ID Q6NFZ6_CORDI Unreviewed; 608 AA.
AC Q6NFZ6;
DT 05-JUL-2004, integrated into UniProtKB/TrEMBL.
DT 05-JUL-2004, sequence version 1.
DT 27-MAR-2024, entry version 91.
DE SubName: Full=Ectoine, glycine betaine and proline transport system membrane protein {ECO:0000313|EMBL:CAE50268.1};
GN Name=ectP {ECO:0000313|EMBL:CAE50268.1};
GN OrderedLocusNames=DIP1739 {ECO:0000313|EMBL:CAE50268.1};
OS Corynebacterium diphtheriae (strain ATCC 700971 / NCTC 13129 / Biotype
OS gravis).
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales;
OC Corynebacteriaceae; Corynebacterium.
OX NCBI_TaxID=257309 {ECO:0000313|EMBL:CAE50268.1, ECO:0000313|Proteomes:UP000002198};
RN [1] {ECO:0000313|EMBL:CAE50268.1, ECO:0000313|Proteomes:UP000002198}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 700971 / NCTC 13129 / Biotype gravis
RC {ECO:0000313|Proteomes:UP000002198};
RX PubMed=14602910; DOI=10.1093/nar/gkg874;
RA Cerdeno-Tarraga A.M., Efstratiou A., Dover L.G., Holden M.T.G., Pallen M.,
RA Bentley S.D., Besra G.S., Churcher C., James K.D., De Zoysa A.,
RA Chillingworth T., Cronin A., Dowd L., Feltwell T., Hamlin N., Holroyd S.,
RA Jagels K., Moule S., Quail M.A., Rabbinowitsch E., Rutherford K.,
RA Thomson N.R., Unwin L., Whitehead S., Barrell B.G.Parkhill.J.;
RT "The complete genome sequence and analysis of Corynebacterium diphtheriae
RT NCTC13129.";
RL Nucleic Acids Res. 31:6516-6523(2003).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the BCCT transporter (TC 2.A.15) family.
CC {ECO:0000256|ARBA:ARBA00005658}.
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DR EMBL; BX248359; CAE50268.1; -; Genomic_DNA.
DR RefSeq; WP_010935295.1; NC_002935.2.
DR AlphaFoldDB; Q6NFZ6; -.
DR STRING; 257309.DIP1739; -.
DR KEGG; cdi:DIP1739; -.
DR HOGENOM; CLU_010118_4_1_11; -.
DR Proteomes; UP000002198; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0071705; P:nitrogen compound transport; IEA:InterPro.
DR InterPro; IPR000060; BCCT_transptr.
DR NCBIfam; TIGR00842; bcct; 1.
DR PANTHER; PTHR30047:SF7; HIGH-AFFINITY CHOLINE TRANSPORT PROTEIN; 1.
DR PANTHER; PTHR30047; HIGH-AFFINITY CHOLINE TRANSPORT PROTEIN-RELATED; 1.
DR Pfam; PF02028; BCCT; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000002198};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 24..43
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 63..82
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 102..123
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 158..176
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 203..222
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 242..263
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 275..295
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 331..349
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 361..384
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 415..437
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 457..477
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 489..509
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 608 AA; 66460 MW; 52D330282883EF3B CRC64;
MSDPIVAEPV SAKRPFLGLK TDPFIFLSSL GFVILFVVAT ILLGEKASSA FTTIAQGLLK
NTGWLYVGGV SFMFIFLIAI FISRYGRLRL GDDDDEPEHG LIAWFCMLFA GGIGAVLMFW
GVAEPLNHSV NVPQQDAEPM SEQAITEAFA YTFYHFGIHM WAIVALPGLA LGYFIYKRKL
PPRVSSVFAP ILGSRIYSLP GKLIDALSII ATTFGIAVSV GLGVLQINSG LKRLWGVPEV
SWVQLAIILV ITVIACISVA SGLEKGIKLL SNINIGLAVL LMIFVLVTGP TLTLLRFTTE
AFGIYADWLP SLMFWTDSYG DNPGWQGKWT VFYWAWTICW SPYVGMFVAR ISRGRTVREY
IGGVLALPAI FSVIWFAIFG RAGIEIELNS PGKLTGPIVH DGDVPFALFG FFHEYPLSGL
VSALALLVVV IFFITSIDSA GMVNDMFSTG EEEVSPVGYR VLWVVAIGAV AGALLIISPN
SGIATLQEVV IIVAFPFFIT QFVMMYSLIK GMTDDSAAER RIQTRQWQKT DTAEKLEAHE
AMPAPGYDLE GNELPVVALA HDEDGNIVIP GNVVIEGDLG VVGDMVEEEE EPGFKIVEQT
RPKTQEDW
//
