ID ORR33_ORYSJ Reviewed; 614 AA.
AC Q6ZC03; A0A0P0XGS7;
DT 16-SEP-2015, integrated into UniProtKB/Swiss-Prot.
DT 05-JUL-2004, sequence version 1.
DT 24-JAN-2024, entry version 131.
DE RecName: Full=Two-component response regulator ORR33 {ECO:0000305};
DE AltName: Full=OsRRA19 {ECO:0000303|PubMed:16891544};
GN Name=RR33 {ECO:0000303|PubMed:17284581};
GN OrderedLocusNames=Os08g0458600 {ECO:0000312|EMBL:BAF23885.1},
GN LOC_Os08g35670 {ECO:0000305};
GN ORFNames=P0493A04.24 {ECO:0000312|EMBL:BAD09592.1};
OS Oryza sativa subsp. japonica (Rice).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX NCBI_TaxID=39947;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=16100779; DOI=10.1038/nature03895;
RG International rice genome sequencing project (IRGSP);
RT "The map-based sequence of the rice genome.";
RL Nature 436:793-800(2005).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=18089549; DOI=10.1093/nar/gkm978;
RG The rice annotation project (RAP);
RT "The rice annotation project database (RAP-DB): 2008 update.";
RL Nucleic Acids Res. 36:D1028-D1033(2008).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=24280374; DOI=10.1186/1939-8433-6-4;
RA Kawahara Y., de la Bastide M., Hamilton J.P., Kanamori H., McCombie W.R.,
RA Ouyang S., Schwartz D.C., Tanaka T., Wu J., Zhou S., Childs K.L.,
RA Davidson R.M., Lin H., Quesada-Ocampo L., Vaillancourt B., Sakai H.,
RA Lee S.S., Kim J., Numa H., Itoh T., Buell C.R., Matsumoto T.;
RT "Improvement of the Oryza sativa Nipponbare reference genome using next
RT generation sequence and optical map data.";
RL Rice 6:4-4(2013).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=12869764; DOI=10.1126/science.1081288;
RG The rice full-length cDNA consortium;
RT "Collection, mapping, and annotation of over 28,000 cDNA clones from
RT japonica rice.";
RL Science 301:376-379(2003).
RN [5]
RP DISRUPTION PHENOTYPE.
RX PubMed=16891544; DOI=10.1104/pp.106.086371;
RA Pareek A., Singh A., Kumar M., Kushwaha H.R., Lynn A.M.,
RA Singla-Pareek S.L.;
RT "Whole-genome analysis of Oryza sativa reveals similar architecture of two-
RT component signaling machinery with Arabidopsis.";
RL Plant Physiol. 142:380-397(2006).
RN [6]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=17284581; DOI=10.1104/pp.106.093666;
RA Schaller G.E., Doi K., Hwang I., Kieber J.J., Khurana J.P., Kurata N.,
RA Mizuno T., Pareek A., Shiu S.H., Wu P., Yip W.K.;
RT "Nomenclature for two-component signaling elements of rice.";
RL Plant Physiol. 143:555-557(2007).
RN [7]
RP SUBCELLULAR LOCATION.
RX PubMed=22383541; DOI=10.1104/pp.111.192765;
RA Tsai Y.C., Weir N.R., Hill K., Zhang W., Kim H.J., Shiu S.H.,
RA Schaller G.E., Kieber J.J.;
RT "Characterization of genes involved in cytokinin signaling and metabolism
RT from rice.";
RL Plant Physiol. 158:1666-1684(2012).
CC -!- FUNCTION: Functions as a response regulator involved in His-to-Asp
CC phosphorelay signal transduction system. Phosphorylation of the Asp
CC residue in the receiver domain activates the ability of the protein to
CC promote the transcription of target genes. May directly activate some
CC type-A response regulators in response to cytokinins.
CC {ECO:0000250|UniProtKB:Q940D0}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000269|PubMed:22383541}.
CC -!- PTM: Two-component system major event consists of a His-to-Asp
CC phosphorelay between a sensor histidine kinase (HK) and a response
CC regulator (RR). In plants, the His-to-Asp phosphorelay involves an
CC additional intermediate named Histidine-containing phosphotransfer
CC protein (HPt). This multistep phosphorelay consists of a His-Asp-His-
CC Asp sequential transfer of a phosphate group between first an His and
CC an Asp of the HK protein, followed by the transfer to a conserved His
CC of the HPt protein and finally the transfer to an Asp in the receiver
CC domain of the RR protein. {ECO:0000305}.
CC -!- DISRUPTION PHENOTYPE: Low fertility. {ECO:0000269|PubMed:16891544}.
CC -!- SIMILARITY: Belongs to the ARR family. Type-B subfamily. {ECO:0000305}.
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DR EMBL; AP004586; BAD09592.1; -; Genomic_DNA.
DR EMBL; AP008214; BAF23885.1; -; Genomic_DNA.
DR EMBL; AP014964; BAT05748.1; -; Genomic_DNA.
DR EMBL; AK107384; BAG98039.1; -; mRNA.
DR RefSeq; XP_015649581.1; XM_015794095.1.
DR AlphaFoldDB; Q6ZC03; -.
DR SMR; Q6ZC03; -.
DR STRING; 39947.Q6ZC03; -.
DR PaxDb; 39947-Q6ZC03; -.
DR EnsemblPlants; Os08t0458600-01; Os08t0458600-01; Os08g0458600.
DR GeneID; 4345758; -.
DR Gramene; Os08t0458600-01; Os08t0458600-01; Os08g0458600.
DR KEGG; osa:4345758; -.
DR eggNOG; ENOG502RRR6; Eukaryota.
DR HOGENOM; CLU_027175_0_0_1; -.
DR InParanoid; Q6ZC03; -.
DR OMA; VMARLWR; -.
DR OrthoDB; 359108at2759; -.
DR Proteomes; UP000000763; Chromosome 8.
DR Proteomes; UP000059680; Chromosome 8.
DR Genevisible; Q6ZC03; OS.
DR GO; GO:0005829; C:cytosol; IBA:GO_Central.
DR GO; GO:0005634; C:nucleus; IDA:UniProtKB.
DR GO; GO:0032993; C:protein-DNA complex; IBA:GO_Central.
DR GO; GO:0000156; F:phosphorelay response regulator activity; IBA:GO_Central.
DR GO; GO:0000976; F:transcription cis-regulatory region binding; IBA:GO_Central.
DR GO; GO:0009736; P:cytokinin-activated signaling pathway; IEA:UniProtKB-KW.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IBA:GO_Central.
DR Gene3D; 3.40.50.2300; -; 1.
DR InterPro; IPR011006; CheY-like_superfamily.
DR InterPro; IPR001789; Sig_transdc_resp-reg_receiver.
DR SUPFAM; SSF52172; CheY-like; 1.
DR PROSITE; PS50110; RESPONSE_REGULATORY; 1.
PE 2: Evidence at transcript level;
KW Activator; Cytokinin signaling pathway; Nucleus; Phosphoprotein;
KW Reference proteome; Two-component regulatory system.
FT CHAIN 1..614
FT /note="Two-component response regulator ORR33"
FT /id="PRO_0000433857"
FT DOMAIN 14..139
FT /note="Response regulatory"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00169"
FT REGION 200..220
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT MOD_RES 67
FT /note="4-aspartylphosphate"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00169"
SQ SEQUENCE 614 AA; 64789 MW; 463624B140A291C2 CRC64;
MDQARISFFP DGLRVMIIDD DAKAVRRATA TLSQLQYAVV ATHSTASAGL RALSGDNVVE
IQAILCDVHK VVSSGFDFRR VVESELRIPV IYLLSKMEEE DMVAGEDAEF LNHLLLTATY
IVRKPLNPTV MARLWRVVAW RMYCLEERIQ ANVAANAGAG GEDDDDDDDV VIVEEPQVHF
KVVRRTSGGS RKRQLTINVV DDGNRGSGSG GGGGGGADAN PTRILQHITS NLQEFRTKHQ
KKDMAIERPL ISSDSMFLKA ILPTLKISPC NPLTLTGGIG SSSVAAEAFA GGSSSAAPLQ
IPVFQQQSTG NGNTVISFSN NASPMAMRAP TDNTMISFNN VSAAPVANAV ISFSNISRSA
AMQAPAARGQ HLSGDVQQLD FPQQKLYFGP FSYQGPPPPS MHNHINLLPP TSSPVTCSMD
KGKVPIIELP YGMPVDDFLV SQTTYGGAGP SIGATDAAAA AYPYTDAPSN NVATGCLMVP
PMGPAFSITE PTVVAQGEGT GTGVDAGTSE KNAIVEAPNN PAPLMVLDQV AADAAMDVQE
DIMFSLESLL GPDYDLLPME DVSAPDTAAA GDAAGGSLDG EEGGMDIGWD LDLDDILVEN
VNDFAFLDNL AGSE
//
