ID   IAP1_OSHVF              Reviewed;         364 AA.
AC   Q6R7I2;
DT   22-SEP-2009, integrated into UniProtKB/Swiss-Prot.
DT   05-JUL-2004, sequence version 1.
DT   08-NOV-2023, entry version 71.
DE   RecName: Full=Putative apoptosis inhibitor ORF42;
GN   ORFNames=ORF42;
OS   Ostreid herpesvirus 1 (isolate France) (OsHV-1) (Pacific oyster
OS   herpesvirus).
OC   Viruses; Duplodnaviria; Heunggongvirae; Peploviricota; Herviviricetes;
OC   Herpesvirales; Malacoherpesviridae; Ostreavirus;
OC   Ostreavirus ostreidmalaco1; Ostreid herpesvirus 1.
OX   NCBI_TaxID=654903;
OH   NCBI_TaxID=29159; Crassostrea gigas (Pacific oyster) (Crassostrea angulata).
OH   NCBI_TaxID=6579; Pecten maximus (King scallop) (Pilgrim's clam).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=15604430; DOI=10.1099/vir.0.80382-0;
RA   Davison A.J., Trus B.L., Cheng N., Steven A.C., Watson M.S., Cunningham C.,
RA   Le Deuff R.M., Renault T.;
RT   "A novel class of herpesvirus with bivalve hosts.";
RL   J. Gen. Virol. 86:41-53(2005).
CC   -!- FUNCTION: May act as an apoptosis inhibitor.
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DR   EMBL; AY509253; AAS00933.1; -; Genomic_DNA.
DR   RefSeq; YP_024586.1; NC_005881.2.
DR   GeneID; 2948190; -.
DR   KEGG; vg:2948190; -.
DR   Proteomes; UP000007021; Segment.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   CDD; cd00022; BIR; 2.
DR   Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR   InterPro; IPR001370; BIR_rpt.
DR   InterPro; IPR001841; Znf_RING.
DR   InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR   PANTHER; PTHR10044:SF139; DEATH-ASSOCIATED INHIBITOR OF APOPTOSIS 2; 1.
DR   PANTHER; PTHR10044; INHIBITOR OF APOPTOSIS; 1.
DR   Pfam; PF00653; BIR; 2.
DR   Pfam; PF13920; zf-C3HC4_3; 1.
DR   SMART; SM00238; BIR; 2.
DR   SMART; SM00184; RING; 1.
DR   SUPFAM; SSF57924; Inhibitor of apoptosis (IAP) repeat; 3.
DR   PROSITE; PS01282; BIR_REPEAT_1; 1.
DR   PROSITE; PS50143; BIR_REPEAT_2; 2.
DR   PROSITE; PS50089; ZF_RING_2; 1.
PE   4: Predicted;
KW   Metal-binding; Reference proteome; Repeat; Zinc; Zinc-finger.
FT   CHAIN           1..364
FT                   /note="Putative apoptosis inhibitor ORF42"
FT                   /id="PRO_0000385025"
FT   REPEAT          24..89
FT                   /note="BIR 1"
FT   REPEAT          127..193
FT                   /note="BIR 2"
FT   REPEAT          236..300
FT                   /note="BIR 3"
FT   ZN_FING         315..350
FT                   /note="RING-type"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00175"
FT   REGION          83..126
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   364 AA;  42037 MW;  5510BF38D37B1DE9 CRC64;
     MGISELEYLP QTTVNALLQY DNVRLATFRG YEYATDQWKK YLSDTKFFKV GEVDQIQCVF
     CRMKTSIRNE ERIKKHVADC REGVVSAPQQ QPPPPPSTSI GAVGGDPRPE DMNVPERGWD
     PPMSKDPKST FLGKWPHSEY ISIDSMVAEG FEFIGPGDRV QCRHCKVILR NWETTDIPSS
     EHERNAPRCP LVVQRYLTRM REDDERRDRE LKEVQQRRKM DMNKAFSQDM SKLENRIASL
     KFWPGPIRDI EKVARTGFFY TGEKDMLTCY ACACKLINWE KNDDPIKEHK INFPHCANMA
     DVKWSDVGFS NDEECVICLG AKADTILKPC LHYSLCYGCS TQVQKCPLCR KKIEKRVQTT
     NVLQ
//