ID Q6FQ57_CANGA Unreviewed; 461 AA.
AC Q6FQ57;
DT 19-JUL-2004, integrated into UniProtKB/TrEMBL.
DT 19-JUL-2004, sequence version 1.
DT 27-MAR-2024, entry version 114.
DE RecName: Full=Arginosuccinase {ECO:0000256|ARBA:ARBA00032749};
GN OrderedLocusNames=CAGL0I08987g {ECO:0000313|CGD:CAL0132322,
GN ECO:0000313|EMBL:CAG60574.1};
OS Candida glabrata (strain ATCC 2001 / BCRC 20586 / JCM 3761 / NBRC 0622 /
OS NRRL Y-65 / CBS 138) (Yeast) (Nakaseomyces glabratus).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Saccharomycetaceae; Nakaseomyces.
OX NCBI_TaxID=284593 {ECO:0000313|EMBL:CAG60574.1, ECO:0000313|Proteomes:UP000002428};
RN [1] {ECO:0000313|EMBL:CAG60574.1, ECO:0000313|Proteomes:UP000002428}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65
RC {ECO:0000313|Proteomes:UP000002428};
RX PubMed=15229592; DOI=10.1038/nature02579;
RG Genolevures;
RA Dujon B., Sherman D., Fischer G., Durrens P., Casaregola S., Lafontaine I.,
RA de Montigny J., Marck C., Neuveglise C., Talla E., Goffard N., Frangeul L.,
RA Aigle M., Anthouard V., Babour A., Barbe V., Barnay S., Blanchin S.,
RA Beckerich J.M., Beyne E., Bleykasten C., Boisrame A., Boyer J.,
RA Cattolico L., Confanioleri F., de Daruvar A., Despons L., Fabre E.,
RA Fairhead C., Ferry-Dumazet H., Groppi A., Hantraye F., Hennequin C.,
RA Jauniaux N., Joyet P., Kachouri R., Kerrest A., Koszul R., Lemaire M.,
RA Lesur I., Ma L., Muller H., Nicaud J.M., Nikolski M., Oztas S.,
RA Ozier-Kalogeropoulos O., Pellenz S., Potier S., Richard G.F., Straub M.L.,
RA Suleau A., Swennene D., Tekaia F., Wesolowski-Louvel M., Westhof E.,
RA Wirth B., Zeniou-Meyer M., Zivanovic I., Bolotin-Fukuhara M., Thierry A.,
RA Bouchier C., Caudron B., Scarpelli C., Gaillardin C., Weissenbach J.,
RA Wincker P., Souciet J.L.;
RT "Genome evolution in yeasts.";
RL Nature 430:35-44(2004).
CC -!- SIMILARITY: Belongs to the lyase 1 family. Argininosuccinate lyase
CC subfamily. {ECO:0000256|ARBA:ARBA00010755}.
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DR EMBL; CR380955; CAG60574.1; -; Genomic_DNA.
DR RefSeq; XP_447637.1; XM_447637.1.
DR AlphaFoldDB; Q6FQ57; -.
DR STRING; 284593.Q6FQ57; -.
DR EnsemblFungi; CAGL0I08987g-T; CAGL0I08987g-T-p1; CAGL0I08987g.
DR GeneID; 2889017; -.
DR KEGG; cgr:CAGL0I08987g; -.
DR CGD; CAL0132322; CAGL0I08987g.
DR VEuPathDB; FungiDB:CAGL0I08987g; -.
DR eggNOG; KOG1316; Eukaryota.
DR HOGENOM; CLU_027272_2_1_1; -.
DR InParanoid; Q6FQ57; -.
DR OMA; DFAIEFC; -.
DR UniPathway; UPA00068; -.
DR Proteomes; UP000002428; Chromosome I.
DR GO; GO:0005829; C:cytosol; IEA:EnsemblFungi.
DR GO; GO:0004056; F:argininosuccinate lyase activity; IEA:EnsemblFungi.
DR GO; GO:0042450; P:arginine biosynthetic process via ornithine; IEA:EnsemblFungi.
DR CDD; cd01359; Argininosuccinate_lyase; 1.
DR Gene3D; 1.10.40.30; Fumarase/aspartase (C-terminal domain); 1.
DR Gene3D; 1.20.200.10; Fumarase/aspartase (Central domain); 1.
DR Gene3D; 1.10.275.10; Fumarase/aspartase (N-terminal domain); 1.
DR HAMAP; MF_00006; Arg_succ_lyase; 1.
DR InterPro; IPR029419; Arg_succ_lyase_C.
DR InterPro; IPR009049; Argininosuccinate_lyase.
DR InterPro; IPR024083; Fumarase/histidase_N.
DR InterPro; IPR020557; Fumarate_lyase_CS.
DR InterPro; IPR000362; Fumarate_lyase_fam.
DR InterPro; IPR022761; Fumarate_lyase_N.
DR InterPro; IPR008948; L-Aspartase-like.
DR NCBIfam; TIGR00838; argH; 1.
DR PANTHER; PTHR43814; ARGININOSUCCINATE LYASE; 1.
DR PANTHER; PTHR43814:SF1; ARGININOSUCCINATE LYASE; 1.
DR Pfam; PF14698; ASL_C2; 1.
DR Pfam; PF00206; Lyase_1; 1.
DR PRINTS; PR00145; ARGSUCLYASE.
DR PRINTS; PR00149; FUMRATELYASE.
DR SUPFAM; SSF48557; L-aspartase-like; 1.
DR PROSITE; PS00163; FUMARATE_LYASES; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000002428}.
FT DOMAIN 12..308
FT /note="Fumarate lyase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00206"
FT DOMAIN 371..439
FT /note="Argininosuccinate lyase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF14698"
SQ SEQUENCE 461 AA; 51875 MW; A20A1F7C1ED1A03B CRC64;
MSGQAKTKLW GGRFTGQTDP LMQLYNASLP YDYRMYKADL EGTKVYTAGL TKLGLITESE
LAKIHSGLKD IENEWDEGKF VRHESDEDIH TANERRLGEL IGRDIAGKVH TGRSRNDQVV
TDMRIYCREI LNEKIFPAMK SLINVLVNRA EKEIDILMPG YTHLQRAQPI RWAHWLSSYA
TYFTEDLKRL EQIAERLNKS PLGSGALAGH PYGIDRQFLA EGLGFNGVIG NSLVAVSDRD
FVVELMFWAT LFMNHVSRFS EDLIIYSTAE FGFIKLSDAY STGSSLMPQK KNADSLELLR
GKSGRVFGEL SGFLMSLKGI PSTYDKDMQE DKEPLFDCLT TVEHSILIAD GVISTLTVNK
EKMENALTMD MLATDLADYL VRKGVPFRET HSISGQCVAL AEKENLSGID KLSLEQFKNI
DPRFEQDLYE TFNFEMSVER RDAIGGTAKS AVLAQLKSLK L
//
