ID FAS2_ORYSJ Reviewed; 505 AA.
AC Q6ZD63; A0A0N7KP55;
DT 31-OCT-2012, integrated into UniProtKB/Swiss-Prot.
DT 05-JUL-2004, sequence version 1.
DT 24-JAN-2024, entry version 130.
DE RecName: Full=Chromatin assembly factor 1 subunit FAS2 homolog;
DE Short=CAF-1 subunit FAS2 homolog;
DE AltName: Full=CAF-1 p60 homolog;
DE AltName: Full=Protein FASCIATA 2 homolog;
GN Name=FAS2; OrderedLocusNames=Os08g0108200, LOC_Os08g01680;
GN ORFNames=OsJ_25768, P0450B04.31;
OS Oryza sativa subsp. japonica (Rice).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX NCBI_TaxID=39947;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=16100779; DOI=10.1038/nature03895;
RG International rice genome sequencing project (IRGSP);
RT "The map-based sequence of the rice genome.";
RL Nature 436:793-800(2005).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=18089549; DOI=10.1093/nar/gkm978;
RG The rice annotation project (RAP);
RT "The rice annotation project database (RAP-DB): 2008 update.";
RL Nucleic Acids Res. 36:D1028-D1033(2008).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=24280374; DOI=10.1186/1939-8433-6-4;
RA Kawahara Y., de la Bastide M., Hamilton J.P., Kanamori H., McCombie W.R.,
RA Ouyang S., Schwartz D.C., Tanaka T., Wu J., Zhou S., Childs K.L.,
RA Davidson R.M., Lin H., Quesada-Ocampo L., Vaillancourt B., Sakai H.,
RA Lee S.S., Kim J., Numa H., Itoh T., Buell C.R., Matsumoto T.;
RT "Improvement of the Oryza sativa Nipponbare reference genome using next
RT generation sequence and optical map data.";
RL Rice 6:4-4(2013).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=15685292; DOI=10.1371/journal.pbio.0030038;
RA Yu J., Wang J., Lin W., Li S., Li H., Zhou J., Ni P., Dong W., Hu S.,
RA Zeng C., Zhang J., Zhang Y., Li R., Xu Z., Li S., Li X., Zheng H., Cong L.,
RA Lin L., Yin J., Geng J., Li G., Shi J., Liu J., Lv H., Li J., Wang J.,
RA Deng Y., Ran L., Shi X., Wang X., Wu Q., Li C., Ren X., Wang J., Wang X.,
RA Li D., Liu D., Zhang X., Ji Z., Zhao W., Sun Y., Zhang Z., Bao J., Han Y.,
RA Dong L., Ji J., Chen P., Wu S., Liu J., Xiao Y., Bu D., Tan J., Yang L.,
RA Ye C., Zhang J., Xu J., Zhou Y., Yu Y., Zhang B., Zhuang S., Wei H.,
RA Liu B., Lei M., Yu H., Li Y., Xu H., Wei S., He X., Fang L., Zhang Z.,
RA Zhang Y., Huang X., Su Z., Tong W., Li J., Tong Z., Li S., Ye J., Wang L.,
RA Fang L., Lei T., Chen C.-S., Chen H.-C., Xu Z., Li H., Huang H., Zhang F.,
RA Xu H., Li N., Zhao C., Li S., Dong L., Huang Y., Li L., Xi Y., Qi Q.,
RA Li W., Zhang B., Hu W., Zhang Y., Tian X., Jiao Y., Liang X., Jin J.,
RA Gao L., Zheng W., Hao B., Liu S.-M., Wang W., Yuan L., Cao M.,
RA McDermott J., Samudrala R., Wang J., Wong G.K.-S., Yang H.;
RT "The genomes of Oryza sativa: a history of duplications.";
RL PLoS Biol. 3:266-281(2005).
RN [5]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=12869764; DOI=10.1126/science.1081288;
RG The rice full-length cDNA consortium;
RT "Collection, mapping, and annotation of over 28,000 cDNA clones from
RT japonica rice.";
RL Science 301:376-379(2003).
CC -!- FUNCTION: Component of the chromatin assembly factor complex (CAF-1)
CC involved in chromatin assembly following DNA replication and DNA
CC repair. Required for several aspects of development, including apical
CC meristem maintenance by regulating the durations of the S- and G2-
CC phases of the cell cycle through its chromatin assembly activity (By
CC similarity). {ECO:0000250}.
CC -!- SUBUNIT: Component of the chromatin assembly factor 1 (CAF-1) complex,
CC composed of FSM (FAS1), FAS2 and MSI1. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the WD repeat HIR1 family. {ECO:0000305}.
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DR EMBL; AP004462; BAD09397.1; -; Genomic_DNA.
DR EMBL; AP008214; BAF22718.1; -; Genomic_DNA.
DR EMBL; AP014964; BAT03474.1; -; Genomic_DNA.
DR EMBL; CM000145; EAZ41259.1; -; Genomic_DNA.
DR EMBL; AK121823; -; NOT_ANNOTATED_CDS; mRNA.
DR RefSeq; XP_015648431.1; XM_015792945.1.
DR AlphaFoldDB; Q6ZD63; -.
DR SMR; Q6ZD63; -.
DR STRING; 39947.Q6ZD63; -.
DR PaxDb; 39947-Q6ZD63; -.
DR EnsemblPlants; Os08t0108200-01; Os08t0108200-01; Os08g0108200.
DR GeneID; 4344464; -.
DR Gramene; Os08t0108200-01; Os08t0108200-01; Os08g0108200.
DR KEGG; osa:4344464; -.
DR eggNOG; KOG1009; Eukaryota.
DR HOGENOM; CLU_010127_4_0_1; -.
DR InParanoid; Q6ZD63; -.
DR OMA; QIYWHES; -.
DR OrthoDB; 5478541at2759; -.
DR Proteomes; UP000000763; Chromosome 8.
DR Proteomes; UP000007752; Chromosome 8.
DR Proteomes; UP000059680; Chromosome 8.
DR Genevisible; Q6ZD63; OS.
DR GO; GO:0033186; C:CAF-1 complex; IBA:GO_Central.
DR GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR GO; GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.
DR GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
DR GO; GO:0006335; P:DNA replication-dependent chromatin assembly; IEA:InterPro.
DR GO; GO:0006334; P:nucleosome assembly; IBA:GO_Central.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 2.
DR InterPro; IPR001632; Gprotein_B.
DR InterPro; IPR045145; PTHR15271.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR InterPro; IPR001680; WD40_rpt.
DR PANTHER; PTHR15271; CHROMATIN ASSEMBLY FACTOR 1 SUBUNIT B; 1.
DR PANTHER; PTHR15271:SF4; CHROMATIN ASSEMBLY FACTOR 1 SUBUNIT B; 1.
DR Pfam; PF00400; WD40; 5.
DR PRINTS; PR00319; GPROTEINB.
DR SMART; SM00320; WD40; 5.
DR SUPFAM; SSF50978; WD40 repeat-like; 1.
DR PROSITE; PS00678; WD_REPEATS_1; 1.
DR PROSITE; PS50082; WD_REPEATS_2; 4.
DR PROSITE; PS50294; WD_REPEATS_REGION; 1.
PE 2: Evidence at transcript level;
KW Chromatin regulator; DNA damage; DNA recombination; DNA repair; Nucleus;
KW Reference proteome; Repeat; Transcription; Transcription regulation;
KW WD repeat.
FT CHAIN 1..505
FT /note="Chromatin assembly factor 1 subunit FAS2 homolog"
FT /id="PRO_0000420142"
FT REPEAT 11..50
FT /note="WD 1"
FT REPEAT 62..101
FT /note="WD 2"
FT REPEAT 110..149
FT /note="WD 3"
FT REPEAT 152..191
FT /note="WD 4"
FT REPEAT 223..268
FT /note="WD 5"
FT REPEAT 278..333
FT /note="WD 6"
FT REPEAT 337..378
FT /note="WD 7"
FT REGION 479..505
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 479..498
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT CONFLICT 68
FT /note="N -> D (in Ref. 5; AK121823)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 505 AA; 55320 MW; C369FAE2586553AC CRC64;
MRGGTVQINW HEQQPVLTLD FHPVSRRLAT GGSDHDIKIW VIASDDSDKK LPTATYHSSL
SSHSSAVNVL RFSPSGENLA SGADGGGIII WKLHSTDDGE AWKVQKTLLF HHKDVLDLQW
SQDGAFLVSA SVDNSCIVWD AIKGSVQQKL EGHLHYVQGV AWDPLGQYIA SLSSDRTCRI
YANKPQGKSK NTDRMNFVCQ HTLVKAEHQN HDESKPPVRA HLFHDETLPS FFRRLAWSPD
GSFLVLPAGL CKYSSEVINT AYVMSRRDLS RPAIQLPGAS KAIVAVRFCP VLFKLRGSQS
DCFFKLPYRV IFAVATLNSL YVYDTESVAP ILIHAGLHYA AITDIAWSSD AKYLAVSSRD
CFCTIIEFEN EELGLPYNLS GTKELDEGNT NCENMKPLKV DSMEIDAGSS KAKIKASSAA
VEVTPSPPVL AQNNILMTKD VAEGNATSEN DRPSAVDNME VDVGENKAKM EVTPVAVQVT
APPVSTKNSA SSKPTKKRIT PIAIN
//
