ID Q6T3W4_PLABE Unreviewed; 220 AA.
AC Q6T3W4;
DT 05-JUL-2004, integrated into UniProtKB/TrEMBL.
DT 05-JUL-2004, sequence version 1.
DT 24-JAN-2024, entry version 58.
DE SubName: Full=UIS4 {ECO:0000313|EMBL:AAR08138.1};
DE SubName: Full=Up-regulated in infective sporozoites {ECO:0000313|EMBL:CXI06603.1};
GN Name=UIS4 {ECO:0000313|EMBL:CXI06603.1};
GN ORFNames=PBK173_000070700 {ECO:0000313|EMBL:CXI06603.1},
GN PBNK65E_000066900 {ECO:0000313|EMBL:SCN22780.1}, PBNK65NY_000066400
GN {ECO:0000313|EMBL:SCL92487.1}, PBSP11A_000066600
GN {ECO:0000313|EMBL:SCM15647.1}, PBSP11RLL_000066700
GN {ECO:0000313|EMBL:SCM17441.1};
OS Plasmodium berghei.
OC Eukaryota; Sar; Alveolata; Apicomplexa; Aconoidasida; Haemosporida;
OC Plasmodiidae; Plasmodium; Plasmodium (Vinckeia).
OX NCBI_TaxID=5821 {ECO:0000313|EMBL:AAR08138.1};
RN [1] {ECO:0000313|EMBL:AAR08138.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=NK65 {ECO:0000313|EMBL:AAR08138.1};
RX PubMed=12177071; DOI=10.1074/jbc.M207315200;
RA Matuschewski K., Ross J., Brown S.M., Kaiser K., Nussenzweig V.,
RA Kappe S.H.;
RT "Infectivity-associated changes in the transcriptional repertoire of the
RT malaria parasite sporozoite stage.";
RL J. Biol. Chem. 277:41948-41953(2002).
RN [2] {ECO:0000313|EMBL:AAR08138.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=NK65 {ECO:0000313|EMBL:AAR08138.1};
RX PubMed=14982620; DOI=10.1046/j.1365-2958.2003.03909.x;
RA Kaiser K., Matuschewski K., Camargo N., Ross J., Kappe S.H.;
RT "Differential transcriptome profiling identifies Plasmodium genes encoding
RT pre-erythrocytic stage-specific proteins.";
RL Mol. Microbiol. 51:1221-1232(2004).
RN [3] {ECO:0000313|EMBL:AAR08138.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=NK65 {ECO:0000313|EMBL:AAR08138.1};
RX PubMed=15699336; DOI=10.1073/pnas.0408442102;
RA Mueller A.K., Camargo N., Kaiser K., Andorfer C., Frevert U.,
RA Matuschewski K., Kappe S.H.;
RT "Plasmodium liver stage developmental arrest by depletion of a protein at
RT the parasite-host interface.";
RL Proc. Natl. Acad. Sci. U.S.A. 102:3022-3027(2005).
RN [4] {ECO:0000313|EMBL:SCN22780.1, ECO:0000313|Proteomes:UP000220214}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K173 {ECO:0000313|EMBL:CXI06603.1,
RC ECO:0000313|Proteomes:UP000069549}, NK65 ny
RC {ECO:0000313|EMBL:SCL92487.1, ECO:0000313|Proteomes:UP000516480},
RC NK65e {ECO:0000313|EMBL:SCN22780.1,
RC ECO:0000313|Proteomes:UP000220214}, SP11 Antwerpcl1
RC {ECO:0000313|EMBL:SCM15647.1, ECO:0000313|Proteomes:UP000219860}, and
RC SP11 RLL {ECO:0000313|EMBL:SCM17441.1,
RC ECO:0000313|Proteomes:UP000219974};
RG Pathogen Informatics;
RL Submitted (MAY-2016) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; AY437807; AAR08138.1; -; Genomic_DNA.
DR EMBL; LT160025; CXI06603.1; -; Genomic_DNA.
DR EMBL; LT608141; SCL92487.1; -; Genomic_DNA.
DR EMBL; LT608253; SCM15647.1; -; Genomic_DNA.
DR EMBL; LT608269; SCM17441.1; -; Genomic_DNA.
DR EMBL; LT614631; SCN22780.1; -; Genomic_DNA.
DR AlphaFoldDB; Q6T3W4; -.
DR VEuPathDB; PlasmoDB:PBANKA_0501200; -.
DR OMA; DNIVYHD; -.
DR Proteomes; UP000069549; Chromosome 5.
DR Proteomes; UP000219860; Chromosome 5.
DR Proteomes; UP000219974; Chromosome 5.
DR Proteomes; UP000220214; Chromosome 5.
DR Proteomes; UP000516480; Chromosome 5.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR Pfam; PF09716; ETRAMP; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius}; Signal {ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..25
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 26..220
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5014310664"
FT TRANSMEM 55..76
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REGION 101..127
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 101..123
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 220 AA; 25233 MW; 21A0A8E338243816 CRC64;
MKTTYVSLFF IILLIFGGFE YKASPIDETN DSKPNKVKLI EKINSLFKNK RNTKIAAIAA
SIAGSAIALA LTLACMNPEV REKFRIGKRI KEFDDVNTPQ DISLINPVEN PYPENSPENS
PENSPEKYIE ESHKHYTKRF LEQYTEPKPS DHTYSYSPTE EAYNTHYMAS DTHEDYGKLF
TDEHKDEIND NIVYHDELSD LVGEGNNVYN MENKSFGPYI
//
