ID Q6VUQ5_SOLLC Unreviewed; 306 AA.
AC Q6VUQ5;
DT 05-JUL-2004, integrated into UniProtKB/TrEMBL.
DT 05-JUL-2004, sequence version 1.
DT 27-MAR-2024, entry version 112.
DE RecName: Full=Serine/threonine-protein phosphatase {ECO:0000256|RuleBase:RU004273};
DE EC=3.1.3.16 {ECO:0000256|RuleBase:RU004273};
GN Name=PP2Ac2 {ECO:0000313|EMBL:AAQ67226.1};
GN Synonyms=544262 {ECO:0000313|EnsemblPlants:Solyc01g011340.3.1};
OS Solanum lycopersicum (Tomato) (Lycopersicon esculentum).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC asterids; lamiids; Solanales; Solanaceae; Solanoideae; Solaneae; Solanum;
OC Solanum subgen. Lycopersicon.
OX NCBI_TaxID=4081 {ECO:0000313|EMBL:AAQ67226.1};
RN [1] {ECO:0000313|EMBL:AAQ67226.1}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=15125764; DOI=10.1111/j.1365-313X.2004.02073.x;
RA He X., Anderson J.C., del Pozo O., Gu Y.Q., Tang X., Martin G.B.;
RT "Silencing of subfamily I of protein phosphatase 2A catalytic subunits
RT results in activation of plant defense responses and localized cell
RT death.";
RL Plant J. 38:563-577(2004).
RN [2] {ECO:0000313|EnsemblPlants:Solyc01g011340.3.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Heinz 1706 {ECO:0000313|EnsemblPlants:Solyc01g011340.3.1};
RX PubMed=22660326; DOI=10.1038/nature11119;
RG Tomato Genome Consortium;
RT "The tomato genome sequence provides insights into fleshy fruit
RT evolution.";
RL Nature 485:635-641(2012).
RN [3] {ECO:0000313|EnsemblPlants:Solyc01g011340.3.1}
RP IDENTIFICATION.
RC STRAIN=cv. Heinz 1706 {ECO:0000313|EnsemblPlants:Solyc01g011340.3.1};
RG EnsemblPlants;
RL Submitted (JAN-2019) to UniProtKB.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] +
CC phosphate; Xref=Rhea:RHEA:47004, Rhea:RHEA-COMP:11060, Rhea:RHEA-
CC COMP:11605, ChEBI:CHEBI:15377, ChEBI:CHEBI:30013, ChEBI:CHEBI:43474,
CC ChEBI:CHEBI:61977; EC=3.1.3.16;
CC Evidence={ECO:0000256|RuleBase:RU004273};
CC -!- SIMILARITY: Belongs to the PPP phosphatase family.
CC {ECO:0000256|RuleBase:RU004273}.
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DR EMBL; AY325818; AAQ67226.1; -; mRNA.
DR RefSeq; NP_001233804.1; NM_001246875.2.
DR AlphaFoldDB; Q6VUQ5; -.
DR SMR; Q6VUQ5; -.
DR STRING; 4081.Q6VUQ5; -.
DR PaxDb; 4081-Solyc01g011340-2-1; -.
DR EnsemblPlants; Solyc01g011340.3.1; Solyc01g011340.3.1; Solyc01g011340.3.
DR GeneID; 544262; -.
DR Gramene; Solyc01g011340.3.1; Solyc01g011340.3.1; Solyc01g011340.3.
DR KEGG; sly:544262; -.
DR eggNOG; KOG0371; Eukaryota.
DR HOGENOM; CLU_004962_8_1_1; -.
DR InParanoid; Q6VUQ5; -.
DR OMA; MDDKTFT; -.
DR OrthoDB; 19833at2759; -.
DR Proteomes; UP000004994; Chromosome 1.
DR GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR GO; GO:0017018; F:myosin phosphatase activity; IEA:UniProtKB-EC.
DR GO; GO:0004722; F:protein serine/threonine phosphatase activity; IBA:GO_Central.
DR GO; GO:0000278; P:mitotic cell cycle; IBA:GO_Central.
DR CDD; cd07415; MPP_PP2A_PP4_PP6; 1.
DR Gene3D; 3.60.21.10; -; 1.
DR InterPro; IPR004843; Calcineurin-like_PHP_ApaH.
DR InterPro; IPR029052; Metallo-depent_PP-like.
DR InterPro; IPR047129; PPA2-like.
DR InterPro; IPR006186; Ser/Thr-sp_prot-phosphatase.
DR PANTHER; PTHR45619; SERINE/THREONINE-PROTEIN PHOSPHATASE PP2A-RELATED; 1.
DR PANTHER; PTHR45619:SF62; SERINE_THREONINE-PROTEIN PHOSPHATASE PP2A-2 CATALYTIC SUBUNIT; 1.
DR Pfam; PF00149; Metallophos; 1.
DR PRINTS; PR00114; STPHPHTASE.
DR SMART; SM00156; PP2Ac; 1.
DR SUPFAM; SSF56300; Metallo-dependent phosphatases; 1.
DR PROSITE; PS00125; SER_THR_PHOSPHATASE; 1.
PE 2: Evidence at transcript level;
KW Hydrolase {ECO:0000256|RuleBase:RU004273};
KW Manganese {ECO:0000256|ARBA:ARBA00023211};
KW Reference proteome {ECO:0000313|Proteomes:UP000004994}.
FT DOMAIN 111..116
FT /note="Serine/threonine specific protein phosphatases"
FT /evidence="ECO:0000259|PROSITE:PS00125"
SQ SEQUENCE 306 AA; 35010 MW; C0719F26F8FCA0E5 CRC64;
MPSHADLDRQ IEQLMECKPL SEADVKTLCD QARAILVEEW NVQPVKCPVT VCGDIHGQFY
DLIELFRIGG NAPDTNYLFM GDYVDRGYYS VETVTLLVAL KVRYRDRITI LRGNHESRQI
TQVYGFYDEC LRKYGNANVW KYFTDLFDYL PLTALIESQI FCLHGGLSPS LDTLDNIRAL
DRIQEVPHEG PMCDLLWSDP DDRCGWGISP RGAGYTFGQD IASQFNHTNG LTLISRAHQL
VMEGFNWCQD KNVVTVFSAP NYCYRCGNMA AILEIGENME QNFLQFDPAP RQIEPDTTRK
TPDYFL
//
