ID Q6FUL8_CANGA Unreviewed; 614 AA.
AC Q6FUL8;
DT 19-JUL-2004, integrated into UniProtKB/TrEMBL.
DT 19-JUL-2004, sequence version 1.
DT 27-MAR-2024, entry version 92.
DE SubName: Full=Candida glabrata strain CBS138 chromosome F complete sequence {ECO:0000313|EMBL:CAG59000.1};
GN OrderedLocusNames=CAGL0F02453g {ECO:0000313|CGD:CAL0131414,
GN ECO:0000313|EMBL:CAG59000.1};
OS Candida glabrata (strain ATCC 2001 / BCRC 20586 / JCM 3761 / NBRC 0622 /
OS NRRL Y-65 / CBS 138) (Yeast) (Nakaseomyces glabratus).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Saccharomycetaceae; Nakaseomyces.
OX NCBI_TaxID=284593 {ECO:0000313|EMBL:CAG59000.1, ECO:0000313|Proteomes:UP000002428};
RN [1] {ECO:0000313|EMBL:CAG59000.1, ECO:0000313|Proteomes:UP000002428}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65
RC {ECO:0000313|Proteomes:UP000002428};
RX PubMed=15229592; DOI=10.1038/nature02579;
RG Genolevures;
RA Dujon B., Sherman D., Fischer G., Durrens P., Casaregola S., Lafontaine I.,
RA de Montigny J., Marck C., Neuveglise C., Talla E., Goffard N., Frangeul L.,
RA Aigle M., Anthouard V., Babour A., Barbe V., Barnay S., Blanchin S.,
RA Beckerich J.M., Beyne E., Bleykasten C., Boisrame A., Boyer J.,
RA Cattolico L., Confanioleri F., de Daruvar A., Despons L., Fabre E.,
RA Fairhead C., Ferry-Dumazet H., Groppi A., Hantraye F., Hennequin C.,
RA Jauniaux N., Joyet P., Kachouri R., Kerrest A., Koszul R., Lemaire M.,
RA Lesur I., Ma L., Muller H., Nicaud J.M., Nikolski M., Oztas S.,
RA Ozier-Kalogeropoulos O., Pellenz S., Potier S., Richard G.F., Straub M.L.,
RA Suleau A., Swennene D., Tekaia F., Wesolowski-Louvel M., Westhof E.,
RA Wirth B., Zeniou-Meyer M., Zivanovic I., Bolotin-Fukuhara M., Thierry A.,
RA Bouchier C., Caudron B., Scarpelli C., Gaillardin C., Weissenbach J.,
RA Wincker P., Souciet J.L.;
RT "Genome evolution in yeasts.";
RL Nature 430:35-44(2004).
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DR EMBL; CR380952; CAG59000.1; -; Genomic_DNA.
DR RefSeq; XP_446076.1; XM_446076.1.
DR AlphaFoldDB; Q6FUL8; -.
DR STRING; 284593.Q6FUL8; -.
DR EnsemblFungi; CAGL0F02453g-T; CAGL0F02453g-T-p1; CAGL0F02453g.
DR GeneID; 2887844; -.
DR KEGG; cgr:CAGL0F02453g; -.
DR CGD; CAL0131414; CAGL0F02453g.
DR VEuPathDB; FungiDB:CAGL0F02453g; -.
DR eggNOG; KOG4406; Eukaryota.
DR HOGENOM; CLU_027718_0_0_1; -.
DR InParanoid; Q6FUL8; -.
DR OMA; KKISWVY; -.
DR Proteomes; UP000002428; Chromosome F.
DR GO; GO:0005096; F:GTPase activator activity; IEA:UniProt.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR CDD; cd00159; RhoGAP; 1.
DR Gene3D; 3.40.525.10; CRAL-TRIO lipid binding domain; 1.
DR Gene3D; 1.10.555.10; Rho GTPase activation protein; 1.
DR InterPro; IPR001251; CRAL-TRIO_dom.
DR InterPro; IPR036865; CRAL-TRIO_dom_sf.
DR InterPro; IPR008936; Rho_GTPase_activation_prot.
DR InterPro; IPR000198; RhoGAP_dom.
DR Pfam; PF13716; CRAL_TRIO_2; 1.
DR Pfam; PF00620; RhoGAP; 1.
DR SMART; SM00324; RhoGAP; 1.
DR SUPFAM; SSF48350; GTPase activation domain, GAP; 1.
DR PROSITE; PS50238; RHOGAP; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000002428}.
FT DOMAIN 187..372
FT /note="Rho-GAP"
FT /evidence="ECO:0000259|PROSITE:PS50238"
FT REGION 422..522
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 459..506
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 507..521
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 614 AA; 70319 MW; 83289984172B33F0 CRC64;
MEEVINLNNI FYKSYSVDPN TGHSIYVFDS TYLPSAAELG VNDKNDYDEM ITELMDMLVK
KLPQAPFSLV IFSSGFSAKK ISWVYGVKMY SKLPKLFKKY LQETYIVHES FFVRTVYQVL
SNAMNFKFLT NNKSEQNGTV EDESRNGNAI RHVSTLSELA CMIDITRLRI SLNVYLHDSE
VTGEYFLSLP DYYTEKLSPT SKRQYRQIIF DKIFNRLKYD ALTNELVFQR PGSYKKVNIL
LSIIERNNYI DLSQWDIYSL ASIFTNFLKN KSKPLIPIDL IELPIHDNFE YTFQVFKEIV
RYNNYYDILC AIFPLFISIL NAGDITRHDS RSLSRALTPT LCKEKVSMMS SDRLAIGNKY
IRNLFEHFHD IIKVLETNEK RNEKISKSDI AELANLTINT HININSRSSS GSSDLLLDIN
SDRSGSVSSS PKIPPKLPPR RNASSELKLA KEESSIQRPV RAISLSHTNS EDESNTSLPS
VNSTFSKASS STDSTNIEQE NKNTDINNDN TNDKDSPVKT ERNNNDIQNM ITDGFADVDV
SQVVLKKDKI QEFDKELQKK KKLAGEENTV KTIKFSTESY SDIKTNKVSK LAALYEERLM
GLQVMNEIRH QNSV
//
