ID Q6N5H3_RHOPA Unreviewed; 907 AA.
AC Q6N5H3;
DT 05-JUL-2004, integrated into UniProtKB/TrEMBL.
DT 05-JUL-2004, sequence version 1.
DT 27-MAR-2024, entry version 130.
DE RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN Name=kdpD {ECO:0000313|EMBL:CAE28442.1};
GN OrderedLocusNames=RPA3001 {ECO:0000313|EMBL:CAE28442.1};
OS Rhodopseudomonas palustris (strain ATCC BAA-98 / CGA009).
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Hyphomicrobiales;
OC Nitrobacteraceae; Rhodopseudomonas.
OX NCBI_TaxID=258594 {ECO:0000313|EMBL:CAE28442.1, ECO:0000313|Proteomes:UP000001426};
RN [1] {ECO:0000313|EMBL:CAE28442.1, ECO:0000313|Proteomes:UP000001426}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-98 / CGA009 {ECO:0000313|Proteomes:UP000001426};
RX PubMed=14704707; DOI=10.1038/nbt923;
RA Larimer F.W., Chain P., Hauser L., Lamerdin J., Malfatti S., Do L.,
RA Land M.L., Pelletier D.A., Beatty T.J., Lang A.S., Tabita F.R.,
RA Gibson J.L., Hanson T.E., Torres y Torres J., Peres C., Harrison F.H.,
RA Gibson J., Harwood C.S.;
RT "Complete genome sequence of the metabolically versatile photosynthetic
RT bacterium Rhodopseudomonas palustris.";
RL Nat. Biotechnol. 22:55-61(2004).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
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DR EMBL; BX572602; CAE28442.1; -; Genomic_DNA.
DR RefSeq; WP_011158549.1; NZ_CP116810.1.
DR AlphaFoldDB; Q6N5H3; -.
DR STRING; 258594.RPA3001; -.
DR GeneID; 66894086; -.
DR eggNOG; COG2205; Bacteria.
DR HOGENOM; CLU_000445_113_1_5; -.
DR PhylomeDB; Q6N5H3; -.
DR Proteomes; UP000001426; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR CDD; cd00075; HATPase; 1.
DR CDD; cd00082; HisKA; 1.
DR CDD; cd01987; USP_OKCHK; 1.
DR Gene3D; 1.10.287.130; -; 1.
DR Gene3D; 3.30.450.40; -; 1.
DR Gene3D; 1.20.120.620; Backbone structure of the membrane domain of e. Coli histidine kinase receptor kdpd; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR Gene3D; 3.40.50.620; HUPs; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR003018; GAF.
DR InterPro; IPR029016; GAF-like_dom_sf.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR003661; HisK_dim/P.
DR InterPro; IPR036097; HisK_dim/P_sf.
DR InterPro; IPR038318; KdpD_sf.
DR InterPro; IPR025201; KdpD_TM.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR014729; Rossmann-like_a/b/a_fold.
DR InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR InterPro; IPR003852; Sig_transdc_His_kinase_KdpD_N.
DR InterPro; IPR006016; UspA.
DR PANTHER; PTHR45569; SENSOR PROTEIN KDPD; 1.
DR PANTHER; PTHR45569:SF1; SENSOR PROTEIN KDPD; 1.
DR Pfam; PF13493; DUF4118; 1.
DR Pfam; PF13492; GAF_3; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF00512; HisKA; 1.
DR Pfam; PF02702; KdpD; 1.
DR Pfam; PF00582; Usp; 1.
DR PRINTS; PR00344; BCTRLSENSOR.
DR SMART; SM00387; HATPase_c; 1.
DR SMART; SM00388; HisKA; 1.
DR SUPFAM; SSF52402; Adenine nucleotide alpha hydrolases-like; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF55781; GAF domain-like; 1.
DR SUPFAM; SSF47384; Homodimeric domain of signal transducing histidine kinase; 1.
DR PROSITE; PS50109; HIS_KIN; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Kinase {ECO:0000256|ARBA:ARBA00022777, ECO:0000313|EMBL:CAE28442.1};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000001426};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius};
KW Two-component regulatory system {ECO:0000256|ARBA:ARBA00023012}.
FT TRANSMEM 409..428
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 440..473
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 485..504
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 681..898
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
SQ SEQUENCE 907 AA; 98424 MW; E70C8E1E65345546 CRC64;
MPDPRVEPPS RPSPDALLEQ ARRQEPGTGR LKVFLGAAPG VGKTYAMLQS AHARAKAGVD
VVIGYAETHG RAETEALLAG LETVPRRRIP YKGQVLEEMD LDAVLARRPQ LAIVDELAHS
NAPGSRHPKR YLDVLELLAN GIDVYTAVNI QHIESLNDVV AQITTVRVRE TVPDSAFERA
DAIELVDLTP DDLIQRLKEG KVYVPKQAER ALEHYFSPGN LTALRELALR RTAERVDEQL
LSHMQANAIP GPWAAGERVL VCVSHDQRSQ GLVRYTKRLA DRLRAPWTAI NIETRRSLSL
TEQQRDRLAD TLRLAEALGG EALAIPGGDR SLAHDILAFA RANNITQIVV GKAPRSFWYE
ALRGSTVHEL VRGSGNISIH VMTGTAVSIE ESQTGSLRPA EGTEPFNPWP YPMALVLVGI
GLGVAKLIEP FFSIENVDLV FLTAVVGVAV RYGLGPSLLA SVVASLCYNF FFLPPVYTFT
ITDPTNIVAF FFFMLIAILV SNLAGRVRAQ ATAAAQRVRT TESLYAFSRK LAGTAALDDV
LWATAYQIAL MLKVRVVLLL PEQGRIAVKA GYPPEDQLDP ADLAAANWAW ENDRVAGRGS
DTLPGAKRLF LPMRTGRGPI GVIGIDDDRA GALLTPDQRR LLDALTDQGA LAIERVHLVE
DMDRVKRDAE SDRLRQALLT SISHDLKTPL AAVLGAATTM RDLASHLSDA QRTELIGTIV
EESERLNRFI ANLLDMTKLE SGAVVPNSAA HDLGELVGAT LRRATSILAQ HTVKLDLGHD
LPLIEVDPVL FEQALFNLLD NAAKYAPAGS AIQLRAAQSG GQVELQVRDE GEGIPPAELE
TVFDKFYRVR KGDHIRPGTG LGLAIARGFI EAMGGRLSAG NRSDRSGAAM TIRLPIASRG
DALISAA
//
