ID Q6FNY0_CANGA Unreviewed; 572 AA.
AC Q6FNY0;
DT 19-JUL-2004, integrated into UniProtKB/TrEMBL.
DT 19-JUL-2004, sequence version 1.
DT 27-MAR-2024, entry version 111.
DE SubName: Full=Candida glabrata strain CBS138 chromosome J complete sequence {ECO:0000313|EMBL:CAG61015.1};
GN OrderedLocusNames=CAGL0J08184g {ECO:0000313|CGD:CAL0133096,
GN ECO:0000313|EMBL:CAG61015.1};
OS Candida glabrata (strain ATCC 2001 / BCRC 20586 / JCM 3761 / NBRC 0622 /
OS NRRL Y-65 / CBS 138) (Yeast) (Nakaseomyces glabratus).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Saccharomycetaceae; Nakaseomyces.
OX NCBI_TaxID=284593 {ECO:0000313|EMBL:CAG61015.1, ECO:0000313|Proteomes:UP000002428};
RN [1] {ECO:0000313|EMBL:CAG61015.1, ECO:0000313|Proteomes:UP000002428}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65
RC {ECO:0000313|Proteomes:UP000002428};
RX PubMed=15229592; DOI=10.1038/nature02579;
RG Genolevures;
RA Dujon B., Sherman D., Fischer G., Durrens P., Casaregola S., Lafontaine I.,
RA de Montigny J., Marck C., Neuveglise C., Talla E., Goffard N., Frangeul L.,
RA Aigle M., Anthouard V., Babour A., Barbe V., Barnay S., Blanchin S.,
RA Beckerich J.M., Beyne E., Bleykasten C., Boisrame A., Boyer J.,
RA Cattolico L., Confanioleri F., de Daruvar A., Despons L., Fabre E.,
RA Fairhead C., Ferry-Dumazet H., Groppi A., Hantraye F., Hennequin C.,
RA Jauniaux N., Joyet P., Kachouri R., Kerrest A., Koszul R., Lemaire M.,
RA Lesur I., Ma L., Muller H., Nicaud J.M., Nikolski M., Oztas S.,
RA Ozier-Kalogeropoulos O., Pellenz S., Potier S., Richard G.F., Straub M.L.,
RA Suleau A., Swennene D., Tekaia F., Wesolowski-Louvel M., Westhof E.,
RA Wirth B., Zeniou-Meyer M., Zivanovic I., Bolotin-Fukuhara M., Thierry A.,
RA Bouchier C., Caudron B., Scarpelli C., Gaillardin C., Weissenbach J.,
RA Wincker P., Souciet J.L.;
RT "Genome evolution in yeasts.";
RL Nature 430:35-44(2004).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the amino acid-polyamine-organocation (APC)
CC superfamily. YAT (TC 2.A.3.10) family. {ECO:0000256|ARBA:ARBA00006983}.
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DR EMBL; CR380956; CAG61015.1; -; Genomic_DNA.
DR RefSeq; XP_448064.1; XM_448064.1.
DR AlphaFoldDB; Q6FNY0; -.
DR STRING; 284593.Q6FNY0; -.
DR EnsemblFungi; CAGL0J08184g-T; CAGL0J08184g-T-p1; CAGL0J08184g.
DR GeneID; 2889921; -.
DR KEGG; cgr:CAGL0J08184g; -.
DR CGD; CAL0133096; CAGL0J08184g.
DR VEuPathDB; FungiDB:CAGL0J08184g; -.
DR eggNOG; KOG1286; Eukaryota.
DR HOGENOM; CLU_007946_12_1_1; -.
DR InParanoid; Q6FNY0; -.
DR OMA; SEFWFSG; -.
DR Proteomes; UP000002428; Chromosome J.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015174; F:basic amino acid transmembrane transporter activity; IEA:EnsemblFungi.
DR Gene3D; 1.20.1740.10; Amino acid/polyamine transporter I; 1.
DR InterPro; IPR004841; AA-permease/SLC12A_dom.
DR InterPro; IPR004762; Amino_acid_permease_fungi.
DR InterPro; IPR004840; Amoino_acid_permease_CS.
DR NCBIfam; TIGR00913; 2A0310; 1.
DR PANTHER; PTHR43341; AMINO ACID PERMEASE; 1.
DR PANTHER; PTHR43341:SF4; ARGININE PERMEASE CAN1-RELATED; 1.
DR Pfam; PF00324; AA_permease; 1.
DR PIRSF; PIRSF006060; AA_transporter; 1.
DR PROSITE; PS00218; AMINO_ACID_PERMEASE_1; 1.
PE 3: Inferred from homology;
KW Amino-acid transport {ECO:0000256|ARBA:ARBA00022970};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000002428};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 75..93
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 99..118
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 183..204
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 210..234
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 306..327
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 359..384
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 404..421
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 433..454
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 475..497
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 509..530
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 74..538
FT /note="Amino acid permease/ SLC12A"
FT /evidence="ECO:0000259|Pfam:PF00324"
FT REGION 19..50
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 32..50
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 572 AA; 63453 MW; 3CA44BADDC07D545 CRC64;
MEIGPSDLKE KSVIQDIDTI IDGNDSDSHN SNTGELGRRK RKTSVSSTQY EDLATEKDEL
LEHHDVKRSL KQRHIGMIAL GGTIGTGLFI GIATPLANAG PVGALVAYLF MGTVVFSVTQ
SLGEMATFIP VTSSFSVFAQ RFLSPALGAA NGYMYFLSWC FTFALELSVV GQIIQFWTFK
VPLAAWISIF WVLLTAFNMF PVKFYGEFEF WIASIKVLAL MGFLIYSLCI VCGAGKTGPI
GFRYWRNPGA MGPGIISSNT GEARFLGWVS SLINAAFTYQ GTELVGITAG EAANPRKAVP
RAIRKVLIRI LLFYIGSLFF IGLTVPYNDP KLTSTDSYVS SSPFIITIQN AGTRVLPHIF
NAVILTTIIS AGNSNVYVGS RILFSMAKNG LAPKFLAKTT LQGVPYLSVL AISAFGSLSY
MELSTGGAKA FNWLLNITGV AGFFAWLLIS CSHVRFMQAL KHRGISRDDL PYKALWMPWL
AYYAIFFMVV IILIQGFTSF APHFSGRDFV AAYISVGLFL VFWGFFQIYF RCRIIWKLED
VDIDTDRREI ESVVWEDDAP KTLWDKFWDF VA
//
