ID   Q6YPX4_ONYPE            Unreviewed;       324 AA.
AC   Q6YPX4;
DT   05-JUL-2004, integrated into UniProtKB/TrEMBL.
DT   05-JUL-2004, sequence version 1.
DT   27-MAR-2024, entry version 95.
DE   SubName: Full=Thiamine pyrophosphate-dependent dehydrogenase, E1 component beta subunit {ECO:0000313|EMBL:BAD04686.1};
GN   Name=acoB {ECO:0000313|EMBL:BAD04686.1};
GN   OrderedLocusNames=PAM_601 {ECO:0000313|EMBL:BAD04686.1};
OS   Onion yellows phytoplasma (strain OY-M).
OC   Bacteria; Mycoplasmatota; Mollicutes; Acholeplasmatales;
OC   Acholeplasmataceae; Phytoplasma; 16SrI (Aster yellows group).
OX   NCBI_TaxID=262768 {ECO:0000313|EMBL:BAD04686.1, ECO:0000313|Proteomes:UP000002523};
RN   [1] {ECO:0000313|EMBL:BAD04686.1, ECO:0000313|Proteomes:UP000002523}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=OY-M {ECO:0000313|Proteomes:UP000002523};
RX   PubMed=14661021; DOI=10.1038/ng1277;
RA   Oshima K., Kakizawa S., Nishigawa H., Jung H.-Y., Wei W., Suzuki S.,
RA   Arashida R., Nakata D., Miyata S., Ugaki M., Namba S.;
RT   "Reductive evolution suggested from the complete genome sequence of a
RT   plant-pathogenic phytoplasma.";
RL   Nat. Genet. 36:27-29(2004).
CC   -!- COFACTOR:
CC       Name=thiamine diphosphate; Xref=ChEBI:CHEBI:58937;
CC         Evidence={ECO:0000256|ARBA:ARBA00001964};
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DR   EMBL; AP006628; BAD04686.1; -; Genomic_DNA.
DR   AlphaFoldDB; Q6YPX4; -.
DR   STRING; 262768.PAM_601; -.
DR   KEGG; poy:PAM_601; -.
DR   eggNOG; COG0022; Bacteria.
DR   HOGENOM; CLU_012907_1_0_14; -.
DR   BioCyc; OYEL262768:G1G26-725-MONOMER; -.
DR   Proteomes; UP000002523; Chromosome.
DR   GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR   CDD; cd07036; TPP_PYR_E1-PDHc-beta_like; 1.
DR   Gene3D; 3.40.50.920; -; 1.
DR   Gene3D; 3.40.50.970; -; 1.
DR   InterPro; IPR029061; THDP-binding.
DR   InterPro; IPR009014; Transketo_C/PFOR_II.
DR   InterPro; IPR005475; Transketolase-like_Pyr-bd.
DR   InterPro; IPR033248; Transketolase_C.
DR   PANTHER; PTHR42980:SF1; 2-OXOISOVALERATE DEHYDROGENASE SUBUNIT BETA, MITOCHONDRIAL; 1.
DR   PANTHER; PTHR42980; 2-OXOISOVALERATE DEHYDROGENASE SUBUNIT BETA-RELATED; 1.
DR   Pfam; PF02779; Transket_pyr; 1.
DR   Pfam; PF02780; Transketolase_C; 1.
DR   SMART; SM00861; Transket_pyr; 1.
DR   SUPFAM; SSF52518; Thiamin diphosphate-binding fold (THDP-binding); 1.
DR   SUPFAM; SSF52922; TK C-terminal domain-like; 1.
PE   4: Predicted;
FT   DOMAIN          4..179
FT                   /note="Transketolase-like pyrimidine-binding"
FT                   /evidence="ECO:0000259|SMART:SM00861"
SQ   SEQUENCE   324 AA;  35258 MW;  02F10AE2EB31416D CRC64;
     MASMTLLDAI NQTLDSKLAK DPRVVLFGQD VGKLGGVFRV TKGLQDKHGE TRVFNAPIAE
     SSIIGSAIGL AINGMRPVAE IQFDGFIFVG LEDLFAHAAR LRNRSRGNYT VPMVVRVPVG
     GGVKSLEHHS ESLEVILGSV PGLKVVIPSN PYDAKGLLMA AINDPDPVVY MEPKRIYRGF
     RQEVPETDYE VQIGKAKVVQ EGTDITVVAW GAMVPETLLA LKQLDPNVSV ELIDLRTINP
     IDRETVITSV KKTGRFLVVH EACKTYGPAG ELMALVNEQA FLYLDAAPAR VTGNDITMPL
     AKAEHYQFLS PEKIADAIKK VVCE
//