ID Q6NI58_CORDI Unreviewed; 316 AA.
AC Q6NI58;
DT 05-JUL-2004, integrated into UniProtKB/TrEMBL.
DT 05-JUL-2004, sequence version 1.
DT 27-MAR-2024, entry version 82.
DE RecName: Full=exopolyphosphatase {ECO:0000256|ARBA:ARBA00012451};
DE EC=3.6.1.11 {ECO:0000256|ARBA:ARBA00012451};
GN OrderedLocusNames=DIP0920 {ECO:0000313|EMBL:CAE49436.1};
OS Corynebacterium diphtheriae (strain ATCC 700971 / NCTC 13129 / Biotype
OS gravis).
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales;
OC Corynebacteriaceae; Corynebacterium.
OX NCBI_TaxID=257309 {ECO:0000313|EMBL:CAE49436.1, ECO:0000313|Proteomes:UP000002198};
RN [1] {ECO:0000313|EMBL:CAE49436.1, ECO:0000313|Proteomes:UP000002198}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 700971 / NCTC 13129 / Biotype gravis
RC {ECO:0000313|Proteomes:UP000002198};
RX PubMed=14602910; DOI=10.1093/nar/gkg874;
RA Cerdeno-Tarraga A.M., Efstratiou A., Dover L.G., Holden M.T.G., Pallen M.,
RA Bentley S.D., Besra G.S., Churcher C., James K.D., De Zoysa A.,
RA Chillingworth T., Cronin A., Dowd L., Feltwell T., Hamlin N., Holroyd S.,
RA Jagels K., Moule S., Quail M.A., Rabbinowitsch E., Rutherford K.,
RA Thomson N.R., Unwin L., Whitehead S., Barrell B.G.Parkhill.J.;
RT "The complete genome sequence and analysis of Corynebacterium diphtheriae
RT NCTC13129.";
RL Nucleic Acids Res. 31:6516-6523(2003).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=[phosphate](n) + H2O = [phosphate](n-1) + H(+) + phosphate;
CC Xref=Rhea:RHEA:21528, Rhea:RHEA-COMP:9859, Rhea:RHEA-COMP:14279,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:16838,
CC ChEBI:CHEBI:43474; EC=3.6.1.11;
CC Evidence={ECO:0000256|ARBA:ARBA00000209};
CC -!- SIMILARITY: Belongs to the GppA/Ppx family.
CC {ECO:0000256|ARBA:ARBA00007125}.
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DR EMBL; BX248356; CAE49436.1; -; Genomic_DNA.
DR RefSeq; WP_010934670.1; NC_002935.2.
DR AlphaFoldDB; Q6NI58; -.
DR SMR; Q6NI58; -.
DR STRING; 257309.DIP0920; -.
DR KEGG; cdi:DIP0920; -.
DR PATRIC; fig|257309.4.peg.901; -.
DR HOGENOM; CLU_025908_1_2_11; -.
DR Proteomes; UP000002198; Chromosome.
DR Gene3D; 3.30.420.40; -; 1.
DR Gene3D; 3.30.420.150; Exopolyphosphatase. Domain 2; 1.
DR InterPro; IPR043129; ATPase_NBD.
DR InterPro; IPR003695; Ppx_GppA_N.
DR PANTHER; PTHR30005; EXOPOLYPHOSPHATASE; 1.
DR PANTHER; PTHR30005:SF0; RETROGRADE REGULATION PROTEIN 2; 1.
DR Pfam; PF02541; Ppx-GppA; 1.
DR SUPFAM; SSF53067; Actin-like ATPase domain; 2.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000002198}.
FT DOMAIN 18..310
FT /note="Ppx/GppA phosphatase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF02541"
SQ SEQUENCE 316 AA; 33415 MW; F4F64A30E62DDF16 CRC64;
MSVVAAVDCG TNSIRLLISE QTPTGLREIT RQMTIIRLGE GVDATGKIDP VAIERARVAL
SGYVDTMLAH KVTAVRMVAT SATRDASNKD DFFAMTADLL GAVVPGACAE VISGAEEAEL
SFIGAVADIP DTDRPVCVID LGGGSTEFVV GKKTGEILGA YSTQMGCVRL TERLMVSDPP
TAEEIAQARE YVDTQLTVAL DNVPIMQASM VVGCAGTFTT VAALALGLDS YDPQRIHGSV
HTADRLREET QRLIGETSQQ RAAHSVMHLG RADVIAGGSV VIEQILAMMQ RLGVSDSVTI
SEKDILDGIV ARLLEE
//
