ID Q6FUN1_CANGA Unreviewed; 1223 AA.
AC Q6FUN1;
DT 19-JUL-2004, integrated into UniProtKB/TrEMBL.
DT 19-JUL-2004, sequence version 1.
DT 27-MAR-2024, entry version 132.
DE RecName: Full=Structural maintenance of chromosomes protein {ECO:0000256|PIRNR:PIRNR005719};
GN OrderedLocusNames=CAGL0F02079g {ECO:0000313|CGD:CAL0131032,
GN ECO:0000313|EMBL:CAG58987.1};
OS Candida glabrata (strain ATCC 2001 / BCRC 20586 / JCM 3761 / NBRC 0622 /
OS NRRL Y-65 / CBS 138) (Yeast) (Nakaseomyces glabratus).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Saccharomycetaceae; Nakaseomyces.
OX NCBI_TaxID=284593 {ECO:0000313|EMBL:CAG58987.1, ECO:0000313|Proteomes:UP000002428};
RN [1] {ECO:0000313|EMBL:CAG58987.1, ECO:0000313|Proteomes:UP000002428}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65
RC {ECO:0000313|Proteomes:UP000002428};
RX PubMed=15229592; DOI=10.1038/nature02579;
RG Genolevures;
RA Dujon B., Sherman D., Fischer G., Durrens P., Casaregola S., Lafontaine I.,
RA de Montigny J., Marck C., Neuveglise C., Talla E., Goffard N., Frangeul L.,
RA Aigle M., Anthouard V., Babour A., Barbe V., Barnay S., Blanchin S.,
RA Beckerich J.M., Beyne E., Bleykasten C., Boisrame A., Boyer J.,
RA Cattolico L., Confanioleri F., de Daruvar A., Despons L., Fabre E.,
RA Fairhead C., Ferry-Dumazet H., Groppi A., Hantraye F., Hennequin C.,
RA Jauniaux N., Joyet P., Kachouri R., Kerrest A., Koszul R., Lemaire M.,
RA Lesur I., Ma L., Muller H., Nicaud J.M., Nikolski M., Oztas S.,
RA Ozier-Kalogeropoulos O., Pellenz S., Potier S., Richard G.F., Straub M.L.,
RA Suleau A., Swennene D., Tekaia F., Wesolowski-Louvel M., Westhof E.,
RA Wirth B., Zeniou-Meyer M., Zivanovic I., Bolotin-Fukuhara M., Thierry A.,
RA Bouchier C., Caudron B., Scarpelli C., Gaillardin C., Weissenbach J.,
RA Wincker P., Souciet J.L.;
RT "Genome evolution in yeasts.";
RL Nature 430:35-44(2004).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC ECO:0000256|PIRNR:PIRNR005719}.
CC -!- SIMILARITY: Belongs to the SMC family. SMC1 subfamily.
CC {ECO:0000256|ARBA:ARBA00005597}.
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DR EMBL; CR380952; CAG58987.1; -; Genomic_DNA.
DR RefSeq; XP_446063.1; XM_446063.1.
DR AlphaFoldDB; Q6FUN1; -.
DR STRING; 284593.Q6FUN1; -.
DR EnsemblFungi; CAGL0F02079g-T; CAGL0F02079g-T-p1; CAGL0F02079g.
DR GeneID; 2887737; -.
DR KEGG; cgr:CAGL0F02079g; -.
DR CGD; CAL0131032; CAGL0F02079g.
DR VEuPathDB; FungiDB:CAGL0F02079g; -.
DR eggNOG; KOG0018; Eukaryota.
DR HOGENOM; CLU_001042_0_1_1; -.
DR InParanoid; Q6FUN1; -.
DR OMA; SYIRDHT; -.
DR Proteomes; UP000002428; Chromosome F.
DR GO; GO:0030892; C:mitotic cohesin complex; IEA:EnsemblFungi.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0003690; F:double-stranded DNA binding; IEA:EnsemblFungi.
DR GO; GO:0042802; F:identical protein binding; IEA:EnsemblFungi.
DR GO; GO:0003680; F:minor groove of adenine-thymine-rich DNA binding; IEA:EnsemblFungi.
DR GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR GO; GO:0006302; P:double-strand break repair; IEA:EnsemblFungi.
DR GO; GO:0007064; P:mitotic sister chromatid cohesion; IEA:EnsemblFungi.
DR GO; GO:0000070; P:mitotic sister chromatid segregation; IEA:EnsemblFungi.
DR CDD; cd03275; ABC_SMC1_euk; 2.
DR Gene3D; 1.10.287.1490; -; 1.
DR Gene3D; 1.20.1060.20; -; 1.
DR Gene3D; 3.30.70.1620; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR003395; RecF/RecN/SMC_N.
DR InterPro; IPR024704; SMC.
DR InterPro; IPR028468; Smc1_ABC.
DR InterPro; IPR010935; SMC_hinge.
DR InterPro; IPR036277; SMC_hinge_sf.
DR PANTHER; PTHR18937:SF12; STRUCTURAL MAINTENANCE OF CHROMOSOMES PROTEIN; 1.
DR PANTHER; PTHR18937; STRUCTURAL MAINTENANCE OF CHROMOSOMES SMC FAMILY MEMBER; 1.
DR Pfam; PF06470; SMC_hinge; 1.
DR Pfam; PF02463; SMC_N; 1.
DR PIRSF; PIRSF005719; SMC; 1.
DR SMART; SM00968; SMC_hinge; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF75553; Smc hinge domain; 1.
PE 3: Inferred from homology;
KW Cell cycle {ECO:0000256|ARBA:ARBA00022776};
KW Cell division {ECO:0000256|ARBA:ARBA00022618};
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Mitosis {ECO:0000256|ARBA:ARBA00022776};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|PIRNR:PIRNR005719};
KW Reference proteome {ECO:0000313|Proteomes:UP000002428}.
FT DOMAIN 525..640
FT /note="SMC hinge"
FT /evidence="ECO:0000259|SMART:SM00968"
FT COILED 251..365
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 405..443
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 729..785
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 809..934
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 1223 AA; 140433 MW; F40BDB3F398BDC8E CRC64;
MGRLVGLELY NFKSYKGTVN VDFGDSNFTS IIGPNGSGKS NLMDAISFVL GIRSSSLRSS
ALKDLIYRDI ISRENTPTGA DNDENGNRTA YVKAFYEYDG KVVELMRLIS RLGDTSYKLD
GNTVTYKEYS QFLESQNILI KAKNFLVFQG DVEQIASQSP LGLTKLIEEV SGSMQYKKEY
EELKDQYDKI CQASTESIKK RRRIHAELKT YKEGMSRDEE YRKYVQKKKR VQTNLSLWQL
YHMEDERYQC LQKLEESQND VDVIREKLEA EEKNLEVFKK ALSKEAVLLT KKKNHIRSIS
KEKEKAESDL KVVKIPQNAS INRLKNLDKR VDSLQKDLER EEANLEKYKH QLKVVTDSKN
AFEQEILSKS KNNNKFTLSE DDLKLYDELK GEYLNNGGIE IEDTLNLLDN KKEEITADLK
IINDKVEISK QRIEDELVTK KEEQDAKIRD STLLLNEKND LHSHKLDELR KTQKDIEYWN
NKEFDLNHKL RDTLVKLDDL NATQRESNKE RKLRENVAML KRFFPGVRGL VHELCKPKRD
KYKLAVSTVL GKNFDSVIVD SLSVAQECIS FLKKQRAGVI SFIPLDTIDA ATPRMPVPES
ETYTLAINTV EYKDDLVRAM YYVCSDTIIC DNLDIARDLK WNKNANVKIV TLDGALINKT
GLMTGGITSD SANRWDKDEY QSLLDLKDKL IVDVEEAANK SRQSTLIARE LEISLSSLTS
EISYIRTQIT QTKRAVEETE TEINHHNNLI DREFIPQVKD LENKISGLED EIRDWNTKRE
ALQEKCFARL TEKVGFTMKD YESHTGEMIR KQTKELQILQ KQILNLENKV EFETGRCNAT
KDRLQNVQET KNSVQHELNE LVDQEKSIKL SIETLEGELD GKNEELKSIK AAFDSKQKDA
SATEDIISEY NNRLASIESD RNEIKDDITR LDLEKMSILK NCQVSGIIVP VVSEVGLEEL
PASKVDDEAI EIAKKIEIDF SKLPRKYKEA TSAAVKQDLN NQIRDIDDVL EELQPNARAV
ERFDDAKSRF DEVDKETEGL KTEERKVFDE FLKVKQKRKE LFENAFEKIN EHLDAIYSEL
TRNVNSTSIL GGGSASMTIE DEDEPFNAGI RYHATPPMKR FKDMEYLSGG EKTVAALALL
FAINSYNPSP FFILDEVDAA LDISNVQRIA AYIRRHGNPD LQFIVISLKN TMFEKSDALV
GVFRQQQENS SKIVTLDLNQ YAT
//
