ID Q6FQP3_CANGA Unreviewed; 672 AA.
AC Q6FQP3;
DT 19-JUL-2004, integrated into UniProtKB/TrEMBL.
DT 19-JUL-2004, sequence version 1.
DT 27-MAR-2024, entry version 98.
DE SubName: Full=Candida glabrata strain CBS138 chromosome I complete sequence {ECO:0000313|EMBL:CAG60388.1};
GN OrderedLocusNames=CAGL0I04642g {ECO:0000313|CGD:CAL0132310,
GN ECO:0000313|EMBL:CAG60388.1};
OS Candida glabrata (strain ATCC 2001 / BCRC 20586 / JCM 3761 / NBRC 0622 /
OS NRRL Y-65 / CBS 138) (Yeast) (Nakaseomyces glabratus).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Saccharomycetaceae; Nakaseomyces.
OX NCBI_TaxID=284593 {ECO:0000313|EMBL:CAG60388.1, ECO:0000313|Proteomes:UP000002428};
RN [1] {ECO:0000313|EMBL:CAG60388.1, ECO:0000313|Proteomes:UP000002428}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65
RC {ECO:0000313|Proteomes:UP000002428};
RX PubMed=15229592; DOI=10.1038/nature02579;
RG Genolevures;
RA Dujon B., Sherman D., Fischer G., Durrens P., Casaregola S., Lafontaine I.,
RA de Montigny J., Marck C., Neuveglise C., Talla E., Goffard N., Frangeul L.,
RA Aigle M., Anthouard V., Babour A., Barbe V., Barnay S., Blanchin S.,
RA Beckerich J.M., Beyne E., Bleykasten C., Boisrame A., Boyer J.,
RA Cattolico L., Confanioleri F., de Daruvar A., Despons L., Fabre E.,
RA Fairhead C., Ferry-Dumazet H., Groppi A., Hantraye F., Hennequin C.,
RA Jauniaux N., Joyet P., Kachouri R., Kerrest A., Koszul R., Lemaire M.,
RA Lesur I., Ma L., Muller H., Nicaud J.M., Nikolski M., Oztas S.,
RA Ozier-Kalogeropoulos O., Pellenz S., Potier S., Richard G.F., Straub M.L.,
RA Suleau A., Swennene D., Tekaia F., Wesolowski-Louvel M., Westhof E.,
RA Wirth B., Zeniou-Meyer M., Zivanovic I., Bolotin-Fukuhara M., Thierry A.,
RA Bouchier C., Caudron B., Scarpelli C., Gaillardin C., Weissenbach J.,
RA Wincker P., Souciet J.L.;
RT "Genome evolution in yeasts.";
RL Nature 430:35-44(2004).
CC -!- SIMILARITY: Belongs to the ATP-dependent AMP-binding enzyme family.
CC {ECO:0000256|ARBA:ARBA00006432}.
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DR EMBL; CR380955; CAG60388.1; -; Genomic_DNA.
DR RefSeq; XP_447451.1; XM_447451.1.
DR AlphaFoldDB; Q6FQP3; -.
DR STRING; 284593.Q6FQP3; -.
DR EnsemblFungi; CAGL0I04642g-T; CAGL0I04642g-T-p1; CAGL0I04642g.
DR GeneID; 2889035; -.
DR KEGG; cgr:CAGL0I04642g; -.
DR CGD; CAL0132310; CAGL0I04642g.
DR VEuPathDB; FungiDB:CAGL0I04642g; -.
DR eggNOG; KOG1179; Eukaryota.
DR HOGENOM; CLU_000022_46_3_1; -.
DR InParanoid; Q6FQP3; -.
DR OMA; VWRQFLD; -.
DR Proteomes; UP000002428; Chromosome I.
DR GO; GO:0009898; C:cytoplasmic side of plasma membrane; IEA:EnsemblFungi.
DR GO; GO:0005783; C:endoplasmic reticulum; IEA:EnsemblFungi.
DR GO; GO:0005811; C:lipid droplet; IEA:EnsemblFungi.
DR GO; GO:0005777; C:peroxisome; IEA:EnsemblFungi.
DR GO; GO:0005324; F:long-chain fatty acid transporter activity; IEA:EnsemblFungi.
DR GO; GO:0031957; F:very long-chain fatty acid-CoA ligase activity; IEA:EnsemblFungi.
DR GO; GO:0044539; P:long-chain fatty acid import into cell; IEA:EnsemblFungi.
DR GO; GO:0006515; P:protein quality control for misfolded or incompletely synthesized proteins; IEA:EnsemblFungi.
DR GO; GO:0000038; P:very long-chain fatty acid metabolic process; IEA:EnsemblFungi.
DR Gene3D; 3.30.300.30; -; 1.
DR Gene3D; 3.40.50.12780; N-terminal domain of ligase-like; 1.
DR InterPro; IPR045851; AMP-bd_C_sf.
DR InterPro; IPR020845; AMP-binding_CS.
DR InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR InterPro; IPR042099; ANL_N_sf.
DR PANTHER; PTHR43107:SF15; FATTY ACID TRANSPORT PROTEIN 3, ISOFORM A; 1.
DR PANTHER; PTHR43107; LONG-CHAIN FATTY ACID TRANSPORT PROTEIN; 1.
DR Pfam; PF00501; AMP-binding; 1.
DR SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 1.
DR PROSITE; PS00455; AMP_BINDING; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000002428};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 7..30
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 83..412
FT /note="AMP-dependent synthetase/ligase"
FT /evidence="ECO:0000259|Pfam:PF00501"
SQ SEQUENCE 672 AA; 77847 MW; EE59772CC4534C5E CRC64;
MPAPFKIIIF LIGRIFWVLF KLVKIILYPI KELLSWSLGD WFNRLDAENH IREDIYIIPY
FFKAVFQYIW SVRKHRFQCW YQFEEQVRTN GHRPLISYPK PLAEKGEYEL QTYSYKETYD
IVLRLSYVMK NSYKVNAGDY IGIDCTNKPL FMFLWLASWN LGAIPAFLNY NTIGSPLVHS
LKISNISKVF IDPDASKPIK QTEEEILNAI PGIQLNYLQE QELMAILNDV NSPQFLQDPI
IRSPEGLTDF KPAMLIYTSG TTGLPKSAIM SWRKAHVGCQ LFGHVLHMDN TSTVFTAMPL
FHSTAALLGA CAILSKGGCL AISNKFSATN FWKQVYLTQA THVQYVGEIC RYLLHSPESK
YEHMHTAKIA YGNGLRPDIW QDFRKRFNLE VIGEFYAATE APFATTTFQR GDFGVGACRS
YGTIINWFLQ YQQTLVKMDP NDDSIIYRNS KGLCEVPDVG EPGEMLMRIF FPRKPETSFQ
GYLGNEKATK SKVLRDVFRK GDAWYRCGDL LKADKYGQWY FLDRMGDTFR WKSENVSTME
VEDQLTTASK NEITQVVVVG IKVPKYEGRA GFAVLKLKNH DYDSSEKIKL LNNWLSTLNK
TLPKYALPLF VKFVREIRMT DNHKISKKDY RDQKLPHGLD GKDEIFWLKN YNEYKLLTNE
DWKDIENNVA KL
//
