ID   Q6LPP0_PHOPR            Unreviewed;       572 AA.
AC   Q6LPP0;
DT   05-JUL-2004, integrated into UniProtKB/TrEMBL.
DT   05-JUL-2004, sequence version 1.
DT   27-MAR-2024, entry version 98.
DE   RecName: Full=Murein L,D-transpeptidase {ECO:0008006|Google:ProtNLM};
GN   Name=VP1916 {ECO:0000313|EMBL:CAG20736.1};
GN   OrderedLocusNames=PBPRA2351 {ECO:0000313|EMBL:CAG20736.1};
OS   Photobacterium profundum (strain SS9).
OC   Bacteria; Pseudomonadota; Gammaproteobacteria; Vibrionales; Vibrionaceae;
OC   Photobacterium.
OX   NCBI_TaxID=298386 {ECO:0000313|EMBL:CAG20736.1, ECO:0000313|Proteomes:UP000000593};
RN   [1] {ECO:0000313|Proteomes:UP000000593}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-1253 / SS9 {ECO:0000313|Proteomes:UP000000593};
RX   PubMed=15746425; DOI=10.1126/science.1103341;
RA   Vezzi A., Campanaro S., D'Angelo M., Simonato F., Vitulo N., Lauro F.M.,
RA   Cestaro A., Malacrida G., Simionati B., Cannata N., Romualdi C.,
RA   Bartlett D.H., Valle G.;
RT   "Life at depth: Photobacterium profundum genome sequence and expression
RT   analysis.";
RL   Science 307:1459-1461(2005).
CC   -!- PATHWAY: Cell wall biogenesis; peptidoglycan biosynthesis.
CC       {ECO:0000256|ARBA:ARBA00004752}.
CC   -!- SIMILARITY: Belongs to the YkuD family.
CC       {ECO:0000256|ARBA:ARBA00005992}.
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DR   EMBL; CR378670; CAG20736.1; -; Genomic_DNA.
DR   RefSeq; WP_011219024.1; NC_006370.1.
DR   AlphaFoldDB; Q6LPP0; -.
DR   STRING; 298386.PBPRA2351; -.
DR   KEGG; ppr:PBPRA2351; -.
DR   eggNOG; COG2989; Bacteria.
DR   HOGENOM; CLU_020360_3_0_6; -.
DR   UniPathway; UPA00219; -.
DR   Proteomes; UP000000593; Chromosome 1.
DR   GO; GO:0004180; F:carboxypeptidase activity; IEA:UniProt.
DR   GO; GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
DR   GO; GO:0009252; P:peptidoglycan biosynthetic process; IEA:UniProtKB-UniPathway.
DR   CDD; cd16913; YkuD_like; 1.
DR   Gene3D; 2.40.440.10; L,D-transpeptidase catalytic domain-like; 1.
DR   Gene3D; 1.10.101.10; PGBD-like superfamily/PGBD; 1.
DR   InterPro; IPR005490; LD_TPept_cat_dom.
DR   InterPro; IPR045380; LD_TPept_scaffold_dom.
DR   InterPro; IPR002477; Peptidoglycan-bd-like.
DR   InterPro; IPR036365; PGBD-like_sf.
DR   InterPro; IPR036366; PGBDSf.
DR   InterPro; IPR038063; Transpep_catalytic_dom.
DR   PANTHER; PTHR41533; L,D-TRANSPEPTIDASE HI_1667-RELATED; 1.
DR   PANTHER; PTHR41533:SF1; L,D-TRANSPEPTIDASE YCBB-RELATED; 1.
DR   Pfam; PF01471; PG_binding_1; 1.
DR   Pfam; PF20142; Scaffold; 1.
DR   Pfam; PF03734; YkuD; 1.
DR   SUPFAM; SSF141523; L,D-transpeptidase catalytic domain-like; 1.
DR   SUPFAM; SSF47090; PGBD-like; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000000593};
KW   Signal {ECO:0000256|SAM:SignalP};
KW   Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT   SIGNAL          1..23
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           24..572
FT                   /note="Murein L,D-transpeptidase"
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5004276999"
FT   DOMAIN          82..212
FT                   /note="L,D-transpeptidase scaffold"
FT                   /evidence="ECO:0000259|Pfam:PF20142"
FT   DOMAIN          282..305
FT                   /note="Peptidoglycan binding-like"
FT                   /evidence="ECO:0000259|Pfam:PF01471"
FT   DOMAIN          333..496
FT                   /note="L,D-transpeptidase catalytic"
FT                   /evidence="ECO:0000259|Pfam:PF03734"
SQ   SEQUENCE   572 AA;  65660 MW;  E219A3FB894C5BAC CRC64;
     MAMIRQSCIS LLLISIISIS VSANEPLLTP TPSLLSEQNI NTQQQFISEP VVSPETALQQ
     QKSLLWVKEV ADDLSSIQYI DKLAQLYASI AYTPIWQDAF AATELEEQLR IVALSRVSSD
     LSRRYSQLKH YKLANDWRQY DLLATDTLLA YMSYIENLPK FGRGWLFGTG IDVPLPLPTK
     IQTGRLLDAI DNNRMRYFVT SLKPVNDNYN KMILAMQTLE VSESEHWPGF YQQGIIRLGD
     RLKDPDSLIT ILERMGDITE YDADRMRTSQ LRSLTIPLSL GVKTFQKRHG LKVDGVIGPK
     TRYWLAITPK ERIRVLALNA QRVRLWPAEY NSVLIVNIPG YELNLWLDNK HVFDSKVIVG
     RPSRRTPLIS SRVNSVVFNP YWNVPKSIMR KDILPKARRD RSYLYRHNYA VIRSWNSSEQ
     IPIHTIHPSM LYAKTFPYRL RQKPGNKNAL GLYKFIIPND NSIYLHDTPA KSLFNKDDRA
     FSSGCVRVEN ADVLALILLN YSGVTDQRFY ELSGRKQTKT IGLRNKVKVH LIYQTAWVDD
     GGLVNFRDDV YLYDKVGGGS QSDQKYTSAY NH
//