ID Q6GNU7_XENLA Unreviewed; 534 AA.
AC Q6GNU7;
DT 19-JUL-2004, integrated into UniProtKB/TrEMBL.
DT 19-JUL-2004, sequence version 1.
DT 27-MAR-2024, entry version 117.
DE SubName: Full=DnaJ heat shock protein family (Hsp40) member C1 S homeolog precursor {ECO:0000313|RefSeq:NP_001085833.1};
DE SubName: Full=MGC80867 protein {ECO:0000313|EMBL:AAH73404.1};
GN Name=dnajc1.S {ECO:0000313|RefSeq:NP_001085833.1,
GN ECO:0000313|Xenbase:XB-GENE-950436};
GN Synonyms=dnajc1 {ECO:0000313|RefSeq:NP_001085833.1,
GN ECO:0000313|Xenbase:XB-GENE-950436}, MGC80867
GN {ECO:0000313|EMBL:AAH73404.1};
OS Xenopus laevis (African clawed frog).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus.
OX NCBI_TaxID=8355 {ECO:0000313|EMBL:AAH73404.1};
RN [1] {ECO:0000313|RefSeq:NP_001085833.1}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=12454917; DOI=10.1002/dvdy.10174;
RA Klein S.L., Strausberg R.L., Wagner L., Pontius J., Clifton S.W.,
RA Richardson P.;
RT "Genetic and genomic tools for Xenopus research: The NIH Xenopus
RT initiative.";
RL Dev. Dyn. 225:384-391(2002).
RN [2] {ECO:0000313|EMBL:AAH73404.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Embryo {ECO:0000313|EMBL:AAH73404.1};
RG NIH - Xenopus Gene Collection (XGC) project;
RL Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|RefSeq:NP_001085833.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; BC073404; AAH73404.1; -; mRNA.
DR RefSeq; NP_001085833.1; NM_001092364.1.
DR STRING; 8355.Q6GNU7; -.
DR PaxDb; 8355-Q6GNU7; -.
DR DNASU; 444260; -.
DR GeneID; 444260; -.
DR KEGG; xla:444260; -.
DR AGR; Xenbase:XB-GENE-950436; -.
DR CTD; 444260; -.
DR Xenbase; XB-GENE-950436; dnajc1.S.
DR OMA; LLMCGTA; -.
DR OrthoDB; 618716at2759; -.
DR Proteomes; UP000186698; Chromosome 6S.
DR Bgee; 444260; Expressed in liver and 19 other cell types or tissues.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR CDD; cd06257; DnaJ; 1.
DR CDD; cd00167; SANT; 2.
DR Gene3D; 1.10.287.110; DnaJ domain; 1.
DR Gene3D; 1.10.10.60; Homeodomain-like; 2.
DR InterPro; IPR001623; DnaJ_domain.
DR InterPro; IPR018253; DnaJ_domain_CS.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR036869; J_dom_sf.
DR InterPro; IPR001005; SANT/Myb.
DR PANTHER; PTHR44653; DNAJ HOMOLOG SUBFAMILY C MEMBER 1; 1.
DR PANTHER; PTHR44653:SF2; DNAJ HOMOLOG SUBFAMILY C MEMBER 1; 1.
DR Pfam; PF00226; DnaJ; 1.
DR Pfam; PF00249; Myb_DNA-binding; 1.
DR PRINTS; PR00625; JDOMAIN.
DR SMART; SM00271; DnaJ; 1.
DR SMART; SM00717; SANT; 2.
DR SUPFAM; SSF46565; Chaperone J-domain; 1.
DR SUPFAM; SSF46689; Homeodomain-like; 2.
DR PROSITE; PS00636; DNAJ_1; 1.
DR PROSITE; PS50076; DNAJ_2; 1.
DR PROSITE; PS50090; MYB_LIKE; 1.
PE 2: Evidence at transcript level;
KW Coiled coil {ECO:0000256|SAM:Coils}; Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000186698};
KW Signal {ECO:0000256|SAM:SignalP, ECO:0000313|RefSeq:NP_001085833.1};
KW Stress response {ECO:0000313|RefSeq:NP_001085833.1};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..26
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 27..534
FT /evidence="ECO:0000256|SAM:SignalP,
FT ECO:0000313|RefSeq:NP_001085833.1"
FT /id="PRO_5033206813"
FT TRANSMEM 133..154
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 44..108
FT /note="J"
FT /evidence="ECO:0000259|PROSITE:PS50076"
FT DOMAIN 469..523
FT /note="Myb-like"
FT /evidence="ECO:0000259|PROSITE:PS50090"
FT REGION 391..479
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 228..256
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 432..451
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 459..473
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 534 AA; 61559 MW; 363885F0829E86E9 CRC64;
MWGCGARLLL PLLFLGCCTQ LHTVGAWDSG DLELFDLVEE IQQNFYEFLG VEQDASSADI
RKAYRKLSLT LHPDKNKEEN AETQFRQLVA IYEVLKDEER RQRYDDILVN GLPDWRQPVF
YYRRVRKMSN AELALLLFII FTVGHYAVVW SIYLEKQLDE LLSKKKKEKK KKAGAKALDE
IKFGQMEKNE RVLEKPQWQD LLPFKLGIWF YLTVRSLPQL YQDAKQYYIE YQEKKLKEKE
EAAELAELEL IQKEKKPKVK KAKSEFPVYS AATANVILPG YDQCASIEDI ESQMDDWLDC
RGRDQKKKAP EWTEEDLSQL TRNMTKFPGG TPGRWEKIAH ELGRSVTDVT TKAKQLKDAV
SCSSGTVRFS DLKCSVKASV NLSDSLITHR EEEELDSEEQ DLPAGQSEGH TTAARARRRK
GARGAAEAAS SSRGEVEEKV RGRRQRDFDT EQEAEELGDS DNDMRKKEQS RSSEDLWSQN
QQKLLELALQ QYPKGTGERW DKIAKCVPGK SKEDCICRYK LLVELVQKKK QAKS
//
