGEGLESW RGFYQSIRPT QMGLSLNIDM SSTAFIEPLP
     VIDFVAQLLN RDISVRPLSD ADRVKIKKAL RGVKVEVTHR GNMRRKYRIS GLTSQATREL
     SFPIDNHGTV KTVVQYFQET YGFNIKHTTL PCLQVGNQQR PNYLPMEVCK IVEGQRYSKR
     LNEKQITALL KVTCQRPQER ELDILQTVHH NAYHQDPYAQ EFGIRIDERL ASVEARVLPP
     PWLKYHDSGR EKDVLPRIGQ WNMMNKKMVN GGRVNNWTCI NFSRHVQDNA ARSFCRELAI
     MCQISGMDFS IDPVVPLVTA RPEHVERALK ARYQEAMNIL KPQGGELDLL IAILPDNNGS
     LYGDLKRICE TDLGLVSQCC LTKHVFKMSK QYLANVALKI NVKVGGRNTV LVDALTRRIP
     LVSDRPTIIF GADVTHPHPG EDSSPSIAAV VASQDWPEVT KYAGLVSAQA HRQELIQDLF
     KVWKDPQRGT VSGGMIRELL ISFKRATGQK PQRIIFYRDG VSEGQFYQVL FYELDAIRKA
     CASLEADYQP PVTFVVVQKR HHTRLFANNH KDQRTVDRSG NILPGTVVDS KICHPTEFDF
     YLCSHAGIQG TSRPAHYHVL WDENKFTADG LQTLTNNLCY TYARCTRSVS IVPPAYYAHL
     AAFRARFYME PDTSDSGSMA SGAHTRGGGP LPGARSTKPA GNVAVRPLPD LKENVKRVMF
     YC
//
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