ID Q6NHF6_CORDI Unreviewed; 579 AA.
AC Q6NHF6;
DT 05-JUL-2004, integrated into UniProtKB/TrEMBL.
DT 05-JUL-2004, sequence version 1.
DT 27-MAR-2024, entry version 114.
DE RecName: Full=DNA repair protein RecN {ECO:0000256|ARBA:ARBA00021315, ECO:0000256|PIRNR:PIRNR003128};
DE AltName: Full=Recombination protein N {ECO:0000256|ARBA:ARBA00033408, ECO:0000256|PIRNR:PIRNR003128};
GN Name=recN {ECO:0000313|EMBL:CAE49706.1};
GN OrderedLocusNames=DIP1182 {ECO:0000313|EMBL:CAE49706.1};
OS Corynebacterium diphtheriae (strain ATCC 700971 / NCTC 13129 / Biotype
OS gravis).
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales;
OC Corynebacteriaceae; Corynebacterium.
OX NCBI_TaxID=257309 {ECO:0000313|EMBL:CAE49706.1, ECO:0000313|Proteomes:UP000002198};
RN [1] {ECO:0000313|EMBL:CAE49706.1, ECO:0000313|Proteomes:UP000002198}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 700971 / NCTC 13129 / Biotype gravis
RC {ECO:0000313|Proteomes:UP000002198};
RX PubMed=14602910; DOI=10.1093/nar/gkg874;
RA Cerdeno-Tarraga A.M., Efstratiou A., Dover L.G., Holden M.T.G., Pallen M.,
RA Bentley S.D., Besra G.S., Churcher C., James K.D., De Zoysa A.,
RA Chillingworth T., Cronin A., Dowd L., Feltwell T., Hamlin N., Holroyd S.,
RA Jagels K., Moule S., Quail M.A., Rabbinowitsch E., Rutherford K.,
RA Thomson N.R., Unwin L., Whitehead S., Barrell B.G.Parkhill.J.;
RT "The complete genome sequence and analysis of Corynebacterium diphtheriae
RT NCTC13129.";
RL Nucleic Acids Res. 31:6516-6523(2003).
CC -!- FUNCTION: May be involved in recombinational repair of damaged DNA.
CC {ECO:0000256|ARBA:ARBA00003618, ECO:0000256|PIRNR:PIRNR003128}.
CC -!- SIMILARITY: Belongs to the RecN family. {ECO:0000256|ARBA:ARBA00009441,
CC ECO:0000256|PIRNR:PIRNR003128}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; BX248357; CAE49706.1; -; Genomic_DNA.
DR RefSeq; WP_010934868.1; NC_002935.2.
DR AlphaFoldDB; Q6NHF6; -.
DR STRING; 257309.DIP1182; -.
DR KEGG; cdi:DIP1182; -.
DR HOGENOM; CLU_018297_3_0_11; -.
DR Proteomes; UP000002198; Chromosome.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0006310; P:DNA recombination; IEA:InterPro.
DR GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
DR CDD; cd03241; ABC_RecN; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR004604; DNA_recomb/repair_RecN.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR003395; RecF/RecN/SMC_N.
DR NCBIfam; TIGR00634; recN; 1.
DR PANTHER; PTHR11059; DNA REPAIR PROTEIN RECN; 1.
DR PANTHER; PTHR11059:SF0; DNA REPAIR PROTEIN RECN; 1.
DR Pfam; PF02463; SMC_N; 1.
DR PIRSF; PIRSF003128; RecN; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW DNA damage {ECO:0000256|PIRNR:PIRNR003128};
KW DNA repair {ECO:0000256|PIRNR:PIRNR003128};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000002198}.
FT DOMAIN 4..523
FT /note="RecF/RecN/SMC N-terminal"
FT /evidence="ECO:0000259|Pfam:PF02463"
SQ SEQUENCE 579 AA; 62006 MW; D406491D4C87DCC5 CRC64;
MLSDITIHNL GVIPSASLEL SEGLTVLTGE TGAGKTMVVT GLRLLAGGRA EAQRVRSGSS
QAVVEGRFLL DSVAPESAEM ARAVVSAAGG ALDENGEVIV SRTVSAHGRS RAHLGGRSVP
AASLVEFSKE VLTIHGQNDQ LRLLNSDRQR DALDRFSQKI SALMTVYSEA YRAWKNLSKD
LQERQASKRE LAQEVDRLEF AIREISEVDP QPGEEADLLV QIARLQDVDD LRAQAVGALS
VIDGAAGVEG YATCDSSDAD AASDLIGQAL SSVRVSSDPT LQGVSQQLEA VTSILMEVSA
QLGGFLDELP ADPQMLDKLL QRQQALKQLT RKYASDIDGV IKWKLKAEQK LESIDVSPEA
LDQLKKETAL AERKMNDAGM ALRAARIEAA QELSNAVTKE LHGLAMPKAM FSVVVHPTEP
QPSGFDEVEF CLAPNNATDP RPLASSASGG ELSRVMLALE VILSAGQHGN TLVFDEVDAG
VGGRAAVEIG RRLARLAQNN QVIVVTHLPQ VAAYADTHLH VAKDVGESTV TSGVEKLSEQ
RRVEDLARML AGLEDTDTGR AHAKELFEKA QAENRAFRV
//
